Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta

Detalhes bibliográficos
Autor(a) principal: Travain, Willian
Data de Publicação: 2015
Outros Autores: Santos, Hanna Carolina Bet Dos, Carrascoza, Valéria Schoffen Romao, Brito, Márcia do Nascimento, Godoy Gomes, Célia Regina
Tipo de documento: Artigo
Idioma: por
Título da fonte: Saúde e Pesquisa (Online)
Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/3914
Resumo: Current study analyzes the influence of coconut oil on the morphology of the thorax aorta in 23 rats aged 120 days. The animals were separated into two groups, control (treated with standard ration for rodents) and obese (treated with a hypercaloric diet to induce obesity). After 90 days the control and obese groups were subdivided into two additional groups: C/ag, C/co, O/ag, O/co. On the 120th day the rats were euthanized with sodium pentobarbitol. The thorax aortas were removed and histologically processed. They were stained with Masson Trichromium and orcein-picrosirius-hematoxylin to visualize collagen components, smooth and elastic muscle, followed by volume density. Vessel thickness was evaluated by intima-media measure. Analysis of variance (ANOVA) and Tukey´s test were employed at 5% significance. The use of coconut oil in obese rats may have induced vascular re-modeling by decreasing the composition of collagen and increasing the smooth muscle cells in obese rats treated with coconut oil.
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spelling Effects of Coconut Oil on the Morphology of Obese Rats´ AortaEfeito do Óleo de Coco sobre a Morfologia da Aorta de Ratos ObesosThorax AortaCoconutsVegetal FatHistologyObesity.Aorta TorácicaCocosGorduras VegetaisHistologiaObesidadeThorax AortaCoconutsVegetal FatHistologyObesityCurrent study analyzes the influence of coconut oil on the morphology of the thorax aorta in 23 rats aged 120 days. The animals were separated into two groups, control (treated with standard ration for rodents) and obese (treated with a hypercaloric diet to induce obesity). After 90 days the control and obese groups were subdivided into two additional groups: C/ag, C/co, O/ag, O/co. On the 120th day the rats were euthanized with sodium pentobarbitol. The thorax aortas were removed and histologically processed. They were stained with Masson Trichromium and orcein-picrosirius-hematoxylin to visualize collagen components, smooth and elastic muscle, followed by volume density. Vessel thickness was evaluated by intima-media measure. Analysis of variance (ANOVA) and Tukey´s test were employed at 5% significance. The use of coconut oil in obese rats may have induced vascular re-modeling by decreasing the composition of collagen and increasing the smooth muscle cells in obese rats treated with coconut oil.O objetivo desse estudo foi avaliar a influência do óleo de coco sobre morfologia da aorta torácica. Foram utilizados 23 animais, com 120 dias de idade. Os animais foram inicialmente separados em dois grupos, controle (tratado com dieta padrão para roedores) e obeso (tratado com dieta hipercalórica para induzir a obesidade). Aos 90 dias, os animais dos grupos controle e obeso foram subdivididos em dois grupos adicionais: C/ag, C/co, O/ag, O/co. Aos 120 dias foram eutanasiados com pentobarbitol sódico. As aortas torácicas extraídas foram processadas histologicamente e coradas com Tricrômico de Masson e Orceína-picrussírus-hematoxilina para visualização dos componentes colágeno, músculo liso e elástico, seguida da quantificação realizada por densidade de volume. Realizou-se a medida íntima-média, para verificação da espessura do vaso. A estatística seguiu Análise de Variância de um fator (ANOVA), seguida pelo teste de Tukey, para nível de significância de 5%. Concluímos que a utilização de óleo de coco em ratos obesos parece induzir uma remodelação vascular marcada pela diminuição na composição de colágeno e aumento de células musculares lisas em ratos obesos tratados com óleo de coco. Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta ABSTRACT: Current study analyzes the influence of coconut oil on the morphology of the thorax aorta in 23 rats aged 120 days. The animals were separated into two groups, control (treated with standard ration for rodents) and obese (treated with a hypercaloric diet to induce obesity). After 90 days the control and obese groups were subdivided into two additional groups: C/ag, C/co, O/ag, O/co. On the 120th day the rats were euthanized with sodium pentobarbitol. The thorax aortas were removed and histologically processed. They were stained with Masson Trichromium and orcein-picrosirius-hematoxylin to visualize collagen components, smooth and elastic