PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT

Detalhes bibliográficos
Autor(a) principal: da Silva, Léa Assed Bezerra
Data de Publicação: 2019
Outros Autores: Araujo, Lisa Danielly Curcino, Fierro, Marcela Martín del Campo, de Paula-Silva, Francisco Wanderley Garcia, da Silva, Raquel Assed Bezerra, Nelson Filho, Paulo, Consolaro, Alberto, Leonardo, Mário Roberto
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Científica do CRO-RJ (Online)
DOI: 10.29327/24816.4.2-3
Texto Completo: https://cro-rj.org.br/revcientifica/index.php/revista/article/view/98
Resumo: Objective: To evaluate the pulpal and periapical response of dogs’ teeth after pulpotomy and use of Enamel Matrix Derivative (EMD) as capping agent. Methods: Pulpotomy was performed in 40 teeth from 4 dogs and the remaining pulp tissue was recovered with the following materials: Groups I and IV: EMD (Emdogain®); Groups II and V: calcium hydroxide; Groups III and VI: zinc oxide and eugenol cement. After 7 days (Groups I, II, and III) and 70 days (Groups IV, V, and VI), the animals were euthanized and the teeth were removed and processed for histological analysis; were analyzed using Kruskal-Wallis test followed by Dunn test or Mann Whitney test ( =0.05). Results: 7-day period: in Group I, it was observed a mild to moderate inflammatory infiltrate and intense vascular proliferation while Group II presented a mild inflammatory infiltrate and an intact pulp tissue (p < 0.05). Group III presented a moderate to severe inflammatory infiltrate. 70-day period: Groups IV and VI showed no dentin bridge formation, the remaining pulp tissue presented necrotic areas with inflammatory cells in the periapical region and bone and cementum resorption (p > 0.05). In Group V, there was dentin bridge formation, absence of inflammation and absence of mineralized tissue resorption (p < 0.05). Conclusion: EMD as a capping material after pulpotomy did not show either satisfactory tissue response or capacity of inducing deposition of mineralized tissue in dental pulp.
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spelling PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENTPULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENTPulpotomyDental EnamelCalcium hydroxideZinc oxide and eugenolObjective: To evaluate the pulpal and periapical response of dogs’ teeth after pulpotomy and use of Enamel Matrix Derivative (EMD) as capping agent. Methods: Pulpotomy was performed in 40 teeth from 4 dogs and the remaining pulp tissue was recovered with the following materials: Groups I and IV: EMD (Emdogain®); Groups II and V: calcium hydroxide; Groups III and VI: zinc oxide and eugenol cement. After 7 days (Groups I, II, and III) and 70 days (Groups IV, V, and VI), the animals were euthanized and the teeth were removed and processed for histological analysis; were analyzed using Kruskal-Wallis test followed by Dunn test or Mann Whitney test ( =0.05). Results: 7-day period: in Group I, it was observed a mild to moderate inflammatory infiltrate and intense vascular proliferation while Group II presented a mild inflammatory infiltrate and an intact pulp tissue (p < 0.05). Group III presented a moderate to severe inflammatory infiltrate. 70-day period: Groups IV and VI showed no dentin bridge formation, the remaining pulp tissue presented necrotic areas with inflammatory cells in the periapical region and bone and cementum resorption (p > 0.05). In Group V, there was dentin bridge formation, absence of inflammation and absence of mineralized tissue resorption (p < 0.05). Conclusion: EMD as a capping material after pulpotomy did not show either satisfactory tissue response or capacity of inducing deposition of mineralized tissue in dental pulp.Objetivo: Avaliar a resposta pulpar e periapical de dentes de cães após pulpotomia e uso de Derivados de Matriz de Esmalte (EMD) como agente de capeamento. Métodos: A pulpotomia foi realizada em 40 dentes de 4 cães e o tecido pulpar remanescente foi recuperado com os seguintes materiais: Grupos I e IV: EMD (Emdogain®); Grupos II e V: hidróxido de cálcio; Grupos III e VI: cimento de óxido de zinco e eugenol. Após 7 dias (Grupos I, II e III) e 70 dias (Grupos IV, V e VI), os animais foram eutanásiados e os dentes foram removidos e processados para análise histológica; foram analisados pelo teste de Kruskal-Wallis, seguidopelo teste de Dunn ou Mann Whitney ( = 0,05). Resultados: Período de 7 dias: no Grupo I, observou-se infiltrado inflamatório leve a moderado e intensa proliferação vascular, enquanto o Grupo II apresentou infiltrado inflamatório leve e tecido pulpar intacto (p <0,05). O grupo III apresentou infiltrado inflamatório moderado a grave. Período de 70 dias: os grupos IV e VI mostraram, na formação da ponte de dentina, que o tecido pulpar remanescente apresentava áreas necróticas com células inflamatórias na região periapical, reabsorção óssea e de cemento (p>0,05). No Grupo V, houve formação de ponte de dentina, ausência de inflamação e ausência de reabsorção tecidual mineralizada (p <0,05). Conclusão: O EMD como material de cobertura após pulpotomia não mostrou resposta tecidual satisfatória ou capacidade de induzir deposição de tecido mineralizado na polpa dentária.Rio de Janeiro Dental Journal2019-10-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://cro-rj.org.br/revcientifica/index.php/revista/article/view/9810.29327/24816.4.2-3Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); Vol. 4 No. 2: May-August 2019; 12-18Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); v. 4 n. 2: May-August 2019; 12-182595-47331518-524910.29327/24816.4.2reponame:Revista Científica do CRO-RJ (Online)instname:Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)instacron:CROporhttps://cro-rj.org.br/revcientifica/index.php/revista/article/view/98/67Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)info:eu-repo/semantics/openAccessda Silva, Léa Assed BezerraAraujo, Lisa Danielly CurcinoFierro, Marcela Martín del Campode Paula-Silva, Francisco Wanderley Garciada Silva, Raquel Assed BezerraNelson Filho, PauloConsolaro, AlbertoLeonardo, Mário Roberto2019-12-09T18:57:41Zoai:ojs3.cro-rj.org.br:article/98Revistahttps://cro-rj.org.br/revcientifica/index.php/revistahttps://cro-rj.org.br/revcientifica/index.php/revista/oairevista.cientifica@cro-rj.org.br || rorefa@terra.com.br2595-47331518-5249opendoar:2019-12-09T18:57:41Revista Científica do CRO-RJ (Online) - Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)false
