Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography

Detalhes bibliográficos
Autor(a) principal: Monjardim,Rodrigo da Fonseca
Data de Publicação: 2013
Outros Autores: Costa,Danilo Manuel Cerqueira, Romano,Ricardo Francisco Tavares, Salvadori,Priscila Silveira, Santos,Jaime de Vargas Conde dos, Atzingen,Augusto Castelli Von, Shigueoka,David Carlos, D'Ippolito,Giuseppe
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Radiologia Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134
Resumo: Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity.
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spelling Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomographyFatty liverSteatosisLiver diseaseTomographyMultidetector computed tomographyContrast media Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity. Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134Radiologia Brasileira v.46 n.3 2013reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/S0100-39842013000300005info:eu-repo/semantics/openAccessMonjardim,Rodrigo da FonsecaCosta,Danilo Manuel CerqueiraRomano,Ricardo Francisco TavaresSalvadori,Priscila SilveiraSantos,Jaime de Vargas Conde dosAtzingen,Augusto Castelli VonShigueoka,David CarlosD'Ippolito,Giuseppeeng2015-09-03T00:00:00Zoai:scielo:S0100-39842013000300134Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2015-09-03T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false
dc.title.none.fl_str_mv Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
title Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
spellingShingle Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
Monjardim,Rodrigo da Fonseca
Fatty liver
Steatosis
Liver disease
Tomography
Multidetector computed tomography
Contrast media
title_short Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
title_full Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
title_fullStr Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
title_full_unstemmed Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
title_sort Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
author Monjardim,Rodrigo da Fonseca
author_facet Monjardim,Rodrigo da Fonseca
Costa,Danilo Manuel Cerqueira
Romano,Ricardo Francisco Tavares
Salvadori,Priscila Silveira
Santos,Jaime de Vargas Conde dos
Atzingen,Augusto Castelli Von
Shigueoka,David Carlos
D'Ippolito,Giuseppe
author_role author
author2 Costa,Danilo Manuel Cerqueira
Romano,Ricardo Francisco Tavares
Salvadori,Priscila Silveira
Santos,Jaime de Vargas Conde dos
Atzingen,Augusto Castelli Von
Shigueoka,David Carlos
D'Ippolito,Giuseppe
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Monjardim,Rodrigo da Fonseca
Costa,Danilo Manuel Cerqueira
Romano,Ricardo Francisco Tavares
Salvadori,Priscila Silveira
Santos,Jaime de Vargas Conde dos
Atzingen,Augusto Castelli Von
Shigueoka,David Carlos
D'Ippolito,Giuseppe
dc.subject.por.fl_str_mv Fatty liver
Steatosis
Liver disease
Tomography
Multidetector computed tomography
Contrast media
topic Fatty liver
Steatosis
Liver disease
Tomography
Multidetector computed tomography
Contrast media
description Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity.
publishDate 2013
dc.date.none.fl_str_mv 2013-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-39842013000300005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
dc.source.none.fl_str_mv Radiologia Brasileira v.46 n.3 2013
reponame:Radiologia Brasileira (Online)
instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
instname_str Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron_str CBR
institution CBR
reponame_str Radiologia Brasileira (Online)
collection Radiologia Brasileira (Online)
repository.name.fl_str_mv Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
repository.mail.fl_str_mv radiologiabrasileira@cbr.org.br
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