DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP

Detalhes bibliográficos
Autor(a) principal: Alexandria, Adilis Kalina
Data de Publicação: 2019
Outros Autores: Tannure, Patricia Nivoloni, Nassur, Camila, Castro, Gloria Fernanda Barbosa de Araújo, de Souza, Ivete Pomarico Ribeiro
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Científica do CRO-RJ (Online)
Texto Completo: https://cro-rj.org.br/revcientifica/index.php/revista/article/view/97
Resumo: Introduction: Rhabdomyosarcoma is an aggressive malignant soft tissue neoplasm of immature mesenchymal cells treated with surgery and chemoradiotherapy. The effects of chemoradiotherapy in head induce a series of sequelae on oral cavity and growth development. Objectives: Report the case of a child undergoing treatment for rhabdomyosarcoma whose effects on the dento-maxillofacial development were cared for in order to safe guard the patient’s quality of life. Case report: Describes a case of severe dento-maxillofacial defects resulting from chemoradiation therapy for embryonal rhabdomyosarcoma in a child aswell as the dental management performed. Clinically, the patient had gingivitis, severe mobility of permanent teeth, hyposalivation, mucositis and severe trismus. The radiologic exams showed interruption of root formation of all permanent teeth and over-retention of primary teeth. Cephalometric analyses revealedmandibular and maxillary hypoplasia. Results: Was made extraction of the overretained primary teeth associated with a prophylactic program and use of artificial saliva due to hyposalivation in order to improve the quality of life of the patient. After 6 years of dental and phonoaudiologic follow-up her oral opening hasincreased and chewing and swallowing difficulties have decreased, there is no gingivitis or mucositis and she has remained free of recurrent or metastatic diseases 11 years after the initial diagnosis. Conclusion: Our report emphasizes the importance of dental treatment with a program of prevention and follow-upfor patients undergoing anticancer therapies. 
id CRO-1_fa43153c4de917ee975dc6071b1e8b4a
oai_identifier_str oai:ojs3.cro-rj.org.br:article/97
network_acronym_str CRO-1
network_name_str Revista Científica do CRO-RJ (Online)
repository_id_str
spelling DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UPDENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UPRhabdomyosarcoma, Maintenance Chemotherapy, Antineoplastic ProtocolsRabdomiossarcoma, Quimioterapia de Manutenção, Protocolos AntineoplásicosIntroduction: Rhabdomyosarcoma is an aggressive malignant soft tissue neoplasm of immature mesenchymal cells treated with surgery and chemoradiotherapy. The effects of chemoradiotherapy in head induce a series of sequelae on oral cavity and growth development. Objectives: Report the case of a child undergoing treatment for rhabdomyosarcoma whose effects on the dento-maxillofacial development were cared for in order to safe guard the patient’s quality of life. Case report: Describes a case of severe dento-maxillofacial defects resulting from chemoradiation therapy for embryonal rhabdomyosarcoma in a child aswell as the dental management performed. Clinically, the patient had gingivitis, severe mobility of permanent teeth, hyposalivation, mucositis and severe trismus. The radiologic exams showed interruption of root formation of all permanent teeth and over-retention of primary teeth. Cephalometric analyses revealedmandibular and maxillary hypoplasia. Results: Was made extraction of the overretained primary teeth associated with a prophylactic program and use of artificial saliva due to hyposalivation in order to improve the quality of life of the patient. After 6 years of dental and phonoaudiologic follow-up her oral opening hasincreased and chewing and swallowing difficulties have decreased, there is no gingivitis or mucositis and she has remained free of recurrent or metastatic diseases 11 years after the initial diagnosis. Conclusion: Our report emphasizes the importance of dental treatment with a program of prevention and follow-upfor patients undergoing anticancer therapies. Introdução: O rabdomiossarcoma é uma neoplasia maligna agressiva de tecido mole de células mesenquimais imaturas tratadas com cirurgia e quimioradioterapia. Os efeitos da quimioradioterapia na cabeça induzem uma série de sequelas na cavidade oral e no desenvolvimento do crescimento. Objetivo:Relatar o caso de uma criança em tratamento de rabdomiossarcoma cujos efeitos no desenvolvimento dento-maxilofacial foram cuidados a fim de salvaguardar a qualidade de vida do paciente. Relato de caso: Descreve um caso de defeitos dento-maxilo-faciais graves resultante de quimioradioterapia pararabdomiossarcoma embrionário em uma criança, bem como o manejo realizado. Clinicamente, a paciente apresentava gengivite, severa mobilidade dos dentes permanentes, hipossalivação, mucosite e trismo severo. Os exames radiográficos mostraram interrupção da formação radicular de todos os dentes permanentes e retenção dos dentes decíduos. Análises cefalométricas revelaram hipoplasia mandibular e maxilar. Resultados: Foi realizada a extração dos dentes decíduos retidos associado a um programa profilático e uso de saliva artificial devido à hipossalivação, a fim de melhorar a qualidade de vida do paciente. Após 6 anos de acompanhamento odontológico e fonoaudiológico, sua abertura bucal aumentou e as dificuldades de mastigação e deglutição diminuíram, não há gengivite ou mucosite e ela permaneceu livre de doenças recorrentes ou metastáticas 11 anos após o diagnóstico inicial. Conclusão: Nosso relato enfatiza a importância do tratamento odontológico com um programa de prevenção e acompanhamento para pacientes submetidos a terapias antineoplásicas.Rio de Janeiro Dental