Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session

Detalhes bibliográficos
Autor(a) principal: Lopes, Edmundo Pessoa
Data de Publicação: 2009
Outros Autores: Sette, Luis Henrique B. C., Sette, Jorge Bezerra C., Luna, Carlos F., Andrade, Amaro M., Moraes, Maviael, Sette, Paulo C. A., Menezes, Roberto, Cavalcanti, Rui L., Conceição, Sergio C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27699
Resumo: Universidade Federal de Pernambuco. Department of Medicine. Recife, PE, Brazil.
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spelling Lopes, Edmundo PessoaSette, Luis Henrique B. C.Sette, Jorge Bezerra C.Luna, Carlos F.Andrade, Amaro M.Moraes, MaviaelSette, Paulo C. A.Menezes, RobertoCavalcanti, Rui L.Conceição, Sergio C.2018-07-30T13:09:04Z2018-07-30T13:09:04Z2009LOPES, E. P. et al. Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session. Clinics, v. 64, n. 10, p. 941-945, 2009.1980-5322https://www.arca.fiocruz.br/handle/icict/2769910.1590/S1807-59322009001000002engAlanina aminotransferaseInsuficiência renal crônicaHemodiáliseHepatite CAlanine aminotransferaseChronic renal failureHemodialysisHepatitis CAdolescenteAdultoEnvelhecidoIdoso, 80 anos ou maisAlanina Transaminase / sangueFêmeaHematócritoHumanosInsuficiência Renal Crônica / SangueInsuficiência Renal Crônica / terapiaMasculinoMeia idadeCurva ROCHemodiáliseFatores de TempoPerda de peso / fisiologiaAdulto jovemSerum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis sessioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Pernambuco. Department of Medicine. Recife, PE, Brazil.Dialysis Unit. NEFRO CLÍNICA. Recife, PE, Brazil.Universidade Federal de Pernambuco. Department of Medicine. Recife, PE, Brazil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Universidade Federal de Pernambuco. Department of Medicine. Recife, PE, Brazil.Dialysis Unit. NEFRO CLÍNICA. Recife, PE, Brazil.Dialysis Unit. NEFRO CLÍNICA. Recife, PE, Brazil.Dialysis Unit. NEFRO CLÍNICA. Recife, PE, Brazil.Dialysis Unit. NEFRO CLÍNICA. Recife, PE, Brazil.PURPOSE: To evaluate alanine aminotransferase levels before and after a hemodialysis session and to correlate these values with the hematocrit rate and weight loss during hemodialysis. PATIENTS AND METHODS: The serum alanine aminotransferase levels, hematocrit rate and body weight were measured and correlated before and after a single hemodialysis session for 146 patients with chronic renal failure. An receiver operating characteristic (ROC) curve for the serum alanine aminotransferase levels collected before and after hemodialysis was plotted to identify hepatitis C virus-infected patients. RESULTS: The mean weight loss of the 146 patients during hemodialysis was 5.3% (p < 0.001). The mean alanine aminotransferase levels before and after hemodialysis were 18.8 and 23.9 IU/, respectively, denoting a significant 28.1% increase. An equally significant increase of 16.4% in the hematocrit rate also occurred after hemodialysis. The weight loss was inversely correlated with the rise in both the alanine aminotransferase level (r = 0.3; p < 0.001) and hematocrit rate (r = 0.5; p < 0.001). A direct correlation was found between the rise in alanine aminotransferase levels and the hematocrit during the hemodialysis session (r = 0.4; p < 0.001). Based on the ROC curve, the upper limit of the normal alanine aminotransferase level should be reduced by 40% relative to the upper limit of normal if the blood samples are collected before the hemodialysis session or by 60% if blood samples are collected after the session. CONCLUSION: In the present study, significant elevations in the serum alanine aminotransferase levels and hematocrit rates occurred in parallel to a reduction in body weight after the hemodialysis session. These findings suggest that one of the factors for low alanine aminotransferase levels prior to hemodialysis could be hemodilution in patients with chronic renal failure.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/27699/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALSERUM ALANINE AMINOTRANSFERASE.pdfSERUM ALANINE AMINOTRANSFERASE.pdfapplication/pdf145894https://www.arca.fiocruz.br/bitstream/icict/27699/2/SERUM%20ALANINE%20AMINOTRANSFERASE.pdf8d0308f750ca58c5b3da8c4ff05b9653MD52TEXTSERUM ALANINE AMINOTRANSFERASE.pdf.txtSERUM ALANINE AMINOTRANSFERASE.pdf.txtExtracted texttext/plain22453https://www.arca.fiocruz.br/bitstream/icict/27699/3/SERUM%20ALANINE%20AMINOTRANSFERASE.pdf.txt53994be275891e13f8564856b14ef6b7MD53icict/276992018-08-15 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dc.title.pt_BR.fl_str_mv Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
title Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
spellingShingle Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
Lopes, Edmundo Pessoa
Alanina aminotransferase
Insuficiência renal crônica
Hemodiálise
Hepatite C
Alanine aminotransferase
Chronic renal failure
Hemodialysis
Hepatitis C
Adolescente
Adulto
Envelhecido
Idoso, 80 anos ou mais
Alanina Transaminase / sangue
Fêmea
Hematócrito
Humanos
Insuficiência Renal Crônica / Sangue
Insuficiência Renal Crônica / terapia
Masculino
Meia idade
Curva ROC
Hemodiálise
Fatores de Tempo
Perda de peso / fisiologia
Adulto jovem
title_short Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
title_full Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
title_fullStr Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
title_full_unstemmed Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
title_sort Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session
author Lopes, Edmundo Pessoa
author_facet Lopes, Edmundo Pessoa
Sette, Luis Henrique B. C.
Sette, Jorge Bezerra C.
Luna, Carlos F.
Andrade, Amaro M.
Moraes, Maviael
Sette, Paulo C. A.
Menezes, Roberto
Cavalcanti, Rui L.
Conceição, Sergio C.
author_role author
author2 Sette, Luis Henrique B. C.
Sette, Jorge Bezerra C.
Luna, Carlos F.
Andrade, Amaro M.
Moraes, Maviael
Sette, Paulo C. A.
Menezes, Roberto
Cavalcanti, Rui L.
Conceição, Sergio C.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Edmundo Pessoa
Sette, Luis Henrique B. C.
Sette, Jorge Bezerra C.
Luna, Carlos F.
Andrade, Amaro M.
Moraes, Maviael
Sette, Paulo C. A.
Menezes, Roberto
Cavalcanti, Rui L.
Conceição, Sergio C.
dc.subject.other.pt_BR.fl_str_mv Alanina aminotransferase
Insuficiência renal crônica
Hemodiálise
Hepatite C
topic Alanina aminotransferase
Insuficiência renal crônica
Hemodiálise
Hepatite C
Alanine aminotransferase
Chronic renal failure
Hemodialysis
Hepatitis C
Adolescente
Adulto
Envelhecido
Idoso, 80 anos ou mais
Alanina Transaminase / sangue
Fêmea
Hematócrito
Humanos
Insuficiência Renal Crônica / Sangue
Insuficiência Renal Crônica / terapia
Masculino
Meia idade
Curva ROC
Hemodiálise
Fatores de Tempo
Perda de peso / fisiologia
Adulto jovem
dc.subject.en.pt_BR.fl_str_mv Alanine aminotransferase
Chronic renal failure
Hemodialysis
Hepatitis C
dc.subject.decs.pt_BR.fl_str_mv Adolescente
Adulto
Envelhecido
Idoso, 80 anos ou mais
Alanina Transaminase / sangue
Fêmea
Hematócrito
Humanos
Insuficiência Renal Crônica / Sangue
Insuficiência Renal Crônica / terapia
Masculino
Meia idade
Curva ROC
Hemodiálise
Fatores de Tempo
Perda de peso / fisiologia
Adulto jovem
description Universidade Federal de Pernambuco. Department of Medicine. Recife, PE, Brazil.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2018-07-30T13:09:04Z
dc.date.available.fl_str_mv 2018-07-30T13:09:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LOPES, E. P. et al. Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session. Clinics, v. 64, n. 10, p. 941-945, 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27699
dc.identifier.issn.pt_BR.fl_str_mv 1980-5322
dc.identifier.doi.none.fl_str_mv 10.1590/S1807-59322009001000002
identifier_str_mv LOPES, E. P. et al. Serum alanine aminotransferase levels, hematocrit rate and body weight correlations before and after hemodialysis session. Clinics, v. 64, n. 10, p. 941-945, 2009.
1980-5322
10.1590/S1807-59322009001000002
url https://www.arca.fiocruz.br/handle/icict/27699
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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