Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research

Detalhes bibliográficos
Autor(a) principal: Grossman, Cynthia I.
Data de Publicação: 2016
Outros Autores: Ross, Anna Laura, Auerbach, Judith D., Ananworanich, Jintanat, Dubé, Karine, Tucker, Joseph D., Noseda, Veronica, Possas, Cristina, Rausch, Dianne M., The International AIDS Society
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32284
Resumo: The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.
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spelling Grossman, Cynthia I.Ross, Anna LauraAuerbach, Judith D.Ananworanich, JintanatDubé, KarineTucker, Joseph D.Noseda, VeronicaPossas, CristinaRausch, Dianne M.The International AIDS Society2019-03-28T18:00:25Z2019-03-28T18:00:25Z2016GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016.1878-4380https://www.arca.fiocruz.br/handle/icict/3228410.1016/j.tim.2015.10.011The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.Institutos Nacionais de Saúde Mental. Institutos Nacionais de Saúde. Bethesda, EUA.ANRS. Paris, France.Universidade da Califórnia, São Francisco. Departamento de Medicina, Faculdade de Medicina. Centro de Estudos de Prevenção da AIDS. São Francisco, EUA.A Fundação Henry M. Jackson para o Avanço da Medicina Militar. Bethesda, EUA.Instituto de Saúde Global e Doenças Infecciosas. Genetic Medicine Buildin. Colaboradora dos Pesquisadores de Erradicação da AIDS. Chapel Hill, EUA.UNC Project-China, 2 Lujing Road, Guangzhou, China / Universidade da Carolina do Norte. Chapel Hill, EUA.Sidaction. Paris, França.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Institutos Nacionais de Saúde Mental. Institutos Nacionais de Saúde. Bethesda, EUA.engTowards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Researchinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHIV cureCost-effectivenessEthicsMultidisciplinaryPublic understanding of scienceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32284/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALF120-nihms741604.pdfapplication/pdf376861https://www.arca.fiocruz.br/bitstream/icict/32284/2/F120-nihms741604.pdfe2c850029c8be15aabcc8ec4d104c8eeMD52TEXTF120-nihms741604.pdf.txtF120-nihms741604.pdf.txtExtracted texttext/plain37094https://www.arca.fiocruz.br/bitstream/icict/32284/3/F120-nihms741604.pdf.txtd64b0bececa60b4138ce358c9855ceceMD53icict/322842019-04-04 02:03:22.006oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-04-04T05:03:22Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
title Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
spellingShingle Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
Grossman, Cynthia I.
HIV cure
Cost-effectiveness
Ethics
Multidisciplinary
Public understanding of science
title_short Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
title_full Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
title_fullStr Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
title_full_unstemmed Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
title_sort Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
author Grossman, Cynthia I.
author_facet Grossman, Cynthia I.
Ross, Anna Laura
Auerbach, Judith D.
Ananworanich, Jintanat
Dubé, Karine
Tucker, Joseph D.
Noseda, Veronica
Possas, Cristina
Rausch, Dianne M.
The International AIDS Society
author_role author
author2 Ross, Anna Laura
Auerbach, Judith D.
Ananworanich, Jintanat
Dubé, Karine
Tucker, Joseph D.
Noseda, Veronica
Possas, Cristina
Rausch, Dianne M.
The International AIDS Society
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Grossman, Cynthia I.
Ross, Anna Laura
Auerbach, Judith D.
Ananworanich, Jintanat
Dubé, Karine
Tucker, Joseph D.
Noseda, Veronica
Possas, Cristina
Rausch, Dianne M.
The International AIDS Society
dc.subject.en.pt_BR.fl_str_mv HIV cure
Cost-effectiveness
Ethics
Multidisciplinary
Public understanding of science
topic HIV cure
Cost-effectiveness
Ethics
Multidisciplinary
Public understanding of science
description The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2019-03-28T18:00:25Z
dc.date.available.fl_str_mv 2019-03-28T18:00:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32284
dc.identifier.issn.pt_BR.fl_str_mv 1878-4380
dc.identifier.doi.none.fl_str_mv 10.1016/j.tim.2015.10.011
identifier_str_mv GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016.
1878-4380
10.1016/j.tim.2015.10.011
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