dc.title.none.fl_str_mv PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
title PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
spellingShingle PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
da Silva, Léa Assed Bezerra
Pulpotomy
Dental Enamel
Calcium hydroxide
Zinc oxide and eugenol
da Silva, Léa Assed Bezerra
Pulpotomy
Dental Enamel
Calcium hydroxide
Zinc oxide and eugenol
title_short PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
title_full PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
title_fullStr PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
title_full_unstemmed PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
title_sort PULPAL AND PERIAPICAL RESPONSE OF DOGS’ TEETH AFTER PULPOTOMY AND USE OF ENAMEL MATRIX DERIVATIVE AS A CAPPING AGENT
author da Silva, Léa Assed Bezerra
author_facet da Silva, Léa Assed Bezerra
da Silva, Léa Assed Bezerra
Araujo, Lisa Danielly Curcino
Fierro, Marcela Martín del Campo
de Paula-Silva, Francisco Wanderley Garcia
da Silva, Raquel Assed Bezerra
Nelson Filho, Paulo
Consolaro, Alberto
Leonardo, Mário Roberto
Araujo, Lisa Danielly Curcino
Fierro, Marcela Martín del Campo
de Paula-Silva, Francisco Wanderley Garcia
da Silva, Raquel Assed Bezerra
Nelson Filho, Paulo
Consolaro, Alberto
Leonardo, Mário Roberto
author_role author
author2 Araujo, Lisa Danielly Curcino
Fierro, Marcela Martín del Campo
de Paula-Silva, Francisco Wanderley Garcia
da Silva, Raquel Assed Bezerra
Nelson Filho, Paulo
Consolaro, Alberto
Leonardo, Mário Roberto
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv da Silva, Léa Assed Bezerra
Araujo, Lisa Danielly Curcino
Fierro, Marcela Martín del Campo
de Paula-Silva, Francisco Wanderley Garcia
da Silva, Raquel Assed Bezerra
Nelson Filho, Paulo
Consolaro, Alberto
Leonardo, Mário Roberto
dc.subject.por.fl_str_mv Pulpotomy
Dental Enamel
Calcium hydroxide
Zinc oxide and eugenol
topic Pulpotomy
Dental Enamel
Calcium hydroxide
Zinc oxide and eugenol
description Objective: To evaluate the pulpal and periapical response of dogs’ teeth after pulpotomy and use of Enamel Matrix Derivative (EMD) as capping agent. Methods: Pulpotomy was performed in 40 teeth from 4 dogs and the remaining pulp tissue was recovered with the following materials: Groups I and IV: EMD (Emdogain®); Groups II and V: calcium hydroxide; Groups III and VI: zinc oxide and eugenol cement. After 7 days (Groups I, II, and III) and 70 days (Groups IV, V, and VI), the animals were euthanized and the teeth were removed and processed for histological analysis; were analyzed using Kruskal-Wallis test followed by Dunn test or Mann Whitney test ( =0.05). Results: 7-day period: in Group I, it was observed a mild to moderate inflammatory infiltrate and intense vascular proliferation while Group II presented a mild inflammatory infiltrate and an intact pulp tissue (p < 0.05). Group III presented a moderate to severe inflammatory infiltrate. 70-day period: Groups IV and VI showed no dentin bridge formation, the remaining pulp tissue presented necrotic areas with inflammatory cells in the periapical region and bone and cementum resorption (p > 0.05). In Group V, there was dentin bridge formation, absence of inflammation and absence of mineralized tissue resorption (p < 0.05). Conclusion: EMD as a capping material after pulpotomy did not show either satisfactory tissue response or capacity of inducing deposition of mineralized tissue in dental pulp.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://cro-rj.org.br/revcientifica/index.php/revista/article/view/98
10.29327/24816.4.2-3
url https://cro-rj.org.br/revcientifica/index.php/revista/article/view/98
identifier_str_mv 10.29327/24816.4.2-3
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://cro-rj.org.br/revcientifica/index.php/revista/article/view/98/67
dc.rights.driver.fl_str_mv Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Rio de Janeiro Dental Journal
publisher.none.fl_str_mv Rio de Janeiro Dental Journal
dc.source.none.fl_str_mv Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); Vol. 4 No. 2: May-August 2019; 12-18
Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); v. 4 n. 2: May-August 2019; 12-18
2595-4733
1518-5249
10.29327/24816.4.2
reponame:Revista Científica do CRO-RJ (Online)
instname:Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
instacron:CRO
instname_str Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
instacron_str CRO
institution CRO
reponame_str Revista Científica do CRO-RJ (Online)
collection Revista Científica do CRO-RJ (Online)
repository.name.fl_str_mv Revista Científica do CRO-RJ (Online) - Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
repository.mail.fl_str_mv revista.cientifica@cro-rj.org.br || rorefa@terra.com.br
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dc.identifier.doi.none.fl_str_mv 10.29327/24816.4.2-3