muscle, followed by volume density. Vessel thickness was evaluated by intima-media measure. Analysis of variance (ANOVA) and Tukey´s test were employed at 5% significance. The use of coconut oil in obese rats may have induced vascular re-modeling by decreasing the composition of collagen and increasing the smooth muscle cells in obese rats treated with coconut oil.Universidade Cesumar - UniCesumar2015-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por Paresapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/391410.17765/1983-1870.2015v8n1p35-43Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 35-43Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 35-432176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/3914/2552Travain, WillianSantos, Hanna Carolina Bet DosCarrascoza, Valéria Schoffen RomaoBrito, Márcia do NascimentoGodoy Gomes, Célia Reginainfo:eu-repo/semantics/openAccess2021-03-24T20:09:25Zoai:ojs.pkp.sfu.ca:article/3914Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2021-03-24T20:09:25Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse
dc.title.none.fl_str_mv Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
Efeito do Óleo de Coco sobre a Morfologia da Aorta de Ratos Obesos
title Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
spellingShingle Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
Travain, Willian
Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity.
Aorta Torácica
Cocos
Gorduras Vegetais
Histologia
Obesidade
Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity
title_short Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
title_full Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
title_fullStr Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
title_full_unstemmed Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
title_sort Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta
author Travain, Willian
author_facet Travain, Willian
Santos, Hanna Carolina Bet Dos
Carrascoza, Valéria Schoffen Romao
Brito, Márcia do Nascimento
Godoy Gomes, Célia Regina
author_role author
author2 Santos, Hanna Carolina Bet Dos
Carrascoza, Valéria Schoffen Romao
Brito, Márcia do Nascimento
Godoy Gomes, Célia Regina
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Travain, Willian
Santos, Hanna Carolina Bet Dos
Carrascoza, Valéria Schoffen Romao
Brito, Márcia do Nascimento
Godoy Gomes, Célia Regina
dc.subject.por.fl_str_mv Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity.
Aorta Torácica
Cocos
Gorduras Vegetais
Histologia
Obesidade
Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity
topic Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity.
Aorta Torácica
Cocos
Gorduras Vegetais
Histologia
Obesidade
Thorax Aorta
Coconuts
Vegetal Fat
Histology
Obesity
description Current study analyzes the influence of coconut oil on the morphology of the thorax aorta in 23 rats aged 120 days. The animals were separated into two groups, control (treated with standard ration for rodents) and obese (treated with a hypercaloric diet to induce obesity). After 90 days the control and obese groups were subdivided into two additional groups: C/ag, C/co, O/ag, O/co. On the 120th day the rats were euthanized with sodium pentobarbitol. The thorax aortas were removed and histologically processed. They were stained with Masson Trichromium and orcein-picrosirius-hematoxylin to visualize collagen components, smooth and elastic muscle, followed by volume density. Vessel thickness was evaluated by intima-media measure. Analysis of variance (ANOVA) and Tukey´s test were employed at 5% significance. The use of coconut oil in obese rats may have induced vascular re-modeling by decreasing the composition of collagen and increasing the smooth muscle cells in obese rats treated with coconut oil.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/3914
10.17765/1983-1870.2015v8n1p35-43
url https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/3914
identifier_str_mv 10.17765/1983-1870.2015v8n1p35-43
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/3914/2552
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
dc.source.none.fl_str_mv Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 35-43
Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 35-43
2176-9206
reponame:Saúde e Pesquisa (Online)
instname:Cesumar Diretoria de Pesquisa
instacron:CESUMAR
instname_str Cesumar Diretoria de Pesquisa
instacron_str CESUMAR
institution CESUMAR
reponame_str Saúde e Pesquisa (Online)
collection Saúde e Pesquisa (Online)
repository.name.fl_str_mv Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa
repository.mail.fl_str_mv naep@cesumar.br
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