Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice

Detalhes bibliográficos
Autor(a) principal: Borges, Monamaris Marques
Data de Publicação: 1995
Outros Autores: Vassao, Ruth, Andrade, Sonia Gumes, Pereira, Carlos Augusto, Kloetzel, Judith K
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19513
Resumo: CNPq, LIM (Hospital das Clinicas) and Fundação Butantan. C. A.
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spelling Borges, Monamaris MarquesVassao, RuthAndrade, Sonia GumesPereira, Carlos AugustoKloetzel, Judith K2017-06-26T17:06:12Z2017-06-26T17:06:12Z1995BORGES, M. M. et al. Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice. Parasitology Research, v. 81, p. 498-504, 1995.0932-0113https://www.arca.fiocruz.br/handle/icict/19513CNPq, LIM (Hospital das Clinicas) and Fundação Butantan. C. A.Instituto de Medicina Tropical de São Paulo. São Paulo, SP, BrasilInstituto Butantan. Laboratório de Imanunologia Viral. São Paulo, SP, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilInstituto Butantan. Laboratório de Imanunologia Viral. São Paulo, SP, BrasilInstituto de Medicina Tropical de São Paulo. São Paulo, SP, Brasil / Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. São Paulo, SP, BrasilSerum levels of interferon-gamma (IFN-y) were evaluated in Calomys callosus and Swiss mice during the course of infection by four strains of Trypanosoma cruzi. All strains stimulated the production of this interleukine; however, the timing of its onset and permanence varied among strains and between the two animal models. When chronically infected animals with no detectable serum IFN-y were challenged with the homologous strain, they produced quantities comparable with those obtained during the acute phase of infection. In C. callosus there was a correlation between H202 liberation by peritoneal macrophages and serum IFN-y levels, whereas no such correlation was found in mice. C. callosus had a higher capacity to heal histopathological lesions, whereas lesions in mice were progressive, The results obtained suggest that C. callosus develops welladapted immune mechanisms that may be important for its role as a reservoir of T. cruzi.engSpringer VerlagTrypanosoma cruziRodentiaAnimaisInfecçãoRatosInterferon gamaTrypanosoma cruziRodentiaAnimalsInfectionMiceInterferon gammaInterferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss miceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19513/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBorges M INF-y during the course....pdfBorges M INF-y during the 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dc.title.pt_BR.fl_str_mv Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
title Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
spellingShingle Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
Borges, Monamaris Marques
Trypanosoma cruzi
Rodentia
Animais
Infecção
Ratos
Interferon gama
Trypanosoma cruzi
Rodentia
Animals
Infection
Mice
Interferon gamma
title_short Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
title_full Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
title_fullStr Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
title_full_unstemmed Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
title_sort Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice
author Borges, Monamaris Marques
author_facet Borges, Monamaris Marques
Vassao, Ruth
Andrade, Sonia Gumes
Pereira, Carlos Augusto
Kloetzel, Judith K
author_role author
author2 Vassao, Ruth
Andrade, Sonia Gumes
Pereira, Carlos Augusto
Kloetzel, Judith K
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Borges, Monamaris Marques
Vassao, Ruth
Andrade, Sonia Gumes
Pereira, Carlos Augusto
Kloetzel, Judith K
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Rodentia
Animais
Infecção
Ratos
Interferon gama
topic Trypanosoma cruzi
Rodentia
Animais
Infecção
Ratos
Interferon gama
Trypanosoma cruzi
Rodentia
Animals
Infection
Mice
Interferon gamma
dc.subject.en.pt_BR.fl_str_mv Trypanosoma cruzi
Rodentia
Animals
Infection
Mice
Interferon gamma
description CNPq, LIM (Hospital das Clinicas) and Fundação Butantan. C. A.
publishDate 1995
dc.date.issued.fl_str_mv 1995
dc.date.accessioned.fl_str_mv 2017-06-26T17:06:12Z
dc.date.available.fl_str_mv 2017-06-26T17:06:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BORGES, M. M. et al. Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice. Parasitology Research, v. 81, p. 498-504, 1995.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19513
dc.identifier.issn.pt_BR.fl_str_mv 0932-0113
identifier_str_mv BORGES, M. M. et al. Interferon-gamma levels during the course of Trypanosoma cruzi infection of Calomys callosu$ (Rodentia-Cricetidae) and Swiss mice. Parasitology Research, v. 81, p. 498-504, 1995.
0932-0113
url https://www.arca.fiocruz.br/handle/icict/19513
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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