Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/17931 |
Resumo: | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil |
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Freitas, Nara Rubia deSantana, Edna Braz Rocha deSilva, Ágabo Macedo da Costa eSilva, Sueli Meira daTeles, Sheila AraújoGardinalli, Noemi RovarisPinto, Marcelo AlvesMartins, Regina Maria Bringel2017-03-05T14:08:52Z2017-03-05T14:08:52Z2016FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016.1678-8080https://www.arca.fiocruz.br/handle/icict/1793110.1590/0074-02760160256engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Vírus da hepatite EBrasil CentralEpidemiologiahepatite não-A, não-B-CHepatitis E virusHEVepidemiologynon-A, non-B, non-C hepatitisCentral BrazilHepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilUniversidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, BrasilHepatitis E virus (HEV) infection has a worldwide distribution and represents an important cause of acute hepatitis. This study aims to investigate the occurrence of HEV infection and factors associated with this infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. From April 2012 to October 2014, a crosssectional study was conducted among 379 patients with acute non-A, non-B, non-C hepatitis in the City of Goiania, Central Brazil. Serum samples of all patients were tested for serological markers of HEV infection (anti-HEV IgM and IgG) by ELISA. Positive samples were confirmed using immunoblot test. Anti-HEV IgM and IgG positive samples were tested for HEV RNA. Of the 379 serum samples, one (0.3%) and 20 (5.3%) were positive for anti-HEV IgM and IgG, respectively. HEV RNA was not found in any sample positive for IgM and/or IgG anti-HEV. After multivariate analysis, low education level was independently associated with HEV seropositivity (p = 0.005), as well as living in rural area, with a borderline p-value (p = 0.056). In conclusion, HEV may be responsible for sporadic self-limited cases of acute hepatitis in Central Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/17931/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALnoemi_gardinalli_etal_IOC_2016.pdfnoemi_gardinalli_etal_IOC_2016.pdfapplication/pdf261895https://www.arca.fiocruz.br/bitstream/icict/17931/2/noemi_gardinalli_etal_IOC_2016.pdfc450cf6e32a7e4a8df9aa4e018249cc2MD52TEXTnoemi_gardinalli_etal_IOC_2016.pdf.txtnoemi_gardinalli_etal_IOC_2016.pdf.txtExtracted texttext/plain26294https://www.arca.fiocruz.br/bitstream/icict/17931/3/noemi_gardinalli_etal_IOC_2016.pdf.txtb6131c8d33103e404a9a56c1990fecdfMD53icict/179312018-08-15 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dc.title.pt_BR.fl_str_mv |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
title |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
spellingShingle |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil Freitas, Nara Rubia de Vírus da hepatite E Brasil Central Epidemiologia hepatite não-A, não-B-C Hepatitis E virus HEV epidemiology non-A, non-B, non-C hepatitis Central Brazil |
title_short |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
title_full |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
title_fullStr |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
title_full_unstemmed |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
title_sort |
Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil |
author |
Freitas, Nara Rubia de |
author_facet |
Freitas, Nara Rubia de Santana, Edna Braz Rocha de Silva, Ágabo Macedo da Costa e Silva, Sueli Meira da Teles, Sheila Araújo Gardinalli, Noemi Rovaris Pinto, Marcelo Alves Martins, Regina Maria Bringel |
author_role |
author |
author2 |
Santana, Edna Braz Rocha de Silva, Ágabo Macedo da Costa e Silva, Sueli Meira da Teles, Sheila Araújo Gardinalli, Noemi Rovaris Pinto, Marcelo Alves Martins, Regina Maria Bringel |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Freitas, Nara Rubia de Santana, Edna Braz Rocha de Silva, Ágabo Macedo da Costa e Silva, Sueli Meira da Teles, Sheila Araújo Gardinalli, Noemi Rovaris Pinto, Marcelo Alves Martins, Regina Maria Bringel |
dc.subject.other.pt_BR.fl_str_mv |
Vírus da hepatite E Brasil Central Epidemiologia hepatite não-A, não-B-C |
topic |
Vírus da hepatite E Brasil Central Epidemiologia hepatite não-A, não-B-C Hepatitis E virus HEV epidemiology non-A, non-B, non-C hepatitis Central Brazil |
dc.subject.en.pt_BR.fl_str_mv |
Hepatitis E virus HEV epidemiology non-A, non-B, non-C hepatitis Central Brazil |
description |
Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2017-03-05T14:08:52Z |
dc.date.available.fl_str_mv |
2017-03-05T14:08:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/17931 |
dc.identifier.issn.pt_BR.fl_str_mv |
1678-8080 |
dc.identifier.doi.none.fl_str_mv |
10.1590/0074-02760160256 |
identifier_str_mv |
FREITAS, Naa Rubia de; et al. Hepatitis E virus infection in patients with acute non-A, non-B, non-C hepatitis in Central Brazil. Mem Inst Oswaldo Cruz, v.111, n.11, 5p, 2016. 1678-8080 10.1590/0074-02760160256 |
url |
https://www.arca.fiocruz.br/handle/icict/17931 |
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eng |
language |
eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
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Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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