METFORMIN: A REVIEW OF THE LITERATURE
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2015 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Saúde e Pesquisa (Online) |
| Texto Completo: | https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4105 |
Resumo: | Metformin, commercialized under several trademarks and also as a generic medicine, is an oral anti-diabetic drug, belonging to the biguanide class. It is actually the first choice in the treatment of Type 2 diabetes mellitus (DM2) due to its toxicity and clinical efficaciousness. It extensive use requires a constant discussion on its characteristics and applications. Current paper is a bibliographical review comprising the application of metformin in DM2 treatment as its chemical, physical-chemical, pharmacokinetic, pharmacodynamics properties, its clinical usages, contraindications and side effects. Review occurred in Pubmed, Bireme, Lilacs and SciELO data banks and in research in journals published on the Brazilian Platform in Scientific Information and in books on the subject. Results show that metformin is the best medicine for diabetic patients, with auxiliary therapy for other physiological disorders. |
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METFORMIN: A REVIEW OF THE LITERATUREMetformina: Uma Revisão da LiteraturaBiguanidesDiabetes Mellitus type 2MetforminBiguanidasDiabetes mellitus tipo 2MetforminaMetformin, commercialized under several trademarks and also as a generic medicine, is an oral anti-diabetic drug, belonging to the biguanide class. It is actually the first choice in the treatment of Type 2 diabetes mellitus (DM2) due to its toxicity and clinical efficaciousness. It extensive use requires a constant discussion on its characteristics and applications. Current paper is a bibliographical review comprising the application of metformin in DM2 treatment as its chemical, physical-chemical, pharmacokinetic, pharmacodynamics properties, its clinical usages, contraindications and side effects. Review occurred in Pubmed, Bireme, Lilacs and SciELO data banks and in research in journals published on the Brazilian Platform in Scientific Information and in books on the subject. Results show that metformin is the best medicine for diabetic patients, with auxiliary therapy for other physiological disorders.A metformina, medicamento comercializado por diversas marcas e também na forma de genérico, é um antidiabético oral pertencente à classe das biguanidas. Devido ao seu perfil de toxicidade e à sua eficácia clínica é a principal escolha no tratamento do diabetes mellitus tipo dois (DM2). Pelo seu grande uso é necessária uma discussão constante a respeito de suas características e aplicações. Objetivou-se realizar uma revisão bibliográfica, na qual serão abordadas a aplicação da metformina no tratamento de DM2 bem como suas propriedades químicas, físico-químicas, farmacocinéticas, farmacodinâmicas, seus usos clínicos, contraindicações e efeitos adversos. Revisão da literatura realizada nos bancos de dados Pubmed, Bireme, Lilacs e Scielo, bem como pesquisa nos periódicos do Portal Brasileiro da Informação Científica e livros sobre o assunto. Pelo exposto percebe-se que a metformina para pacientes diabéticos é considerada um fármaco ideal tendo ainda aplicações na terapêutica adjuvante de outros distúrbios fisiológicos.Universidade Cesumar - UniCesumar2015-09-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/410510.17765/1983-1870.2015v8n2p355-362Saúde e Pesquisa; Vol 8 No 2 (2015): maio/ago.; 355-362Saúde e Pesquisa; v. 8 n. 2 (2015): maio/ago.; 355-3622176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4105/2641Rodrigues Neto, Edilson MartinsMarques, Lidia Audrey Rocha ValadasFerreira, Maria Augusta DragoLobo, Patricia Leal DantasGirão Junior, Francisco JosimarCamarão, Gisela CostaMoraes, Maria Elisabete Amaral deinfo:eu-repo/semantics/openAccess2021-12-09T11:28:50Zoai:ojs.pkp.sfu.ca:article/4105Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2021-12-09T11:28:50Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse |
| dc.title.none.fl_str_mv |
METFORMIN: A REVIEW OF THE LITERATURE Metformina: Uma Revisão da Literatura |
| title |
METFORMIN: A REVIEW OF THE LITERATURE |
| spellingShingle |
METFORMIN: A REVIEW OF THE LITERATURE Rodrigues Neto, Edilson Martins Biguanides Diabetes Mellitus type 2 Metformin Biguanidas Diabetes mellitus tipo 2 Metformina |
| title_short |
METFORMIN: A REVIEW OF THE LITERATURE |
| title_full |
METFORMIN: A REVIEW OF THE LITERATURE |
| title_fullStr |
METFORMIN: A REVIEW OF THE LITERATURE |
| title_full_unstemmed |
METFORMIN: A REVIEW OF THE LITERATURE |
| title_sort |
METFORMIN: A REVIEW OF THE LITERATURE |
| author |
Rodrigues Neto, Edilson Martins |
| author_facet |
Rodrigues Neto, Edilson Martins Marques, Lidia Audrey Rocha Valadas Ferreira, Maria Augusta Drago Lobo, Patricia Leal Dantas Girão Junior, Francisco Josimar Camarão, Gisela Costa Moraes, Maria Elisabete Amaral de |
| author_role |
author |
| author2 |
Marques, Lidia Audrey Rocha Valadas Ferreira, Maria Augusta Drago Lobo, Patricia Leal Dantas Girão Junior, Francisco Josimar Camarão, Gisela Costa Moraes, Maria Elisabete Amaral de |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Rodrigues Neto, Edilson Martins Marques, Lidia Audrey Rocha Valadas Ferreira, Maria Augusta Drago Lobo, Patricia Leal Dantas Girão Junior, Francisco Josimar Camarão, Gisela Costa Moraes, Maria Elisabete Amaral de |
| dc.subject.por.fl_str_mv |
Biguanides Diabetes Mellitus type 2 Metformin Biguanidas Diabetes mellitus tipo 2 Metformina |
| topic |
Biguanides Diabetes Mellitus type 2 Metformin Biguanidas Diabetes mellitus tipo 2 Metformina |
| description |
Metformin, commercialized under several trademarks and also as a generic medicine, is an oral anti-diabetic drug, belonging to the biguanide class. It is actually the first choice in the treatment of Type 2 diabetes mellitus (DM2) due to its toxicity and clinical efficaciousness. It extensive use requires a constant discussion on its characteristics and applications. Current paper is a bibliographical review comprising the application of metformin in DM2 treatment as its chemical, physical-chemical, pharmacokinetic, pharmacodynamics properties, its clinical usages, contraindications and side effects. Review occurred in Pubmed, Bireme, Lilacs and SciELO data banks and in research in journals published on the Brazilian Platform in Scientific Information and in books on the subject. Results show that metformin is the best medicine for diabetic patients, with auxiliary therapy for other physiological disorders. |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015-09-28 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4105 10.17765/1983-1870.2015v8n2p355-362 |
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https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4105 |
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10.17765/1983-1870.2015v8n2p355-362 |
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por |
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por |
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https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4105/2641 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Cesumar - UniCesumar |
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Universidade Cesumar - UniCesumar |
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Saúde e Pesquisa; Vol 8 No 2 (2015): maio/ago.; 355-362 Saúde e Pesquisa; v. 8 n. 2 (2015): maio/ago.; 355-362 2176-9206 reponame:Saúde e Pesquisa (Online) instname:Cesumar Diretoria de Pesquisa instacron:CESUMAR |
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Cesumar Diretoria de Pesquisa |
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CESUMAR |
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CESUMAR |
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Saúde e Pesquisa (Online) |
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Saúde e Pesquisa (Online) |
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Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa |
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naep@cesumar.br |
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