Profile.

• Autor(a) principal: Batista, Bruna Gerardon
• Data de Publicação: 2016
• Outros Autores: Alves d' Azevedo, Pedro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of Health & Biological Sciences
• Texto Completo: https://periodicos.unichristus.edu.br/jhbs/article/view/514
• topic: Methicillin-Resistant Staphylococcus aureus; Molecular Typing; Polymerase Chain Reaction; Methicillin-Resistant Staphylococcus aureus; Molecular Typing; Polymerase Chain Reaction

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen that affects public health representing the most common infections related to health care and community. MRSA infections are classified as health care-associated MRSA (HA-MRSA) and community-associated MRSA (CA-MRSA) defined by the bacteria genetic profile. Objective: This study conducts a molecular characterization of MRSA isolates from a hospital in Porto Alegre, RS, Brazil, in order to determine the profile of SCCmec types. Methods: Eighty-one MRSA isolates from a hospital in Porto Alegre, RS, Brazil, collected from January to June of 2012 were included in the study. A multiplex PCR was performed to determine the SCCmec types. Results: From the 81 isolates, 24 (30%) were type I, 10 (12%) type II, 21 (26%) type III, 4 (5%) type IVa, 12 (15%) isolates were type IVc, 1 isolate was type I and IVc (1%) and 1 was type III and IVc (1%) simultaneously, while non-typable isolates corresponded to 8 isolates (10%). Conclusion: However most of the isolates were carrying SCCmec types related to HA-MRSA; the results reveal a change in the epidemiology, considering the decrease of the incidence of SCCmec type III and the increase of isolates being typed as SCCmec I.