Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine

Detalhes bibliográficos
Autor(a) principal: Badaró, Roberto
Data de Publicação: 2023
Outros Autores: Novaes, Gustavo, Andrade, Ana Cristina, Araujo Neto, Cesar Augusto de, Machado, Bruna Aparecida, Barbosa, Josiane Dantas Viana, Soares, Milena Botelho Pereira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/58957
Resumo: Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde, Centro Universitário. Conselho Nacional do Brasil (CNPq).
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spelling Badaró, RobertoNovaes, GustavoAndrade, Ana CristinaAraujo Neto, Cesar Augusto deMachado, Bruna AparecidaBarbosa, Josiane Dantas VianaSoares, Milena Botelho Pereira2023-06-06T18:31:13Z2023-06-06T18:31:13Z2023BADARÓ, Roberto et al. Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine. Frontiers in Medicine, v. 10, p. 1-6, 2023.2296-858Xhttps://www.arca.fiocruz.br/handle/icict/5895710.3389/fmed.2023.1071239Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde, Centro Universitário. Conselho Nacional do Brasil (CNPq).Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil / Clínica Especializada Allmed. Salvador, BA, Brasil.Hospital UNIMED. Feira de Santana, BA, Brasil.Clínica Especializada Allmed. Salvador, BA, Brasil.Diagnóstico por Imagem, Salvador, BA, Brasil.Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil.Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil.Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.A 23-year-old man started with chest pain 8 h after his first Pfizer-BioNTech COVID 19 vaccination. ECG evaluation showed sinus tachycardia with ST-segment elevation in D1, AVL, V5, and V6, the findings compatible with acute subepicardial myocardial damage. However, cardiac MRI documented myocardial fibrosis, with cardiac late enhancement non-ischemic pattern with diffuse edema. He had no other symptoms to suggest another etiology than the vaccination. The patient was hospitalized and received corticosteroid (prednisolone) daily. Then, 2 weeks after hospitalization, all laboratory parameters and ECG were normal and the patient was discharged from the hospital. The patient had a history of Wolf-Parkinson White that was corrected with ablation when he was 11 years old. This report calls attention to myocardial adverse reaction risk for mRNA COVID-19 vaccines for people with a previous cardiac disease history.engFrontiers MediaCOVID-19Vacina mRNACardiotoxicidadeDoença cardíacaEvento adversoCOVID-19mRNA vaccineCardiotoxicityCardiac diseaseAdverse eventCOVID-19Vacina de mRNA-1273 contra 2019-nCoVCardiotoxicidadeDoenças CardiovascularesMyocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/58957/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBadaró, R. Myocardial infarction....pdfBadaró, R. Myocardial infarction....pdfapplication/pdf1110127https://www.arca.fiocruz.br/bitstream/icict/58957/2/Badar%c3%b3%2c%20R.%20Myocardial%20infarction....pdf37eb27a70d2509db924b7c933d795070MD52icict/589572023-06-06 15:31:14.782oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-06-06T18:31:14Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
title Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
spellingShingle Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
Badaró, Roberto
COVID-19
Vacina mRNA
Cardiotoxicidade
Doença cardíaca
Evento adverso
COVID-19
mRNA vaccine
Cardiotoxicity
Cardiac disease
Adverse event
COVID-19
Vacina de mRNA-1273 contra 2019-nCoV
Cardiotoxicidade
Doenças Cardiovasculares
title_short Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
title_full Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
title_fullStr Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
title_full_unstemmed Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
title_sort Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
author Badaró, Roberto
author_facet Badaró, Roberto
Novaes, Gustavo
Andrade, Ana Cristina
Araujo Neto, Cesar Augusto de
Machado, Bruna Aparecida
Barbosa, Josiane Dantas Viana
Soares, Milena Botelho Pereira
author_role author
author2 Novaes, Gustavo
Andrade, Ana Cristina
Araujo Neto, Cesar Augusto de
Machado, Bruna Aparecida
Barbosa, Josiane Dantas Viana
Soares, Milena Botelho Pereira
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Badaró, Roberto
Novaes, Gustavo
Andrade, Ana Cristina
Araujo Neto, Cesar Augusto de
Machado, Bruna Aparecida
Barbosa, Josiane Dantas Viana
Soares, Milena Botelho Pereira
dc.subject.other.en_US.fl_str_mv COVID-19
Vacina mRNA
Cardiotoxicidade
Doença cardíaca
Evento adverso
topic COVID-19
Vacina mRNA
Cardiotoxicidade
Doença cardíaca
Evento adverso
COVID-19
mRNA vaccine
Cardiotoxicity
Cardiac disease
Adverse event
COVID-19
Vacina de mRNA-1273 contra 2019-nCoV
Cardiotoxicidade
Doenças Cardiovasculares
dc.subject.en.en_US.fl_str_mv COVID-19
mRNA vaccine
Cardiotoxicity
Cardiac disease
Adverse event
dc.subject.decs.en_US.fl_str_mv COVID-19
Vacina de mRNA-1273 contra 2019-nCoV
Cardiotoxicidade
Doenças Cardiovasculares
description Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde, Centro Universitário. Conselho Nacional do Brasil (CNPq).
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-06-06T18:31:13Z
dc.date.available.fl_str_mv 2023-06-06T18:31:13Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BADARÓ, Roberto et al. Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine. Frontiers in Medicine, v. 10, p. 1-6, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/58957
dc.identifier.issn.en_US.fl_str_mv 2296-858X
dc.identifier.doi.none.fl_str_mv 10.3389/fmed.2023.1071239
identifier_str_mv BADARÓ, Roberto et al. Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine. Frontiers in Medicine, v. 10, p. 1-6, 2023.
2296-858X
10.3389/fmed.2023.1071239
url https://www.arca.fiocruz.br/handle/icict/58957
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/58957/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/58957/2/Badar%c3%b3%2c%20R.%20Myocardial%20infarction....pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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