Journal2019-10-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://cro-rj.org.br/revcientifica/index.php/revista/article/view/9710.29327/24816.4.2-9Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); Vol. 4 No. 2: May-August 2019; 52-55Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); v. 4 n. 2: May-August 2019; 52-552595-47331518-524910.29327/24816.4.2reponame:Revista Científica do CRO-RJ (Online)instname:Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)instacron:CROporhttps://cro-rj.org.br/revcientifica/index.php/revista/article/view/97/73Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)info:eu-repo/semantics/openAccessAlexandria, Adilis KalinaTannure, Patricia NivoloniNassur, CamilaCastro, Gloria Fernanda Barbosa de Araújode Souza, Ivete Pomarico Ribeiro2019-12-09T19:01:58Zoai:ojs3.cro-rj.org.br:article/97Revistahttps://cro-rj.org.br/revcientifica/index.php/revistahttps://cro-rj.org.br/revcientifica/index.php/revista/oairevista.cientifica@cro-rj.org.br || rorefa@terra.com.br2595-47331518-5249opendoar:2019-12-09T19:01:58Revista Científica do CRO-RJ (Online) - Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)false
dc.title.none.fl_str_mv DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
title DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
spellingShingle DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
Alexandria, Adilis Kalina
Rhabdomyosarcoma, Maintenance Chemotherapy, Antineoplastic Protocols
Rabdomiossarcoma, Quimioterapia de Manutenção, Protocolos Antineoplásicos
title_short DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
title_full DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
title_fullStr DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
title_full_unstemmed DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
title_sort DENTOMAXILLOFACIAL SEQUELAE RESULTING FROM A CHEMORADIOTHERAPY AGAINST RHABDOMYOSARCOMA: 6-YEAR FOLLOW-UP
author Alexandria, Adilis Kalina
author_facet Alexandria, Adilis Kalina
Tannure, Patricia Nivoloni
Nassur, Camila
Castro, Gloria Fernanda Barbosa de Araújo
de Souza, Ivete Pomarico Ribeiro
author_role author
author2 Tannure, Patricia Nivoloni
Nassur, Camila
Castro, Gloria Fernanda Barbosa de Araújo
de Souza, Ivete Pomarico Ribeiro
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Alexandria, Adilis Kalina
Tannure, Patricia Nivoloni
Nassur, Camila
Castro, Gloria Fernanda Barbosa de Araújo
de Souza, Ivete Pomarico Ribeiro
dc.subject.por.fl_str_mv Rhabdomyosarcoma, Maintenance Chemotherapy, Antineoplastic Protocols
Rabdomiossarcoma, Quimioterapia de Manutenção, Protocolos Antineoplásicos
topic Rhabdomyosarcoma, Maintenance Chemotherapy, Antineoplastic Protocols
Rabdomiossarcoma, Quimioterapia de Manutenção, Protocolos Antineoplásicos
description Introduction: Rhabdomyosarcoma is an aggressive malignant soft tissue neoplasm of immature mesenchymal cells treated with surgery and chemoradiotherapy. The effects of chemoradiotherapy in head induce a series of sequelae on oral cavity and growth development. Objectives: Report the case of a child undergoing treatment for rhabdomyosarcoma whose effects on the dento-maxillofacial development were cared for in order to safe guard the patient’s quality of life. Case report: Describes a case of severe dento-maxillofacial defects resulting from chemoradiation therapy for embryonal rhabdomyosarcoma in a child aswell as the dental management performed. Clinically, the patient had gingivitis, severe mobility of permanent teeth, hyposalivation, mucositis and severe trismus. The radiologic exams showed interruption of root formation of all permanent teeth and over-retention of primary teeth. Cephalometric analyses revealedmandibular and maxillary hypoplasia. Results: Was made extraction of the overretained primary teeth associated with a prophylactic program and use of artificial saliva due to hyposalivation in order to improve the quality of life of the patient. After 6 years of dental and phonoaudiologic follow-up her oral opening hasincreased and chewing and swallowing difficulties have decreased, there is no gingivitis or mucositis and she has remained free of recurrent or metastatic diseases 11 years after the initial diagnosis. Conclusion: Our report emphasizes the importance of dental treatment with a program of prevention and follow-upfor patients undergoing anticancer therapies. 
publishDate 2019
dc.date.none.fl_str_mv 2019-10-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://cro-rj.org.br/revcientifica/index.php/revista/article/view/97
10.29327/24816.4.2-9
url https://cro-rj.org.br/revcientifica/index.php/revista/article/view/97
identifier_str_mv 10.29327/24816.4.2-9
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://cro-rj.org.br/revcientifica/index.php/revista/article/view/97/73
dc.rights.driver.fl_str_mv Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2019 Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Rio de Janeiro Dental Journal
publisher.none.fl_str_mv Rio de Janeiro Dental Journal
dc.source.none.fl_str_mv Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); Vol. 4 No. 2: May-August 2019; 52-55
Revista Científica do CRO-RJ (Rio de Janeiro Dental Journal); v. 4 n. 2: May-August 2019; 52-55
2595-4733
1518-5249
10.29327/24816.4.2
reponame:Revista Científica do CRO-RJ (Online)
instname:Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
instacron:CRO
instname_str Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
instacron_str CRO
institution CRO
reponame_str Revista Científica do CRO-RJ (Online)
collection Revista Científica do CRO-RJ (Online)
repository.name.fl_str_mv Revista Científica do CRO-RJ (Online) - Conselho Regional de Odontologia do Rio de Janeiro (CRO-RJ)
repository.mail.fl_str_mv revista.cientifica@cro-rj.org.br || rorefa@terra.com.br
_version_ 1797042306219507712