Extramedullary hematopoiesis in murine schistosomiasis mansoni

Detalhes bibliográficos
Autor(a) principal: Lenzi, Henrique Leonel
Data de Publicação: 1995
Outros Autores: Lenzi, Jane A., Rosman, F. C., Machado, Marcelo Pelajo, Mota, M., Panasco, Monica de Souza, Oliveira, Denise N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/4069
http://dx.doi.org/10.1590/S0074-02761995000200008
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
id CRUZ_13f550e16663809dd930d84d4a02250c
oai_identifier_str oai:www.arca.fiocruz.br:icict/4069
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Lenzi, Henrique LeonelLenzi, Jane A.Rosman, F. C.Machado, Marcelo PelajoMota, M.Panasco, Monica de SouzaOliveira, Denise N.2012-05-15T14:47:55Z2012-05-15T14:47:55Z1995LENZI H. L. et al. Extramedullary hematopoiesis in murine schistosomiasis mansoni. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.90, n.2, p.169-177. Apr 1995.0074-0276https://www.arca.fiocruz.br/handle/icict/4069http://dx.doi.org/10.1590/S0074-02761995000200008engFundação Oswaldo Cruz. Instituto Oswaldo CruzExtramedullary hematopoiesis in murine schistosomiasis mansoniinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.During Schistosoma mansoni infection, there is morphological evidence of involvement of various hematopoietic growth factors, which cause eosinophil, neutrophil, megakaryocytic and erythroid extramedullary foci in the liver, lymph nodes and omental and mesenteric milky spots. While the eosinophil metaplasia in the periphery of hepatic granulomas roughly reproduced the intensity of the medullary eosinopoiesis, the neutrophil metaplasia, on the contrary, was more intense during the period of neutrophil depression in the bone marrow. This fact suggests that extramedullary hematopoietic foci are locally regulated, and amplify and/or compensate the systemic hematopoietic response during the infection.CosinophilneutrophilMegakaryocyteHematopoiesisSchistosoma mansoniLymph nodesMilky spotsSchistosoma mansoniInfecçãoMegacariócitosHematopoeseLinfonodosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALxtramedullary hematopoiesis.pdfxtramedullary hematopoiesis.pdfapplication/pdf656652https://www.arca.fiocruz.br/bitstream/icict/4069/1/xtramedullary%20hematopoiesis.pdf843b8cb8870199b45e1b3e749e8078f1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/4069/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTxtramedullary hematopoiesis.pdf.txtxtramedullary hematopoiesis.pdf.txtExtracted texttext/plain9https://www.arca.fiocruz.br/bitstream/icict/4069/5/xtramedullary%20hematopoiesis.pdf.txt33f4f15a16a9843faf6a25d4f387b6fdMD55THUMBNAILxtramedullary hematopoiesis.pdf.jpgxtramedullary hematopoiesis.pdf.jpgGenerated Thumbnailimage/jpeg2599https://www.arca.fiocruz.br/bitstream/icict/4069/4/xtramedullary%20hematopoiesis.pdf.jpg40cb69e65c7e3a30de2cce9dd1fd7668MD54icict/40692018-04-06 09:06:44.439oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-04-06T12:06:44Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Extramedullary hematopoiesis in murine schistosomiasis mansoni
title Extramedullary hematopoiesis in murine schistosomiasis mansoni
spellingShingle Extramedullary hematopoiesis in murine schistosomiasis mansoni
Lenzi, Henrique Leonel
Cosinophil
neutrophil
Megakaryocyte
Hematopoiesis
Schistosoma mansoni
Lymph nodes
Milky spots
Schistosoma mansoni
Infecção
Megacariócitos
Hematopoese
Linfonodos
title_short Extramedullary hematopoiesis in murine schistosomiasis mansoni
title_full Extramedullary hematopoiesis in murine schistosomiasis mansoni
title_fullStr Extramedullary hematopoiesis in murine schistosomiasis mansoni
title_full_unstemmed Extramedullary hematopoiesis in murine schistosomiasis mansoni
title_sort Extramedullary hematopoiesis in murine schistosomiasis mansoni
author Lenzi, Henrique Leonel
author_facet Lenzi, Henrique Leonel
Lenzi, Jane A.
Rosman, F. C.
Machado, Marcelo Pelajo
Mota, M.
Panasco, Monica de Souza
Oliveira, Denise N.
author_role author
author2 Lenzi, Jane A.
Rosman, F. C.
Machado, Marcelo Pelajo
Mota, M.
Panasco, Monica de Souza
Oliveira, Denise N.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lenzi, Henrique Leonel
Lenzi, Jane A.
Rosman, F. C.
Machado, Marcelo Pelajo
Mota, M.
Panasco, Monica de Souza
Oliveira, Denise N.
dc.subject.en.pt_BR.fl_str_mv Cosinophil
neutrophil
Megakaryocyte
Hematopoiesis
Schistosoma mansoni
Lymph nodes
Milky spots
topic Cosinophil
neutrophil
Megakaryocyte
Hematopoiesis
Schistosoma mansoni
Lymph nodes
Milky spots
Schistosoma mansoni
Infecção
Megacariócitos
Hematopoese
Linfonodos
dc.subject.decs.pt_BR.fl_str_mv Schistosoma mansoni
Infecção
Megacariócitos
Hematopoese
Linfonodos
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
publishDate 1995
dc.date.issued.fl_str_mv 1995
dc.date.accessioned.fl_str_mv 2012-05-15T14:47:55Z
dc.date.available.fl_str_mv 2012-05-15T14:47:55Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LENZI H. L. et al. Extramedullary hematopoiesis in murine schistosomiasis mansoni. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.90, n.2, p.169-177. Apr 1995.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/4069
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1590/S0074-02761995000200008
identifier_str_mv LENZI H. L. et al. Extramedullary hematopoiesis in murine schistosomiasis mansoni. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.90, n.2, p.169-177. Apr 1995.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/4069
http://dx.doi.org/10.1590/S0074-02761995000200008
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/4069/1/xtramedullary%20hematopoiesis.pdf
https://www.arca.fiocruz.br/bitstream/icict/4069/2/license.txt
https://www.arca.fiocruz.br/bitstream/icict/4069/5/xtramedullary%20hematopoiesis.pdf.txt
https://www.arca.fiocruz.br/bitstream/icict/4069/4/xtramedullary%20hematopoiesis.pdf.jpg
bitstream.checksum.fl_str_mv 843b8cb8870199b45e1b3e749e8078f1
e095249ac7cacefbfe39684dfe45e706
33f4f15a16a9843faf6a25d4f387b6fd
40cb69e65c7e3a30de2cce9dd1fd7668
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008889014124544