Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection

Bibliographic Details
Main Author: Mota, Ester Maria
Publication Date: 2005
Other Authors: Lenzi, Henrique Leonel
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/3721
http://www.scielo.br/pdf/mioc/v100n4/v100n4a12.pdf
Summary: Acknowledgments to Dr Marcelo Pelajo Machado for his criticism towards the manuscript and for his excellent participation in the theoretical discussion on the subject. To LF Caputo for her technical assistance.
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spelling Mota, Ester MariaLenzi, Henrique Leonel2011-12-15T23:36:56Z2011-12-15T23:36:56Z2005MOTA, Ester Maria; LENZI, Henrique Leonel. Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 4, p. 407-420, 2005.0074-0276https://www.arca.fiocruz.br/handle/icict/3721http://www.scielo.br/pdf/mioc/v100n4/v100n4a12.pdfAcknowledgments to Dr Marcelo Pelajo Machado for his criticism towards the manuscript and for his excellent participation in the theoretical discussion on the subject. To LF Caputo for her technical assistance.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, BrasilAngiostrongylus costaricensis lives in the cecal and mesenteric arteries of its vertebrate hosts, and causes an inflammatory disease in humans. To investigate unknown aspects of the abdominal angiostrogyliasis pathogenesis, infected Sigmodon hispidus were sequentially studied in different times of infection. The study revealed that L3 goes alternatively through two migratory courses during its development into an adult worm: lymphatic/venous-arterial and venous portal pathways. The former is considered the principal one, because it is used by most of the larvae. Like other metastrongylides, A. costaricensis passes over the pulmonary circulation to migrate from the lymphatic system to the arterial circulation, where they circulate during some days before reaching their definitive habitat. The oviposition by mature females began on 15th day. Eggs and L1 were detected mainly in the intestine and stomach, surrounded by inflammatory reaction constituted by macrophages, monocytes, and eosinophils. They were also spread to the lungs, mesenteric lymph nodes, pancreas, spleen, and kidneys. The larvae (L1) exhibited the centripetal capacity to invade the lymphatic and venous vessels of the intestine and mesentery. Adult worms that developed in the venous intrahepatic pathway migrated downstream to reach the mesenteric veins and laid eggs that embolized in the portal hepatic vessels.engFundação Oswaldo Cruz. 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dc.title.pt_BR.fl_str_mv Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
title Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
spellingShingle Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
Mota, Ester Maria
Angiostrongylus costaricensis
Life Cycle
Sigmodon hispidus
Liver
Angiostrongylus
Fases do Ciclo de Vida
Fígado
title_short Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
title_full Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
title_fullStr Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
title_full_unstemmed Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
title_sort Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection
author Mota, Ester Maria
author_facet Mota, Ester Maria
Lenzi, Henrique Leonel
author_role author
author2 Lenzi, Henrique Leonel
author2_role author
dc.contributor.author.fl_str_mv Mota, Ester Maria
Lenzi, Henrique Leonel
dc.subject.en.pt_BR.fl_str_mv Angiostrongylus costaricensis
Life Cycle
Sigmodon hispidus
Liver
topic Angiostrongylus costaricensis
Life Cycle
Sigmodon hispidus
Liver
Angiostrongylus
Fases do Ciclo de Vida
Fígado
dc.subject.decs.pt_BR.fl_str_mv Angiostrongylus
Fases do Ciclo de Vida
Fígado
description Acknowledgments to Dr Marcelo Pelajo Machado for his criticism towards the manuscript and for his excellent participation in the theoretical discussion on the subject. To LF Caputo for her technical assistance.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2011-12-15T23:36:56Z
dc.date.available.fl_str_mv 2011-12-15T23:36:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MOTA, Ester Maria; LENZI, Henrique Leonel. Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 4, p. 407-420, 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/3721
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv http://www.scielo.br/pdf/mioc/v100n4/v100n4a12.pdf
identifier_str_mv MOTA, Ester Maria; LENZI, Henrique Leonel. Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 4, p. 407-420, 2005.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/3721
http://www.scielo.br/pdf/mioc/v100n4/v100n4a12.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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