Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Amanda Almeida
Data de Publicação: 2012
Outros Autores: Pinto Junior, Vitor Laerte, Lazéra, Márcia dos Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42371
Resumo: Vitor Laerte Pinto Junior - Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
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spelling Albuquerque, Amanda AlmeidaPinto Junior, Vitor LaerteLazéra, Márcia dos Santos2020-07-24T12:13:16Z2020-07-24T12:13:16Z2012ALBUQUERQUE, Amanda Almeida; PINTO JUNIOR, Vitor Laerte; LAZÉRA, Márcia dos Santos. Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report. Revista de Medicina e Saúde de Brasília, Brasília, v. 1, n. 3, p. 137-142, 2012.2238-5339https://www.arca.fiocruz.br/handle/icict/42371Vitor Laerte Pinto Junior - Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.A criptococose é uma infecção fúngica causada pelo agente encapsulado Cryptococcus neoformans, sendo a variante gattii responsável pela infecção em imunocompetentes e a variante grubii pela infecção em imunodeprimidos. Infecções por C. neoformans têm sido cada vez mais reconhecidas como uma ameaça significativa para a saúde das populações imunocomprometidas em todo o mundo, especialmente em indivíduos com AIDS. O agente é adquirido por inalação e dissemina-se por via hematogênica atingindo o sistema nervoso central (SNC), a pele, entre outros sistemas. Manifestações cutâneas ocorrem em 10% a 15% de todos os casos de criptococose sistêmica e é frequentemente associada com infecção sistêmica. Nesse relato, descrevemos um caso de um paciente de 28 anos, soropositivo para vírus da imunodeficiência humana (HIV), em que o acentuado envolvimento cutâneo fornece a suspeita clínica de criptococose disseminada, confirmada pelas análises do líquido cefalorraquidiano e do histopatológico da lesão. Apesar do reconhecimento e tratamento correto da micose, o paciente morreu após três dias de permanência no hospital, o que reforça a gravidade dessa condição e a necessidade da suspeita clínica na presença de lesões cutâneas típicas.Cryptococcosis is a fungal infection caused by Cryptococcus neoformans encapsulated agent, being the variant gattii responsible for infection in immunocompetents and the variants grubii for infection in immunodeficients. C. neoformans infection have been increasingly recognized as a significant threat to the health of immune compromised populations throughout the world, especially in individuals with AIDS. The agent is acquired by inhalation the disease spreads through the hematogenic way affecting the central nervous system (CNS), skin, among other systems. Cutaneous manifestations occur in 10-15% of all cases of systemic cryptococcosis and is often associated with systemic infection. In this report we describe a case of a patient of 28 years, with human immunodeficiency virus (HIV) positive, in which markedly cutaneous involvement provided the clinical suspicious of disseminated cryptococcosis, confirmed with analysis cerebrospinal fluid (CSF) and lesion histopathology analysis. Despite the recognition and correct treatment of the mycosis, the patient died after three days of hospital stay, reinforcing the severity of this condition and the need of clinical suspicious in the presence of typical cutaneous lesions.Universidade Católica de Brasília. Brasília, DF, Brasil.Universidade Católica de Brasília. Brasília, DF, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.engUniversidade Católica de BrasíliaAcquired Immunodeficiency SyndromeCryptococcosisAmphotericin BMycosesCriptococoseAIDSAnfotericina BCryptococcosisAIDSAmphotericin BSíndrome de Imunodeficiência AdquiridaCriptococoseAnfotericina BMicosesCutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case reportManifestação cutânea da criptococose em paciente com síndrome da imunodeficiência adquirida (SIDA): relato de casoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
dc.title.alternative.pt_BR.fl_str_mv Manifestação cutânea da criptococose em paciente com síndrome da imunodeficiência adquirida (SIDA): relato de caso
title Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
spellingShingle Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
Albuquerque, Amanda Almeida
Acquired Immunodeficiency Syndrome
Cryptococcosis
Amphotericin B
Mycoses
Criptococose
AIDS
Anfotericina B
Cryptococcosis
AIDS
Amphotericin B
Síndrome de Imunodeficiência Adquirida
Criptococose
Anfotericina B
Micoses
title_short Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
title_full Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
title_fullStr Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
title_full_unstemmed Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
title_sort Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report
author Albuquerque, Amanda Almeida
author_facet Albuquerque, Amanda Almeida
Pinto Junior, Vitor Laerte
Lazéra, Márcia dos Santos
author_role author
author2 Pinto Junior, Vitor Laerte
Lazéra, Márcia dos Santos
author2_role author
author
dc.contributor.author.fl_str_mv Albuquerque, Amanda Almeida
Pinto Junior, Vitor Laerte
Lazéra, Márcia dos Santos
dc.subject.mesh.pt_BR.fl_str_mv Acquired Immunodeficiency Syndrome
Cryptococcosis
Amphotericin B
Mycoses
topic Acquired Immunodeficiency Syndrome
Cryptococcosis
Amphotericin B
Mycoses
Criptococose
AIDS
Anfotericina B
Cryptococcosis
AIDS
Amphotericin B
Síndrome de Imunodeficiência Adquirida
Criptococose
Anfotericina B
Micoses
dc.subject.other.pt_BR.fl_str_mv Criptococose
AIDS
Anfotericina B
dc.subject.en.pt_BR.fl_str_mv Cryptococcosis
AIDS
Amphotericin B
dc.subject.decs.pt_BR.fl_str_mv Síndrome de Imunodeficiência Adquirida
Criptococose
Anfotericina B
Micoses
description Vitor Laerte Pinto Junior - Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2020-07-24T12:13:16Z
dc.date.available.fl_str_mv 2020-07-24T12:13:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ALBUQUERQUE, Amanda Almeida; PINTO JUNIOR, Vitor Laerte; LAZÉRA, Márcia dos Santos. Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report. Revista de Medicina e Saúde de Brasília, Brasília, v. 1, n. 3, p. 137-142, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42371
dc.identifier.issn.pt_BR.fl_str_mv 2238-5339
identifier_str_mv ALBUQUERQUE, Amanda Almeida; PINTO JUNIOR, Vitor Laerte; LAZÉRA, Márcia dos Santos. Cutaneous manifestation of cryptococcosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report. Revista de Medicina e Saúde de Brasília, Brasília, v. 1, n. 3, p. 137-142, 2012.
2238-5339
url https://www.arca.fiocruz.br/handle/icict/42371
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Católica de Brasília
publisher.none.fl_str_mv Universidade Católica de Brasília
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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