Complications of herpes zoster hospitalizations in a reference hospital in Fortaleza-Ceará, 2009-2018

• Autor(a) principal: Barbosa, Patrícia Pereira Limas
• Data de Publicação: 2022
• Outros Autores: Florêncio, Caroline Mary Gurgel Dias, Alencar, Carlos Henrique
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of Health & Biological Sciences
• Texto Completo: https://periodicos.unichristus.edu.br/jhbs/article/view/4244
• topic: Herpes zoster; Varicella Zoster Virus Infection; Epidemiology; Risk factors

Objective: the aim of this study was to relate sociodemographic, epidemiological and clinical conditions to the occurrence of severe cases of HZ in reference hospital of Fortaleza. Methods: this is a cross-sectional analytical study, based on medical records of patients admitted from 2009 to 2018. Pearson's x2 test or Fisher's exact test were used when appropriate. Results: we analyzed 196 medical records. The presence of complications occurred in 69.9%, the most affected region was the cranial (68.9%), and 1.5% died. The presence of vesicles (PR=1.37; 95%CI: 1.03-1.82; p=0.01) and the choice of antibiotic associated antiviral therapy (PR=0.58; 95%CI: 0.46-0.73; p=0.00) were significantly associated with the severity. Conclusions: the disease may be more severe at ages over 50. The presence of lesions in vesicles was associated with a higher prevalence of complications and the use of antibiotics and antivirals as a protective factor.