The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS

Detalhes bibliográficos
Autor(a) principal: Paixão, Ariane Gomes
Data de Publicação: 2015
Outros Autores: Galhardo, Maria Clara Gutierrez, Almeida-Paes, Rodrigo, Nunes, Estevão Portela, Gonçalves, Marcelo Luiz Carvalho, Chequer, Gisele Larias, Lamas, Cristiane da Cruz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/34704
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.
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spelling Paixão, Ariane GomesGalhardo, Maria Clara GutierrezAlmeida-Paes, RodrigoNunes, Estevão PortelaGonçalves, Marcelo Luiz CarvalhoChequer, Gisele LariasLamas, Cristiane da Cruz2019-08-12T12:15:17Z2019-08-12T12:15:17Z2015PAIXÃO, Ariane Gomes et al. The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS. AIDS Research and Therapy, v. 12, p. 1-6, 2015.1742-6405https://www.arca.fiocruz.br/handle/icict/3470410.1186/s12981-015-0051-11742-6405)engBMCThe difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDSinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.Sporotrichosis is an infection caused by a dimorphic fungus of the Sporothrix schenckii complex. Host immunity is an important factor in the clinical manifestations of the disease. Deeply immunocompromised individuals, especially those infected with the Human Immunodeficiency Virus (HIV) and T CD4 counts < 350 cells/ul lymphocytes, may present with the systemic form of sporotrichosis. This report describes a case of disseminated sporotrichosis caused by S. brasiliensis in a patient with advanced AIDS. The skin, lungs, bones and central nervous system were affected. Medical treatment involved the administration of amphotericin B, terbinafine, itraconazole and posaconazole. Posaconazole was associated with the best clinical response and clearing of the fungus from the central nervous system.SporotrichosisAIDSAmphotericin BPosaconazoleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/34704/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Paixão_Ariane_etal_INI_2015.pdfve_Paixão_Ariane_etal_INI_2015.pdfapplication/pdf1720137https://www.arca.fiocruz.br/bitstream/icict/34704/2/ve_Paix%c3%a3o_Ariane_etal_INI_2015.pdf0c2a41bfca9b43fe6b5838f981ea8e7fMD52TEXTve_Paixão_Ariane_etal_INI_2015.pdf.txtve_Paixão_Ariane_etal_INI_2015.pdf.txtExtracted texttext/plain22336https://www.arca.fiocruz.br/bitstream/icict/34704/3/ve_Paix%c3%a3o_Ariane_etal_INI_2015.pdf.txt8c6b92efe1c19bee8136d3fa92629e70MD53icict/347042019-08-13 02:02:32.746oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-08-13T05:02:32Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
title The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
spellingShingle The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
Paixão, Ariane Gomes
Sporotrichosis
AIDS
Amphotericin B
Posaconazole
title_short The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
title_full The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
title_fullStr The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
title_full_unstemmed The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
title_sort The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS
author Paixão, Ariane Gomes
author_facet Paixão, Ariane Gomes
Galhardo, Maria Clara Gutierrez
Almeida-Paes, Rodrigo
Nunes, Estevão Portela
Gonçalves, Marcelo Luiz Carvalho
Chequer, Gisele Larias
Lamas, Cristiane da Cruz
author_role author
author2 Galhardo, Maria Clara Gutierrez
Almeida-Paes, Rodrigo
Nunes, Estevão Portela
Gonçalves, Marcelo Luiz Carvalho
Chequer, Gisele Larias
Lamas, Cristiane da Cruz
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paixão, Ariane Gomes
Galhardo, Maria Clara Gutierrez
Almeida-Paes, Rodrigo
Nunes, Estevão Portela
Gonçalves, Marcelo Luiz Carvalho
Chequer, Gisele Larias
Lamas, Cristiane da Cruz
dc.subject.en.pt_BR.fl_str_mv Sporotrichosis
AIDS
Amphotericin B
Posaconazole
topic Sporotrichosis
AIDS
Amphotericin B
Posaconazole
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2019-08-12T12:15:17Z
dc.date.available.fl_str_mv 2019-08-12T12:15:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv PAIXÃO, Ariane Gomes et al. The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS. AIDS Research and Therapy, v. 12, p. 1-6, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/34704
dc.identifier.issn.pt_BR.fl_str_mv 1742-6405
dc.identifier.doi.none.fl_str_mv 10.1186/s12981-015-0051-1
dc.identifier.eissn.none.fl_str_mv 1742-6405)
identifier_str_mv PAIXÃO, Ariane Gomes et al. The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS. AIDS Research and Therapy, v. 12, p. 1-6, 2015.
1742-6405
10.1186/s12981-015-0051-1
1742-6405)
url https://www.arca.fiocruz.br/handle/icict/34704
dc.language.iso.fl_str_mv eng
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