Towards an ideal antiretroviral regimen for the global HIV epidemic
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25733 |
Resumo: | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil. |
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Grinsztejn, BeatrizCoelho, Lara E.Luz, Paula M.Veloso, Valdiléa G.2018-04-10T16:21:37Z2018-04-10T16:21:37Z2017GRINSZTEJN, Beatriz, et al. Towards an ideal antiretroviral regimen for the global HIV epidemic. Journal of Virus Eradication, v. 3, p. 111–116, 2017.2055-6640https://www.arca.fiocruz.br/handle/icict/25733engTowards an ideal antiretroviral regimen for the global HIV epidemicinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.Currently, immediate initiation of antiretroviral therapy (ART) is recommended for all individuals with HIV infection. However, among the 37 million people estimated to be living with HIV/AIDS, only 17 million are actively on treatment. Optimal use of ART among HIV-infected and at-risk individuals reduces morbidity, mortality, transmission and acquisition of HIV infection. ART regimen choices are affected by factors such as economic differences between resource-rich and low- and middle-income countries (LIMC), drug availability, and considerations for use in special populations. Ideal ART regimens combine high efficacy, high tolerability, low toxicity, low pill burden, affordability and global availability. Here, we highlight five aspects to be considered when thinking of an ideal global ART regimen: (1) the co-administration with other medications especially tuberculosis treatment; (2) treatment for specific populations such as women, children, adolescents, older people and acutely infected individuals; (3) efficacy; (4) safety, tolerability and convenience; and (5) affordability and global access for all PLWH.Antiretroviral TherapyHIVAIDSTerapia Antirretroviral de Alta AtividadeHIVSíndrome de Imunodeficiência Adquiridainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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| dc.title.pt_BR.fl_str_mv |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| title |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| spellingShingle |
Towards an ideal antiretroviral regimen for the global HIV epidemic Grinsztejn, Beatriz Antiretroviral Therapy HIV AIDS Terapia Antirretroviral de Alta Atividade HIV Síndrome de Imunodeficiência Adquirida |
| title_short |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| title_full |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| title_fullStr |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| title_full_unstemmed |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| title_sort |
Towards an ideal antiretroviral regimen for the global HIV epidemic |
| author |
Grinsztejn, Beatriz |
| author_facet |
Grinsztejn, Beatriz Coelho, Lara E. Luz, Paula M. Veloso, Valdiléa G. |
| author_role |
author |
| author2 |
Coelho, Lara E. Luz, Paula M. Veloso, Valdiléa G. |
| author2_role |
author author author |
| dc.contributor.author.fl_str_mv |
Grinsztejn, Beatriz Coelho, Lara E. Luz, Paula M. Veloso, Valdiléa G. |
| dc.subject.en.pt_BR.fl_str_mv |
Antiretroviral Therapy HIV AIDS |
| topic |
Antiretroviral Therapy HIV AIDS Terapia Antirretroviral de Alta Atividade HIV Síndrome de Imunodeficiência Adquirida |
| dc.subject.decs.pt_BR.fl_str_mv |
Terapia Antirretroviral de Alta Atividade HIV Síndrome de Imunodeficiência Adquirida |
| description |
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil. |
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2017 |
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2017 |
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2018-04-10T16:21:37Z |
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2018-04-10T16:21:37Z |
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info:eu-repo/semantics/article |
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GRINSZTEJN, Beatriz, et al. Towards an ideal antiretroviral regimen for the global HIV epidemic. Journal of Virus Eradication, v. 3, p. 111–116, 2017. |
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https://www.arca.fiocruz.br/handle/icict/25733 |
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2055-6640 |
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GRINSZTEJN, Beatriz, et al. Towards an ideal antiretroviral regimen for the global HIV epidemic. Journal of Virus Eradication, v. 3, p. 111–116, 2017. 2055-6640 |
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