The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842015000100011 |
Resumo: | Recent studies have demonstrated that the use of paramagnetic hepatobiliary contrast agents in the acquisition of magnetic resonance images remarkably improves the detection and differentiation of focal liver lesions, as compared with extracellular contrast agents. Paramagnetic hepatobiliary contrast agents initially show the perfusion of the lesions, as do extracellular agents, but delayed contrast-enhanced images can demonstrate contrast uptake by functional hepatocytes, providing further information for a better characterization of the lesions. Additionally, this intrinsic characteristic increases the accuracy in the detection of hepatocellular carcinomas and metastases, particularly the small-sized ones. Recently, a hepatobiliary contrast agent called gadolinium ethoxybenzyl dimeglumine, that is simply known as gadoxetic acid, was approved by the National Health Surveillance Agency for use in humans. The authors present a literature review and a practical approach of magnetic resonance imaging utilizing gadoxetic acid as contrast agent, based on patients' images acquired during their initial experiment. |
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Radiologia Brasileira (Online) |
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The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a reviewMagnetic resonance imagingGadoliniumLiverContrast mediaRecent studies have demonstrated that the use of paramagnetic hepatobiliary contrast agents in the acquisition of magnetic resonance images remarkably improves the detection and differentiation of focal liver lesions, as compared with extracellular contrast agents. Paramagnetic hepatobiliary contrast agents initially show the perfusion of the lesions, as do extracellular agents, but delayed contrast-enhanced images can demonstrate contrast uptake by functional hepatocytes, providing further information for a better characterization of the lesions. Additionally, this intrinsic characteristic increases the accuracy in the detection of hepatocellular carcinomas and metastases, particularly the small-sized ones. Recently, a hepatobiliary contrast agent called gadolinium ethoxybenzyl dimeglumine, that is simply known as gadoxetic acid, was approved by the National Health Surveillance Agency for use in humans. The authors present a literature review and a practical approach of magnetic resonance imaging utilizing gadoxetic acid as contrast agent, based on patients' images acquired during their initial experiment.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2015-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842015000100011Radiologia Brasileira v.48 n.1 2015reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2013.1794info:eu-repo/semantics/openAccessBormann,Renata LilianRocha,Eduardo Lima daKierzenbaum,Marcelo LongoPedrassa,Bruno CheregatiTorres,Lucas RiosD'Ippolito,Giuseppeeng2015-04-14T00:00:00Zoai:scielo:S0100-39842015000100011Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2015-04-14T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
title |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
spellingShingle |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review Bormann,Renata Lilian Magnetic resonance imaging Gadolinium Liver Contrast media |
title_short |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
title_full |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
title_fullStr |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
title_full_unstemmed |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
title_sort |
The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review |
author |
Bormann,Renata Lilian |
author_facet |
Bormann,Renata Lilian Rocha,Eduardo Lima da Kierzenbaum,Marcelo Longo Pedrassa,Bruno Cheregati Torres,Lucas Rios D'Ippolito,Giuseppe |
author_role |
author |
author2 |
Rocha,Eduardo Lima da Kierzenbaum,Marcelo Longo Pedrassa,Bruno Cheregati Torres,Lucas Rios D'Ippolito,Giuseppe |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Bormann,Renata Lilian Rocha,Eduardo Lima da Kierzenbaum,Marcelo Longo Pedrassa,Bruno Cheregati Torres,Lucas Rios D'Ippolito,Giuseppe |
dc.subject.por.fl_str_mv |
Magnetic resonance imaging Gadolinium Liver Contrast media |
topic |
Magnetic resonance imaging Gadolinium Liver Contrast media |
description |
Recent studies have demonstrated that the use of paramagnetic hepatobiliary contrast agents in the acquisition of magnetic resonance images remarkably improves the detection and differentiation of focal liver lesions, as compared with extracellular contrast agents. Paramagnetic hepatobiliary contrast agents initially show the perfusion of the lesions, as do extracellular agents, but delayed contrast-enhanced images can demonstrate contrast uptake by functional hepatocytes, providing further information for a better characterization of the lesions. Additionally, this intrinsic characteristic increases the accuracy in the detection of hepatocellular carcinomas and metastases, particularly the small-sized ones. Recently, a hepatobiliary contrast agent called gadolinium ethoxybenzyl dimeglumine, that is simply known as gadoxetic acid, was approved by the National Health Surveillance Agency for use in humans. The authors present a literature review and a practical approach of magnetic resonance imaging utilizing gadoxetic acid as contrast agent, based on patients' images acquired during their initial experiment. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842015000100011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842015000100011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0100-3984.2013.1794 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.48 n.1 2015 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208938863099904 |