Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections

Detalhes bibliográficos
Autor(a) principal: Jansen, Ana M.
Data de Publicação: 1994
Outros Autores: Madeira, Fatima B., Deane, Maria P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43635
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.
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spelling Jansen, Ana M.Madeira, Fatima B.Deane, Maria P.2020-09-28T12:18:14Z2020-09-28T12:18:14Z1994JANSEN, Ana M.; MADEIRA, Fatima B.; DEANE, Maria P. Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 1, p. 41-45, Jan./Mar. 1994.0074-0276https://www.arca.fiocruz.br/handle/icict/4363510.1590/S0074-027619940001000081678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Trypanosoma cruziInfecçãoDidelphis marsupialisGambáAusência de transmissão neonatalProteção por anticorpos maternosTrypanosoma cruziInfectionDidelphis marsupialisOpossumProtection by maternal antibodiesAbsence of neonatal transmissionTrypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infectionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.The high rate of natural Trypanosoma cruzi infection found in opossums does not always correlate with appreciable densities of local triatomid populations. One alternative method which might bypass the invertebrate vector is direct transmission from mother to offspring. This possibility was investigated in five T. cruzi infected females and their litters (24 young). The influence of maternal antibodies transferred via lactation, on the course of experimental infection, was also examined. Our results show that neonatal transmission is probably not responsible for the high rate of natural T. cruzi infection among opossums. In addition antibodies of maternal origin confer a partial protection to the young. This was demonstrated by the finding of a double prepatency period and 4,5 fold lower levels of circulating parasites, in experimentally infected pouch young from infected as compared to control uninfected mothes. On the other hand, the duration of patent parasitemia was twice as long as that observed in the control group.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/43635/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAnaJansen_MariaDeane_etal_IOC_1994.pdfAnaJansen_MariaDeane_etal_IOC_1994.pdfapplication/pdf289955https://www.arca.fiocruz.br/bitstream/icict/43635/2/AnaJansen_MariaDeane_etal_IOC_1994.pdf2c18d5ca2eca7b77eaebb155309517eeMD52TEXTAnaJansen_MariaDeane_etal_IOC_1994.pdf.txtAnaJansen_MariaDeane_etal_IOC_1994.pdf.txtExtracted texttext/plain5https://www.arca.fiocruz.br/bitstream/icict/43635/3/AnaJansen_MariaDeane_etal_IOC_1994.pdf.txtcc9067c2ee470dc248b14b194209a34eMD53icict/436352020-09-29 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dc.title.pt_BR.fl_str_mv Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
title Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
spellingShingle Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
Jansen, Ana M.
Trypanosoma cruzi
Infecção
Didelphis marsupialis
Gambá
Ausência de transmissão neonatal
Proteção por anticorpos maternos
Trypanosoma cruzi
Infection
Didelphis marsupialis
Opossum
Protection by maternal antibodies
Absence of neonatal transmission
title_short Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
title_full Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
title_fullStr Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
title_full_unstemmed Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
title_sort Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections
author Jansen, Ana M.
author_facet Jansen, Ana M.
Madeira, Fatima B.
Deane, Maria P.
author_role author
author2 Madeira, Fatima B.
Deane, Maria P.
author2_role author
author
dc.contributor.author.fl_str_mv Jansen, Ana M.
Madeira, Fatima B.
Deane, Maria P.
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Infecção
Didelphis marsupialis
Gambá
Ausência de transmissão neonatal
Proteção por anticorpos maternos
topic Trypanosoma cruzi
Infecção
Didelphis marsupialis
Gambá
Ausência de transmissão neonatal
Proteção por anticorpos maternos
Trypanosoma cruzi
Infection
Didelphis marsupialis
Opossum
Protection by maternal antibodies
Absence of neonatal transmission
dc.subject.en.pt_BR.fl_str_mv Trypanosoma cruzi
Infection
Didelphis marsupialis
Opossum
Protection by maternal antibodies
Absence of neonatal transmission
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.
publishDate 1994
dc.date.issued.fl_str_mv 1994
dc.date.accessioned.fl_str_mv 2020-09-28T12:18:14Z
dc.date.available.fl_str_mv 2020-09-28T12:18:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv JANSEN, Ana M.; MADEIRA, Fatima B.; DEANE, Maria P. Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 1, p. 41-45, Jan./Mar. 1994.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43635
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761994000100008
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv JANSEN, Ana M.; MADEIRA, Fatima B.; DEANE, Maria P. Trypanosoma cruzi infection in the opossum Didelphis marsupialis: absence of neonatal transmission and protection by maternal antibodies in experimental infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 1, p. 41-45, Jan./Mar. 1994.
0074-0276
10.1590/S0074-02761994000100008
1678-8060
url https://www.arca.fiocruz.br/handle/icict/43635
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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