Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Brandão, Luciana Gomes Pedro
Data de Publicação: 2023
Outros Autores: Tuyama, Mari, Carvalho, Flavio de, Santos, Ananza Taina da Silva, Lemos, Alberto dos Santos de, Costa, Marcellus Dias da, Mesquita, Emersom Cicilini, Cerbino-Neto, José, Varela, Margareth Catoia, Brasil, Pedro Emmanuel Alvarenga Americano do, Rondon, Angelica Varela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60578
Resumo: Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.
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spelling Brandão, Luciana Gomes PedroTuyama, MariCarvalho, Flavio deSantos, Ananza Taina da SilvaLemos, Alberto dos Santos deCosta, Marcellus Dias daMesquita, Emersom CiciliniCerbino-Neto, JoséVarela, Margareth CatoiaBrasil, Pedro Emmanuel Alvarenga Americano doRondon, Angelica Varela2023-09-28T00:44:07Z2023-09-28T00:44:07Z2023BRANDÃO, Luciana Gomes Pedro et al. Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil. Journal of Allergy and Clinical Immunology Global, v. 2, n. 3, p. 1-5, Aug. 2023.2772-8293https://www.arca.fiocruz.br/handle/icict/6057810.1016/j.jacig.2023.100101engElsevierOverdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleOswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil.Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure. However, using only clinical history to diagnose previous allergic reactions may lead to overdiagnosis of vaccine allergy and even to the use of medical exemptions as a subterfuge to mandatory vaccination. Methods: We conducted a retrospective study to describe the outcomes of patients with a history of vaccine or vaccine component allergy who were evaluated at our unit from 2011 to 2017. Data on allergy history, skin test results, vaccines prescribed, and adverse events were retrieved from the medical records at the Centro de Referencia para Imunobiologicos Especiais (Reference Center of Special immunobiologicals)–Fiocruz, in Rio de Janeiro, Brazil. Results: Of 34 adults with history of allergy to vaccine or vaccine components, 32 (94.1%) were successfully vaccinated without serious adverse events after our evaluation. In 12 patients (35%), the time elapsed between the allergy symptoms and evaluation in the Centro de Referencia para Imunobiologicos Especiais–Fiocruz was more than 10 years. Conclusion: Specialized care and use of skin tests allowed safe vaccination of the majority of patients. An objective, systematic evaluation of a history of vaccine allergy can prevent its improper use to avoid mandatory vaccination and reduce missed opportunities for immunization.AdultsAllergyVaccineImmunizationHypersensitivitySkin allergic testPrick testAdverse eventinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60578/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Luciana_Brandão_etal_INI_2023.pdfve_Luciana_Brandão_etal_INI_2023.pdfapplication/pdf548361https://www.arca.fiocruz.br/bitstream/icict/60578/2/ve_Luciana_Brand%c3%a3o_etal_INI_2023.pdfa10ae834b52cc9e8056afdc7d62deebcMD52icict/605782023-10-02 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dc.title.en_US.fl_str_mv Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
title Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
spellingShingle Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
Brandão, Luciana Gomes Pedro
Adults
Allergy
Vaccine
Immunization
Hypersensitivity
Skin allergic test
Prick test
Adverse event
title_short Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
title_full Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
title_fullStr Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
title_full_unstemmed Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
title_sort Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil
author Brandão, Luciana Gomes Pedro
author_facet Brandão, Luciana Gomes Pedro
Tuyama, Mari
Carvalho, Flavio de
Santos, Ananza Taina da Silva
Lemos, Alberto dos Santos de
Costa, Marcellus Dias da
Mesquita, Emersom Cicilini
Cerbino-Neto, José
Varela, Margareth Catoia
Brasil, Pedro Emmanuel Alvarenga Americano do
Rondon, Angelica Varela
author_role author
author2 Tuyama, Mari
Carvalho, Flavio de
Santos, Ananza Taina da Silva
Lemos, Alberto dos Santos de
Costa, Marcellus Dias da
Mesquita, Emersom Cicilini
Cerbino-Neto, José
Varela, Margareth Catoia
Brasil, Pedro Emmanuel Alvarenga Americano do
Rondon, Angelica Varela
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Brandão, Luciana Gomes Pedro
Tuyama, Mari
Carvalho, Flavio de
Santos, Ananza Taina da Silva
Lemos, Alberto dos Santos de
Costa, Marcellus Dias da
Mesquita, Emersom Cicilini
Cerbino-Neto, José
Varela, Margareth Catoia
Brasil, Pedro Emmanuel Alvarenga Americano do
Rondon, Angelica Varela
dc.subject.en.en_US.fl_str_mv Adults
Allergy
Vaccine
Immunization
Hypersensitivity
Skin allergic test
Prick test
Adverse event
topic Adults
Allergy
Vaccine
Immunization
Hypersensitivity
Skin allergic test
Prick test
Adverse event
description Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Reference Center for Special Immunobiologicals. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Disease Evandro Chagas. Health Surveillance and Immunization Research Unit. Rio de Janeiro, RJ, Brazil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-09-28T00:44:07Z
dc.date.available.fl_str_mv 2023-09-28T00:44:07Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BRANDÃO, Luciana Gomes Pedro et al. Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil. Journal of Allergy and Clinical Immunology Global, v. 2, n. 3, p. 1-5, Aug. 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60578
dc.identifier.issn.en_US.fl_str_mv 2772-8293
dc.identifier.doi.none.fl_str_mv 10.1016/j.jacig.2023.100101
identifier_str_mv BRANDÃO, Luciana Gomes Pedro et al. Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil. Journal of Allergy and Clinical Immunology Global, v. 2, n. 3, p. 1-5, Aug. 2023.
2772-8293
10.1016/j.jacig.2023.100101
url https://www.arca.fiocruz.br/handle/icict/60578
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60578/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60578/2/ve_Luciana_Brand%c3%a3o_etal_INI_2023.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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