Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351 |
Resumo: | Abstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH. |
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Radiologia Brasileira (Online) |
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Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertensionHypertension, pulmonaryTomography, X-ray computedImage processing, computer-assistedAbstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351Radiologia Brasileira v.50 n.6 2017reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2016.0163info:eu-repo/semantics/openAccessWada,Danilo TadaoPádua,Adriana Ignácio deLima Filho,Moyses OliveiraMarin Neto,José AntonioElias Júnior,JorgeBaddini-Martinez,JoséSantos,Marcel Koenigkameng2018-01-05T00:00:00Zoai:scielo:S0100-39842017000600351Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2018-01-05T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
title |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
spellingShingle |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension Wada,Danilo Tadao Hypertension, pulmonary Tomography, X-ray computed Image processing, computer-assisted |
title_short |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
title_full |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
title_fullStr |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
title_full_unstemmed |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
title_sort |
Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension |
author |
Wada,Danilo Tadao |
author_facet |
Wada,Danilo Tadao Pádua,Adriana Ignácio de Lima Filho,Moyses Oliveira Marin Neto,José Antonio Elias Júnior,Jorge Baddini-Martinez,José Santos,Marcel Koenigkam |
author_role |
author |
author2 |
Pádua,Adriana Ignácio de Lima Filho,Moyses Oliveira Marin Neto,José Antonio Elias Júnior,Jorge Baddini-Martinez,José Santos,Marcel Koenigkam |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Wada,Danilo Tadao Pádua,Adriana Ignácio de Lima Filho,Moyses Oliveira Marin Neto,José Antonio Elias Júnior,Jorge Baddini-Martinez,José Santos,Marcel Koenigkam |
dc.subject.por.fl_str_mv |
Hypertension, pulmonary Tomography, X-ray computed Image processing, computer-assisted |
topic |
Hypertension, pulmonary Tomography, X-ray computed Image processing, computer-assisted |
description |
Abstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0100-3984.2016.0163 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.50 n.6 2017 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208939376902144 |