ANTIBACTERIAL ACIVITY OF GOLD AND SILVER NANOPARTICLES IMPREGNATED WITH ANTIMICROBIAL AGENTS

• Autor(a) principal: Savi, Geovana Dagostim
• Data de Publicação: 2013
• Outros Autores: Trombin, Ana Cláudia, Generoso, Jaqueline da Silva, Barichello, Tatiana, Possato, Jonathann Correa, Ronconi, João Vitor Vieira, Paula, Marcos Marques da Silva
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde e Pesquisa (Online)
• Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2676
• topic: Nanoparticles; Antimicrobial Agents; Synergism; Microorganisms; Antimicrobianos; Micro-organismos; Nanopartículas; Sinergismo; .

Introduction: The bactericidal activity of Ag-NPs and Au-NPs impregnated with ceftriaxone, rifampicin and vancomycin is evalauted. Results: Ag-NPs impregnated with rifampicin, vancomycin and ceftriaxone showed a respective inhibition zone of 15.0 mm, 11.3 mm and 26.0 mm to E.coli. Whereas Au-NPs impregnated with rifampicin and vancomycin showed a non inhibition zone, ceftriaxone showed a zone of 27.0 mm. When Ag-NPs were impregnated with rifampicin, vancomycin and ceftriaxone, they showed a zone of 10.0 mm against P. aeruginosa, but Au-NPs showed a non inhibition zone. When Ag-NPs were impregnated against S. aureus with rifampicin, vancomycin and ceftriaxone, they showed an inhibition zone of 36.7 mm, 18.0 mm and 10.0 mm, respectively. When Au-NPs were impregnated with vancomycin, rifampicin and ceftriaxone, they showed an inhibition zone respectively of 36.0 mm, 18.0 mm and 13.3 mm. Conclusion: Results showed that the efficiency of the nanoparticles impregnated with antibiotics may depend on the antibiotics used.