Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil

Detalhes bibliográficos
Autor(a) principal: Freitas, Nara Rubia de
Data de Publicação: 2016
Outros Autores: Santana, Edna Braz Rocha de, Silva, Ágabo Macedo da Costa e, Silva, Sueli Meira da, Teles, Sheila Araújo, Gardinalli, Noemi Rovaris, Pinto, Marcelo Alves, Martins, Regina Maria Bringel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/17931
Resumo: Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil
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spelling Freitas, Nara Rubia deSantana, Edna Braz Rocha deSilva, Ágabo Macedo da Costa eSilva, Sueli Meira daTeles, Sheila AraújoGardinalli, Noemi RovarisPinto, Marcelo AlvesMartins, Regina Maria Bringel2017-03-05T14:08:52Z2017-03-05T14:08:52Z2016FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016.1678-8080https://www.arca.fiocruz.br/handle/icict/1793110.1590/0074-02760160256engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Vírus da hepatite EBrasil CentralEpidemiologiahepatite não-A, não-B-CHepatitis E virusHEVepidemiologynon-A, non-B, non-C hepatitisCentral BrazilHepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilHepatitis E virus (HEV) infection has a worldwide distribution and represents an important cause of acute hepatitis. This study aims to investigate the occurrence of HEV infection and factors associated with this infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. From April 2012 to October 2014, a crosssectional study was conducted among 379 patients with acute non-A, non-B, non-C hepatitis in the City of Goiania, Central Brazil. Serum samples of all patients were tested for serological markers of HEV infection (anti-HEV IgM and IgG) by ELISA. Positive samples were confirmed using immunoblot test. Anti-HEV IgM and IgG positive samples were tested for HEV RNA. Of the 379 serum samples, one (0.3%) and 20 (5.3%) were positive for anti-HEV IgM and IgG, respectively. HEV RNA was not found in any sample positive for IgM and/or IgG anti-HEV. After multivariate analysis, low education level was independently associated with HEV seropositivity (p = 0.005), as well as living in rural area, with a borderline p-value (p = 0.056). In conclusion, HEV may be responsible for sporadic self-limited cases of acute hepatitis in Central Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/17931/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALnoemi_gardinalli_etal_IOC_2016.pdfnoemi_gardinalli_etal_IOC_2016.pdfapplication/pdf261895https://www.arca.fiocruz.br/bitstream/icict/17931/2/noemi_gardinalli_etal_IOC_2016.pdfc450cf6e32a7e4a8df9aa4e018249cc2MD52TEXTnoemi_gardinalli_etal_IOC_2016.pdf.txtnoemi_gardinalli_etal_IOC_2016.pdf.txtExtracted texttext/plain26294https://www.arca.fiocruz.br/bitstream/icict/17931/3/noemi_gardinalli_etal_IOC_2016.pdf.txtb6131c8d33103e404a9a56c1990fecdfMD53icict/179312018-08-15 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dc.title.pt_BR.fl_str_mv Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
title Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
spellingShingle Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
Freitas, Nara Rubia de
Vírus da hepatite E
Brasil Central
Epidemiologia
hepatite não-A, não-B-C
Hepatitis E virus
HEV
epidemiology
non-A, non-B, non-C hepatitis
Central Brazil
title_short Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
title_full Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
title_fullStr Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
title_full_unstemmed Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
title_sort Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
author Freitas, Nara Rubia de
author_facet Freitas, Nara Rubia de
Santana, Edna Braz Rocha de
Silva, Ágabo Macedo da Costa e
Silva, Sueli Meira da
Teles, Sheila Araújo
Gardinalli, Noemi Rovaris
Pinto, Marcelo Alves
Martins, Regina Maria Bringel
author_role author
author2 Santana, Edna Braz Rocha de
Silva, Ágabo Macedo da Costa e
Silva, Sueli Meira da
Teles, Sheila Araújo
Gardinalli, Noemi Rovaris
Pinto, Marcelo Alves
Martins, Regina Maria Bringel
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Nara Rubia de
Santana, Edna Braz Rocha de
Silva, Ágabo Macedo da Costa e
Silva, Sueli Meira da
Teles, Sheila Araújo
Gardinalli, Noemi Rovaris
Pinto, Marcelo Alves
Martins, Regina Maria Bringel
dc.subject.other.pt_BR.fl_str_mv Vírus da hepatite E
Brasil Central
Epidemiologia
hepatite não-A, não-B-C
topic Vírus da hepatite E
Brasil Central
Epidemiologia
hepatite não-A, não-B-C
Hepatitis E virus
HEV
epidemiology
non-A, non-B, non-C hepatitis
Central Brazil
dc.subject.en.pt_BR.fl_str_mv Hepatitis E virus
HEV
epidemiology
non-A, non-B, non-C hepatitis
Central Brazil
description Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-03-05T14:08:52Z
dc.date.available.fl_str_mv 2017-03-05T14:08:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/17931
dc.identifier.issn.pt_BR.fl_str_mv 1678-8080
dc.identifier.doi.none.fl_str_mv 10.1590/0074-02760160256
identifier_str_mv FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016.
1678-8080
10.1590/0074-02760160256
url https://www.arca.fiocruz.br/handle/icict/17931
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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