High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

• Autor(a) principal: Barbosa,Diego de Lacerda
• Data de Publicação: 2017
• Outros Autores: Hochhegger,Bruno, Souza Jr.,Arthur Soares, Zanetti,Gláucia, Escuissato,Dante Luiz, Meirelles,Gustavo de Souza Portes, Funari,Marcelo Buarque de Gusmão, Marchiori,Edson
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Radiologia Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000300148
• topic: Hantavirus; Computed tomography; Lung infections

Abstract Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema.