Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension

Detalhes bibliográficos
Autor(a) principal: Wada,Danilo Tadao
Data de Publicação: 2017
Outros Autores: Pádua,Adriana Ignácio de, Lima Filho,Moyses Oliveira, Marin Neto,José Antonio, Elias Júnior,Jorge, Baddini-Martinez,José, Santos,Marcel Koenigkam
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Radiologia Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351
Resumo: Abstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH.
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spelling Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertensionHypertension, pulmonaryTomography, X-ray computedImage processing, computer-assistedAbstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351Radiologia Brasileira v.50 n.6 2017reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2016.0163info:eu-repo/semantics/openAccessWada,Danilo TadaoPádua,Adriana Ignácio deLima Filho,Moyses OliveiraMarin Neto,José AntonioElias Júnior,JorgeBaddini-Martinez,JoséSantos,Marcel Koenigkameng2018-01-05T00:00:00Zoai:scielo:S0100-39842017000600351Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2018-01-05T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false
dc.title.none.fl_str_mv Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
title Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
spellingShingle Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
Wada,Danilo Tadao
Hypertension, pulmonary
Tomography, X-ray computed
Image processing, computer-assisted
title_short Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
title_full Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
title_fullStr Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
title_full_unstemmed Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
title_sort Use of computed tomography and automated software for quantitative analysis of the vasculature of patients with pulmonary hypertension
author Wada,Danilo Tadao
author_facet Wada,Danilo Tadao
Pádua,Adriana Ignácio de
Lima Filho,Moyses Oliveira
Marin Neto,José Antonio
Elias Júnior,Jorge
Baddini-Martinez,José
Santos,Marcel Koenigkam
author_role author
author2 Pádua,Adriana Ignácio de
Lima Filho,Moyses Oliveira
Marin Neto,José Antonio
Elias Júnior,Jorge
Baddini-Martinez,José
Santos,Marcel Koenigkam
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Wada,Danilo Tadao
Pádua,Adriana Ignácio de
Lima Filho,Moyses Oliveira
Marin Neto,José Antonio
Elias Júnior,Jorge
Baddini-Martinez,José
Santos,Marcel Koenigkam
dc.subject.por.fl_str_mv Hypertension, pulmonary
Tomography, X-ray computed
Image processing, computer-assisted
topic Hypertension, pulmonary
Tomography, X-ray computed
Image processing, computer-assisted
description Abstract Objective: To perform a quantitative analysis of the lung parenchyma and pulmonary vasculature of patients with pulmonary hypertension (PH) on computed tomography angiography (CTA) images, using automated software. Materials and Methods: We retrospectively analyzed the CTA findings and clinical records of 45 patients with PH (17 males and 28 females), in comparison with a control group of 20 healthy individuals (7 males and 13 females); the mean age differed significantly between the two groups (53 ± 14.7 vs. 35 ± 9.6 years; p = 0.0001). Results: The automated analysis showed that, in comparison with the controls, the patients with PH showed lower 10th percentile values for lung density, higher vascular volumes in the right upper lung lobe, and higher vascular volume ratios between the upper and lower lobes. In our quantitative analysis, we found no differences among the various PH subgroups. We inferred that a difference in the 10th percentile values indicates areas of hypovolemia in patients with PH and that a difference in pulmonary vascular volumes indicates redistribution of the pulmonary vasculature and an increase in pulmonary vasculature resistance. Conclusion: Automated analysis of pulmonary vessels on CTA images revealed alterations and could represent an objective diagnostic tool for the evaluation of patients with PH.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017000600351
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0100-3984.2016.0163
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
dc.source.none.fl_str_mv Radiologia Brasileira v.50 n.6 2017
reponame:Radiologia Brasileira (Online)
instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
instname_str Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron_str CBR
institution CBR
reponame_str Radiologia Brasileira (Online)
collection Radiologia Brasileira (Online)
repository.name.fl_str_mv Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
repository.mail.fl_str_mv radiologiabrasileira@cbr.org.br
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