PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT

• Autor(a) principal: da Silva, Léa Assed Bezerra
• Data de Publicação: 2019
• Outros Autores: Araujo, Lisa Danielly Curcino, Fierro, Marcela Martín del Campo, de Paula-Silva, Francisco Wanderley Garcia, da Silva, Raquel Assed Bezerra, Nelson Filho, Paulo, Consolaro, Alberto, Leonardo, Mário Roberto
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica do CRO-RJ (Online)
• Texto Completo: https://cro-rj.org.br/revcientifica/index.php/revista/article/view/98
• topic: Pulpotomy; Dental Enamel; Calcium hydroxide; Zinc oxide and eugenol

Objective: To evaluate the pulpal and periapical response of dogs’ teeth after pulpotomy and use of Enamel Matrix Derivative (EMD) as capping agent. Methods: Pulpotomy was performed in 40 teeth from 4 dogs and the remaining pulp tissue was recovered with the following materials: Groups I and IV: EMD (Emdogain®); Groups II and V: calcium hydroxide; Groups III and VI: zinc oxide and eugenol cement. After 7 days (Groups I, II, and III) and 70 days (Groups IV, V, and VI), the animals were euthanized and the teeth were removed and processed for histological analysis; were analyzed using Kruskal-Wallis test followed by Dunn test or Mann Whitney test ( =0.05). Results: 7-day period: in Group I, it was observed a mild to moderate inflammatory infiltrate and intense vascular proliferation while Group II presented a mild inflammatory infiltrate and an intact pulp tissue (p < 0.05). Group III presented a moderate to severe inflammatory infiltrate. 70-day period: Groups IV and VI showed no dentin bridge formation, the remaining pulp tissue presented necrotic areas with inflammatory cells in the periapical region and bone and cementum resorption (p > 0.05). In Group V, there was dentin bridge formation, absence of inflammation and absence of mineralized tissue resorption (p < 0.05). Conclusion: EMD as a capping material after pulpotomy did not show either satisfactory tissue response or capacity of inducing deposition of mineralized tissue in dental pulp.