Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil

Detalhes bibliográficos
Autor(a) principal: Carvalho, Janaína de Pina
Data de Publicação: 2021
Outros Autores: Assis, Tália Machado de, Simões, Taynãna César, Cota, Gláucia Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51269
Resumo: Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil.
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spelling Carvalho, Janaína de PinaAssis, Tália Machado deSimões, Taynãna CésarCota, Gláucia Fernandes2022-02-17T14:16:20Z2022-02-17T14:16:20Z2021CARVALHO, Janaína de Pina et al. Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil. Rev Soc Bras Med Trop., v. 54, e04542020, 2021. doi: 10.1590/0037-8682-0454-2020. eCollection 2021.0037-8682https://www.arca.fiocruz.br/handle/icict/51269engSociedade Brasileira de Medicina TropicalEstimating direct costs of the treatment for mucosal leishmaniasis in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil./Centro Federal de Educação Tecnológica de Minas Gerais. Contagem, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil.INTRODUCTION: The objective of this study was to estimate the direct medical costs of the treatment for mucosal leishmaniasis (ML) using three therapeutic approaches in the Brazilian context. METHODS: We performed this economic assessment from the perspective of the Brazilian public healthcare system. The following therapeutic approaches were evaluated: meglumine antimoniate, liposomal amphotericin B, and miltefosine. Direct medical costs were estimated considering four treatment components: a) drug, b) combined medical products, c) procedures, and d) complementary tests. RESULTS: Treatment with meglumine antimoniate had the lowest average cost per patient (US$ 167.66), followed by miltefosine (US$ 259.92) in the outpatient treatment regimen. The average cost of treatment with liposomal amphotericin B was US$ 715.35 both in inpatient regimen. In all estimates, the drugs accounted for more than 60% of the total cost for each treatment approach. CONCLUSIONS: These results demonstrate the marked differences in costs between the therapeutic alternatives for ML. In addition to efficacy rates and costs related to adverse events, our data have the potential to support a complete cost-effectiveness study in the future. Complete analyses comparing costs and benefits for interventions will assist health managers in choosing drugs for ML treatment in Brazil as well as in establishing effective public health policies.Mucocutaneous leishmaniasisCost analysisDrug therapyMeglumine antimoniateLiposomal amphotericin BMiltefosineinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/51269/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALEstimating direct costs of the treatment for mucosal leishmaniasis in Brazil.pdfEstimating direct costs of the treatment for mucosal leishmaniasis in Brazil.pdfapplication/pdf6775177https://www.arca.fiocruz.br/bitstream/icict/51269/2/Estimating%20direct%20costs%20of%20the%20treatment%20for%20mucosal%20leishmaniasis%20in%20Brazil.pdf00b7b73b0f1cc79e8366ebd332ff063dMD52icict/512692022-02-17 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dc.title.pt_BR.fl_str_mv Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
title Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
spellingShingle Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
Carvalho, Janaína de Pina
Mucocutaneous leishmaniasis
Cost analysis
Drug therapy
Meglumine antimoniate
Liposomal amphotericin B
Miltefosine
title_short Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
title_full Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
title_fullStr Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
title_full_unstemmed Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
title_sort Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil
author Carvalho, Janaína de Pina
author_facet Carvalho, Janaína de Pina
Assis, Tália Machado de
Simões, Taynãna César
Cota, Gláucia Fernandes
author_role author
author2 Assis, Tália Machado de
Simões, Taynãna César
Cota, Gláucia Fernandes
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvalho, Janaína de Pina
Assis, Tália Machado de
Simões, Taynãna César
Cota, Gláucia Fernandes
dc.subject.en.pt_BR.fl_str_mv Mucocutaneous leishmaniasis
Cost analysis
Drug therapy
Meglumine antimoniate
Liposomal amphotericin B
Miltefosine
topic Mucocutaneous leishmaniasis
Cost analysis
Drug therapy
Meglumine antimoniate
Liposomal amphotericin B
Miltefosine
description Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-17T14:16:20Z
dc.date.available.fl_str_mv 2022-02-17T14:16:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CARVALHO, Janaína de Pina et al. Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil. Rev Soc Bras Med Trop., v. 54, e04542020, 2021. doi: 10.1590/0037-8682-0454-2020. eCollection 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51269
dc.identifier.issn.pt_BR.fl_str_mv 0037-8682
identifier_str_mv CARVALHO, Janaína de Pina et al. Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil. Rev Soc Bras Med Trop., v. 54, e04542020, 2021. doi: 10.1590/0037-8682-0454-2020. eCollection 2021.
0037-8682
url https://www.arca.fiocruz.br/handle/icict/51269
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51269/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/51269/2/Estimating%20direct%20costs%20of%20the%20treatment%20for%20mucosal%20leishmaniasis%20in%20Brazil.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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