Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/32284 |
Resumo: | The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community. |
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Grossman, Cynthia I.Ross, Anna LauraAuerbach, Judith D.Ananworanich, JintanatDubé, KarineTucker, Joseph D.Noseda, VeronicaPossas, CristinaRausch, Dianne M.The International AIDS Society2019-03-28T18:00:25Z2019-03-28T18:00:25Z2016GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016.1878-4380https://www.arca.fiocruz.br/handle/icict/3228410.1016/j.tim.2015.10.011The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.Institutos Nacionais de Saúde Mental. Institutos Nacionais de Saúde. Bethesda, EUA.ANRS. Paris, France.Universidade da Califórnia, São Francisco. Departamento de Medicina, Faculdade de Medicina. Centro de Estudos de Prevenção da AIDS. São Francisco, EUA.A Fundação Henry M. Jackson para o Avanço da Medicina Militar. Bethesda, EUA.Instituto de Saúde Global e Doenças Infecciosas. Genetic Medicine Buildin. Colaboradora dos Pesquisadores de Erradicação da AIDS. Chapel Hill, EUA.UNC Project-China, 2 Lujing Road, Guangzhou, China / Universidade da Carolina do Norte. Chapel Hill, EUA.Sidaction. Paris, França.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Institutos Nacionais de Saúde Mental. Institutos Nacionais de Saúde. Bethesda, EUA.engTowards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Researchinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHIV cureCost-effectivenessEthicsMultidisciplinaryPublic understanding of scienceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32284/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALF120-nihms741604.pdfapplication/pdf376861https://www.arca.fiocruz.br/bitstream/icict/32284/2/F120-nihms741604.pdfe2c850029c8be15aabcc8ec4d104c8eeMD52TEXTF120-nihms741604.pdf.txtF120-nihms741604.pdf.txtExtracted texttext/plain37094https://www.arca.fiocruz.br/bitstream/icict/32284/3/F120-nihms741604.pdf.txtd64b0bececa60b4138ce358c9855ceceMD53icict/322842019-04-04 02:03:22.006oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-04-04T05:03:22Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
title |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
spellingShingle |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research Grossman, Cynthia I. HIV cure Cost-effectiveness Ethics Multidisciplinary Public understanding of science |
title_short |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
title_full |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
title_fullStr |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
title_full_unstemmed |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
title_sort |
Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research |
author |
Grossman, Cynthia I. |
author_facet |
Grossman, Cynthia I. Ross, Anna Laura Auerbach, Judith D. Ananworanich, Jintanat Dubé, Karine Tucker, Joseph D. Noseda, Veronica Possas, Cristina Rausch, Dianne M. The International AIDS Society |
author_role |
author |
author2 |
Ross, Anna Laura Auerbach, Judith D. Ananworanich, Jintanat Dubé, Karine Tucker, Joseph D. Noseda, Veronica Possas, Cristina Rausch, Dianne M. The International AIDS Society |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Grossman, Cynthia I. Ross, Anna Laura Auerbach, Judith D. Ananworanich, Jintanat Dubé, Karine Tucker, Joseph D. Noseda, Veronica Possas, Cristina Rausch, Dianne M. The International AIDS Society |
dc.subject.en.pt_BR.fl_str_mv |
HIV cure Cost-effectiveness Ethics Multidisciplinary Public understanding of science |
topic |
HIV cure Cost-effectiveness Ethics Multidisciplinary Public understanding of science |
description |
The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2019-03-28T18:00:25Z |
dc.date.available.fl_str_mv |
2019-03-28T18:00:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/32284 |
dc.identifier.issn.pt_BR.fl_str_mv |
1878-4380 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.tim.2015.10.011 |
identifier_str_mv |
GROSSMAN, Cynthia I. et al. Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research. Trends In Microbiology, Cambridge, v. 24, n. 1, p. 5-11, 2016. 1878-4380 10.1016/j.tim.2015.10.011 |
url |
https://www.arca.fiocruz.br/handle/icict/32284 |
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eng |
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eng |
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openAccess |
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