FLUORETO E INTELIGÊNCIA: AVALIAÇÃO CRÍTICA DE UM ESTUDO DE COORTE PROSPECTIVO

• Autor(a) principal: Oliveira, Branca Heloisa
• Data de Publicação: 2021
• Outros Autores: Cruz, Laís Rueda, Normando, David, Cury, Jaime Aparecido
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica do CRO-RJ (Online)
• Texto Completo: https://cro-rj.org.br/revcientifica/index.php/revista/article/view/212
• topic: Fluoridation; Intelligence; Pregnancy; Child; fluoretação; inteligência; gravidez; criança

Introduction: Water fluoridation is considered an effective and safe strategy for preventing dental caries. However, based on a cohort study conducted in Canada that evaluated the association between exposure of pregnant women to fluoride (F) and intelligence (IQ) of offspring at 3/4 years of age, alarmist publications onsocial networks have reported that F added to water reduces children’s intelligence. Objective: To evaluate the quality of the evidence regarding exposure to F and intelligence provided by this study. To describe of the study’s main characteristics followed by critical appraisal. Synthesis of data: The concentration of F in waterconsumed by pregnant women exposed to fluoridated tap water was 4.5 times higher than in water consumed by pregnant women not exposed to fluoridated tap water; mean IQ score of the children in the two groups was the same. There was a statistically significant association between maternal urinary excretion of F and lower IQ in boys. The increase of 1 mg F / l in the self-reported intake of maternal F was associated with a decrease of 3 points in the offspring’s IQ. We identified the risk of selection and information bias, as well as potential for residual confounding, which might have affected the validity of the results. Conclusion: the study does not provide robust evidence on exposure to fluoride and impairedintelligence. Its conclusion should not be extrapolated as scientific support for proposals for changes in the fluoridation of public water supply.