Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)

Detalhes bibliográficos
Autor(a) principal: Andrade, Zilton de Araújo
Data de Publicação: 1984
Outros Autores: Andrade, Sonia Gumes, Sadigursky, Moysés
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/16448
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil
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spelling Andrade, Zilton de AraújoAndrade, Sonia GumesSadigursky, Moysés2016-12-06T16:54:52Z2016-12-06T16:54:52Z1984ANDRADE, Z. A.; ANDRADE, S. G.; SADIGURSKI, M. Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi). Journal of Pathology, v. 143, p. 93-101, 1984.0022-3417https://www.arca.fiocruz.br/handle/icict/16448engWileyDoença de ChagasMiocarditeTecido condutorConducting tissueChagas’ diseaseMyocarditisDamage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, BrasilThe consequences of acute inflammatory damage and chronic repair in the conducting system of the canine heart were observed after experimental Trypanosoma cruzi infection of young dogs. Acute infection lasted for 18-25 days and caused hyaline and lytic necrosis of the atrio-ventricular conducting fibres, the sinus node and the neurons in the cardiac para-sympathetic ganglia. Dogs that survived acute disease were examined after periods from 8 months to 3 years. Three main types of healing were found in the conducting system: fibrosis (diffuse and/or focal), sclero-atrophy and fatty infiltration. No signs of active chronic inflammation were present, although small focal residual accumulations of mononuclear cells were present in some animals. No evident electrocardiographic alterations were elicited by the presence of such cicatricial lesions. The animal model appears worthwhile for the study of the healing process in conducting tissue of the heart and for the better understanding of the asymptomatic phase of T. cruzi infection in man.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16448/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndrade, S.G. Demage and healing....pdfAndrade, S.G. Demage and healing....pdfapplication/pdf1064271https://www.arca.fiocruz.br/bitstream/icict/16448/2/Andrade%2c%20S.G.%20Demage%20and%20healing....pdf1775a3ed3ec4671a55403161120ebf21MD52TEXTAndrade, S.G. Demage and healing....pdf.txtAndrade, S.G. 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dc.title.pt_BR.fl_str_mv Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
title Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
spellingShingle Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
Andrade, Zilton de Araújo
Doença de Chagas
Miocardite
Tecido condutor
Conducting tissue
Chagas’ disease
Myocarditis
title_short Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
title_full Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
title_fullStr Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
title_full_unstemmed Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
title_sort Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi)
author Andrade, Zilton de Araújo
author_facet Andrade, Zilton de Araújo
Andrade, Sonia Gumes
Sadigursky, Moysés
author_role author
author2 Andrade, Sonia Gumes
Sadigursky, Moysés
author2_role author
author
dc.contributor.author.fl_str_mv Andrade, Zilton de Araújo
Andrade, Sonia Gumes
Sadigursky, Moysés
dc.subject.other.pt_BR.fl_str_mv Doença de Chagas
Miocardite
Tecido condutor
topic Doença de Chagas
Miocardite
Tecido condutor
Conducting tissue
Chagas’ disease
Myocarditis
dc.subject.en.pt_BR.fl_str_mv Conducting tissue
Chagas’ disease
Myocarditis
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil
publishDate 1984
dc.date.issued.fl_str_mv 1984
dc.date.accessioned.fl_str_mv 2016-12-06T16:54:52Z
dc.date.available.fl_str_mv 2016-12-06T16:54:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Z. A.; ANDRADE, S. G.; SADIGURSKI, M. Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi). Journal of Pathology, v. 143, p. 93-101, 1984.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/16448
dc.identifier.issn.pt_BR.fl_str_mv 0022-3417
identifier_str_mv ANDRADE, Z. A.; ANDRADE, S. G.; SADIGURSKI, M. Damage and healing in the conducting tissue of the heart (an experimental study in dogs infected with Trypanosoma Cruzi). Journal of Pathology, v. 143, p. 93-101, 1984.
0022-3417
url https://www.arca.fiocruz.br/handle/icict/16448
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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