Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134 |
Resumo: | Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity. |
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Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomographyFatty liverSteatosisLiver diseaseTomographyMultidetector computed tomographyContrast media Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity. Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134Radiologia Brasileira v.46 n.3 2013reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/S0100-39842013000300005info:eu-repo/semantics/openAccessMonjardim,Rodrigo da FonsecaCosta,Danilo Manuel CerqueiraRomano,Ricardo Francisco TavaresSalvadori,Priscila SilveiraSantos,Jaime de Vargas Conde dosAtzingen,Augusto Castelli VonShigueoka,David CarlosD'Ippolito,Giuseppeeng2015-09-03T00:00:00Zoai:scielo:S0100-39842013000300134Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2015-09-03T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
title |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
spellingShingle |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography Monjardim,Rodrigo da Fonseca Fatty liver Steatosis Liver disease Tomography Multidetector computed tomography Contrast media |
title_short |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
title_full |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
title_fullStr |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
title_full_unstemmed |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
title_sort |
Diagnosis of hepatic steatosis by contrast-enhanced abdominal computed tomography |
author |
Monjardim,Rodrigo da Fonseca |
author_facet |
Monjardim,Rodrigo da Fonseca Costa,Danilo Manuel Cerqueira Romano,Ricardo Francisco Tavares Salvadori,Priscila Silveira Santos,Jaime de Vargas Conde dos Atzingen,Augusto Castelli Von Shigueoka,David Carlos D'Ippolito,Giuseppe |
author_role |
author |
author2 |
Costa,Danilo Manuel Cerqueira Romano,Ricardo Francisco Tavares Salvadori,Priscila Silveira Santos,Jaime de Vargas Conde dos Atzingen,Augusto Castelli Von Shigueoka,David Carlos D'Ippolito,Giuseppe |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Monjardim,Rodrigo da Fonseca Costa,Danilo Manuel Cerqueira Romano,Ricardo Francisco Tavares Salvadori,Priscila Silveira Santos,Jaime de Vargas Conde dos Atzingen,Augusto Castelli Von Shigueoka,David Carlos D'Ippolito,Giuseppe |
dc.subject.por.fl_str_mv |
Fatty liver Steatosis Liver disease Tomography Multidetector computed tomography Contrast media |
topic |
Fatty liver Steatosis Liver disease Tomography Multidetector computed tomography Contrast media |
description |
Objective To evaluate the diagnostic capacity of abdominal computed tomography in the assessment of hepatic steatosis using the portal phase with a simplified calculation method as compared with the non-contrast-enhanced phase. Materials and Methods In the present study, 150 patients were retrospectively evaluated by means of non-contrast-enhanced and contrast-enhanced computed tomography. One hundred patients had hepatic steatosis and 50 were control subjects. For the diagnosis of hepatic steatosis in the portal phase, the authors considered a result of < 104 HU calculated by the formula [L - 0.3 × (0.75 × P + 0.25 × A)] / 0.7, where L, P and A represent the attenuation of the liver, of the main portal vein and abdominal aorta, respectively. Sensitivity, specificity, positive and negative predictive values were calculated, using non-contrast-enhanced computed tomography as the reference standard. Results The simplified calculation method with portal phase for the diagnosis of hepatic steatosis showed 100% sensitivity, 36% specificity, negative predictive value of 100% and positive predictive value of 75.8%. The rate of false positive results was 64%. False negative results were not observed. Conclusion The portal phase presents an excellent sensitivity in the diagnosis of hepatic steatosis, as compared with the non-contrast-enhanced phase of abdominal computed tomography. However, the method has low specificity. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000300134 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-39842013000300005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.46 n.3 2013 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208938432135168 |