Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil

Detalhes bibliográficos
Autor(a) principal: Kmetiuk, Louise Bach
Data de Publicação: 2023
Outros Autores: Gonçalves, Gustavo, Couto, Anahi Chechia do, Biondo, Alexander Welker, Figueiredo, Fabiano Borges
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/57823
http://doi.org/10.3389/fpubh.2023.1125028
Resumo: Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Celular. Curitiba, PR, Brasil.
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spelling Kmetiuk, Louise BachGonçalves, GustavoCouto, Anahi Chechia doBiondo, Alexander WelkerFigueiredo, Fabiano Borges2023-04-17T13:07:23Z2023-04-17T13:07:23Z2023KMETIUK, Louise Bach et al. Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil. Front. Public Health 11:1125028, p. 1–4, 2023.2296-2565https://www.arca.fiocruz.br/handle/icict/57823http://doi.org/10.3389/fpubh.2023.1125028porFrontiers MediaSerosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Celular. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Celular. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Medicina Veterinária. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Medicina Veterinária. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Celular. Curitiba, PR, Brasil.Although Chagas disease, caused by Trypanosoma cruzi, has been associated with social vulnerability worldwide, producing disability and mortality, no study to date has assessed this protozoal infection in persons experiencing homelessness. Accordingly, the present study aimed to assess anti-T. cruzi antibodies by Wiener Chagatest ELISA recombinant v.3.0 in serum samples of persons experiencing homelessness and related shelter workers in São Paulo, a city with reported vectors but no recent autochthonous case report. Overall, seropositivity to T. cruzi resulted in three of 203 (1.5%) persons experiencing homelessness and two of 87 (2.3%) shelter workers, with similar seroprevalence, likely associated with their past social vulnerability. Although the seropositivity in persons experiencing homelessness and shelter workers was within 0 to 25.1% seroprevalence for chronic Chagas disease in the general Brazilian population, the disease has almost decreased 2-fold from the 1980s to 2000s, and such a wide range may not reflect the local disease status. In addition, the authors hypothesized that the similar seroprevalence and exposure between homeless persons and shelter workers herein may be more associated with shared past and present low-income social vulnerability than migratory movements, which may also include infection by sharing injecting drugs, vertical transmission, or blood transfusion. Thus, future studies are needed to confirm the active transmission of Chagas disease in São Paulo city. Moreover, Chagas disease should be considered as differential diagnosis in homeless persons and shelter workers, even in major disease-free Brazilian or other worldwide cities, mostly due to early exposure and vulnerable living conditions.Chagas DiseaseEpidemiologyHealth Inequitieshomeless peopleSocial VulnerabilityEnfermedad de ChagasEpidemiologíaInequidades en SaludPersonas con Mala ViviendaVulnerabilidad SocialMaladie de ChagasÉpidémiologieInégalités en matière de santéVulnérabilité socialeDoença de ChagasEpidemiologiaIniquidades em SaúdePessoas sem-TetoVulnerabilidade Socialinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.en_US.fl_str_mv Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
title Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
spellingShingle Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
Kmetiuk, Louise Bach
Chagas Disease
Epidemiology
Health Inequities
homeless people
Social Vulnerability
Enfermedad de Chagas
Epidemiología
Inequidades en Salud
Personas con Mala Vivienda
Vulnerabilidad Social
Maladie de Chagas
Épidémiologie
Inégalités en matière de santé
Vulnérabilité sociale
Doença de Chagas
Epidemiologia
Iniquidades em Saúde
Pessoas sem-Teto
Vulnerabilidade Social
title_short Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
title_full Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
title_fullStr Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
title_full_unstemmed Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
title_sort Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil
author Kmetiuk, Louise Bach
author_facet Kmetiuk, Louise Bach
Gonçalves, Gustavo
Couto, Anahi Chechia do
Biondo, Alexander Welker
Figueiredo, Fabiano Borges
author_role author
author2 Gonçalves, Gustavo
Couto, Anahi Chechia do
Biondo, Alexander Welker
Figueiredo, Fabiano Borges
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Kmetiuk, Louise Bach
Gonçalves, Gustavo
Couto, Anahi Chechia do
Biondo, Alexander Welker
Figueiredo, Fabiano Borges
dc.subject.en.en_US.fl_str_mv Chagas Disease
Epidemiology
Health Inequities
homeless people
Social Vulnerability
topic Chagas Disease
Epidemiology
Health Inequities
homeless people
Social Vulnerability
Enfermedad de Chagas
Epidemiología
Inequidades en Salud
Personas con Mala Vivienda
Vulnerabilidad Social
Maladie de Chagas
Épidémiologie
Inégalités en matière de santé
Vulnérabilité sociale
Doença de Chagas
Epidemiologia
Iniquidades em Saúde
Pessoas sem-Teto
Vulnerabilidade Social
dc.subject.es.en_US.fl_str_mv Enfermedad de Chagas
Epidemiología
Inequidades en Salud
Personas con Mala Vivienda
Vulnerabilidad Social
dc.subject.fr.en_US.fl_str_mv Maladie de Chagas
Épidémiologie
Inégalités en matière de santé
Vulnérabilité sociale
dc.subject.decs.en_US.fl_str_mv Doença de Chagas
Epidemiologia
Iniquidades em Saúde
Pessoas sem-Teto
Vulnerabilidade Social
description Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Celular. Curitiba, PR, Brasil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-04-17T13:07:23Z
dc.date.available.fl_str_mv 2023-04-17T13:07:23Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv KMETIUK, Louise Bach et al. Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil. Front. Public Health 11:1125028, p. 1–4, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/57823
dc.identifier.issn.en_US.fl_str_mv 2296-2565
dc.identifier.doi.none.fl_str_mv http://doi.org/10.3389/fpubh.2023.1125028
identifier_str_mv KMETIUK, Louise Bach et al. Serosurvey of Trypanosoma cruzi in persons experiencing homelessness and shelter workers of Brazil. Front. Public Health 11:1125028, p. 1–4, 2023.
2296-2565
url https://www.arca.fiocruz.br/handle/icict/57823
http://doi.org/10.3389/fpubh.2023.1125028
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
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instname:Fundação Oswaldo Cruz (FIOCRUZ)
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/57823/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/57823/2/fpubh-11-1125028OK.pdf
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