Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study

Detalhes bibliográficos
Autor(a) principal: Renke, Guilherme
Data de Publicação: 2022
Outros Autores: Gapanowicz, Débora Pinto, Pereira, Marcela Batista, Mattos, Fernanda, Ribeiro-Alves, Marcelo, Assad, Marcelo, Moreira, Annie Seixas Bello
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56392
Resumo: Brazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil / Nutrindo Ideais Performance and Nutrition Research Centre. Rio de Janeiro, RJ, Brazil.
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spelling Renke, GuilhermeGapanowicz, Débora PintoPereira, Marcela BatistaMattos, FernandaRibeiro-Alves, MarceloAssad, MarceloMoreira, Annie Seixas Bello2023-01-09T12:53:48Z2023-01-09T12:53:48Z2022RENKE, Guilherme et al. Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study. Cardiology and therapy, v. 11, n. 4, p. 575-587, 2022.2193-8261https://www.arca.fiocruz.br/handle/icict/5639210.1007/s40119-022-00282-6engSpringerLong-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBrazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil / Nutrindo Ideais Performance and Nutrition Research Centre. Rio de Janeiro, RJ, Brazil.Brazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil.Nutrindo Ideais Performance and Nutrition Research Centre. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Clementino Fraga Filho University Hospital. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Brazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil.Brazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil.Introduction: The management of patients with dyslipidemia (DLP) requires intensive medical follow-up as an essential part of treatment and to reduce the risk of cardiovascular (CV) outcomes. The aim of this study was to evaluate whether adherence to medical treatment changed the prevalence of CV disease events in a retrospective 7-year follow-up analysis. Methods: This retrospective study involved 92 patients divided into two groups according to their adherence: the REG group with 64 patients who had medical appointments from 2012 to 2018, and the DROP group, with 28 patients who had medical appointments in 2012 but did not complete regular appointments until 2018. Cox proportional hazard models were fitted to estimate hazard ratios associated with CV outcomes as primary endpoints. Results: We observed a total of 32 cases of acute myocardial infarction (AMI) in the study population, 17 (338.41 pY) in the REG group and 15 (62.97 pY) in the DROP group. An increased hazard of AMIs was observed in the DROP group compared with the REG group by follow-up time (p < 0.001). We found that previous events of AMI and congestive heart failure (CHF) were associated with progression to treatment dropout (p < 0.05) and that two drugs were considered a risk factor for treatment dropout, diuretics and fibrates (p < 0.05). Conclusions: A reduced hazard of AMI was observed in patients who complete a greater number of medical appointments and receive multidisciplinary treatment on a regular basis.Cardiovascular diseaseDyslipidemiaMultidisciplinary care teamMyocardial infarctioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56392/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLong-Term_Marcelo_Alves_etal_INI_2022.pdfLong-Term_Marcelo_Alves_etal_INI_2022.pdfapplication/pdf490723https://www.arca.fiocruz.br/bitstream/icict/56392/2/Long-Term_Marcelo_Alves_etal_INI_2022.pdf636c11a6b411da2a2c1e87addc5f64beMD52icict/563922023-01-09 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dc.title.en_US.fl_str_mv Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
title Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
spellingShingle Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
Renke, Guilherme
Cardiovascular disease
Dyslipidemia
Multidisciplinary care team
Myocardial infarction
title_short Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
title_full Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
title_fullStr Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
title_full_unstemmed Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
title_sort Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study
author Renke, Guilherme
author_facet Renke, Guilherme
Gapanowicz, Débora Pinto
Pereira, Marcela Batista
Mattos, Fernanda
Ribeiro-Alves, Marcelo
Assad, Marcelo
Moreira, Annie Seixas Bello
author_role author
author2 Gapanowicz, Débora Pinto
Pereira, Marcela Batista
Mattos, Fernanda
Ribeiro-Alves, Marcelo
Assad, Marcelo
Moreira, Annie Seixas Bello
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Renke, Guilherme
Gapanowicz, Débora Pinto
Pereira, Marcela Batista
Mattos, Fernanda
Ribeiro-Alves, Marcelo
Assad, Marcelo
Moreira, Annie Seixas Bello
dc.subject.en.en_US.fl_str_mv Cardiovascular disease
Dyslipidemia
Multidisciplinary care team
Myocardial infarction
topic Cardiovascular disease
Dyslipidemia
Multidisciplinary care team
Myocardial infarction
description Brazilian Ministry of Health. National Institute of Cardiology. Rio de Janeiro, RJ, Brazil / Nutrindo Ideais Performance and Nutrition Research Centre. Rio de Janeiro, RJ, Brazil.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-01-09T12:53:48Z
dc.date.available.fl_str_mv 2023-01-09T12:53:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv RENKE, Guilherme et al. Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study. Cardiology and therapy, v. 11, n. 4, p. 575-587, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56392
dc.identifier.issn.en_US.fl_str_mv 2193-8261
dc.identifier.doi.none.fl_str_mv 10.1007/s40119-022-00282-6
identifier_str_mv RENKE, Guilherme et al. Long-Term Association between Intensive Medical Treatment and the Incidence of Cardiovascular Outcomes in Patients with Dyslipidemia: an Observational Study. Cardiology and therapy, v. 11, n. 4, p. 575-587, 2022.
2193-8261
10.1007/s40119-022-00282-6
url https://www.arca.fiocruz.br/handle/icict/56392
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56392/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56392/2/Long-Term_Marcelo_Alves_etal_INI_2022.pdf
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