HPV vaccines: a controversial issue?

Detalhes bibliográficos
Autor(a) principal: Nicol, Alcina Frederica
Data de Publicação: 2016
Outros Autores: Andrade, Cecília Vianna de, Russomano, Fábio Bastos, Rodrigues, Luana Lorena Silva, Oliveira, N. S., Provance Junior, David William
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13963
Resumo: Laboratory of Interdisciplinary Medical Research (LIPMED)
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spelling Nicol, Alcina FredericaAndrade, Cecília Vianna deRussomano, Fábio BastosRodrigues, Luana Lorena SilvaOliveira, N. S.Provance Junior, David William2016-04-25T15:56:52Z2016-04-25T15:56:52Z2016NICOL, Alcina Frederica et al. HPV vaccines: a controversial issue?. Brazilian Journal of Medical and Biological Research, v. 49, n. 5, p. 1-5, 2016.0100-879Xhttps://www.arca.fiocruz.br/handle/icict/1396310.1590/1414-431X201550601414-431XLaboratory of Interdisciplinary Medical Research (LIPMED)Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Universidade Federal do Oeste do Pará. Instituto de Saúde Coletiva. Santarém, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil / Universidade Federal Fluminense. Hospital Universitário Antonio Pedro. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil.Controversy still exists over whether the benefits of the available HPV vaccines outweigh the risks and this has suppressed uptake of the HPV vaccines in comparison to other vaccines. Concerns about HPV vaccine safety have led some physicians, healthcare officials and parents to withhold the recommended vaccination from the target population. The most common reason for not administering the prophylactic HPV vaccines are concerns over adverse effects. The aim of this review is the assessment of peer-reviewed scientific data related to measurable outcomes from the use of HPV vaccines throughout the world with focused attention on the potential adverse effects. We found that the majority of studies continue to suggest a positive risk-benefit from vaccination against HPV, with minimal documented adverse effects, which is consistent with other vaccines. However, much of the published scientific data regarding the safety of HPV vaccines appears to originate from within the financially competitive HPV vaccine market. We advocate a more independent monitoring system for vaccine immunogenicity and adverse effects to address potential conflicts of interest with regular systematic literature reviews by qualified individuals to vigilantly assess and communicate adverse effects associated with HPV vaccination. Finally, our evaluation suggests that an expanded use of HPV vaccine into more diverse populations, particularly those living in low-resource settings, would provide numerous health and social benefits.engAssociação Brasileira de Divulgação CientíficaPapillomavirus HumanoVacinaçãoEventos adversosHuman papillomavirusVaccinationAdverse eventsHPV vaccines: a controversial issue?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv HPV vaccines: a controversial issue?
title HPV vaccines: a controversial issue?
spellingShingle HPV vaccines: a controversial issue?
Nicol, Alcina Frederica
Papillomavirus Humano
Vacinação
Eventos adversos
Human papillomavirus
Vaccination
Adverse events
title_short HPV vaccines: a controversial issue?
title_full HPV vaccines: a controversial issue?
title_fullStr HPV vaccines: a controversial issue?
title_full_unstemmed HPV vaccines: a controversial issue?
title_sort HPV vaccines: a controversial issue?
author Nicol, Alcina Frederica
author_facet Nicol, Alcina Frederica
Andrade, Cecília Vianna de
Russomano, Fábio Bastos
Rodrigues, Luana Lorena Silva
Oliveira, N. S.
Provance Junior, David William
author_role author
author2 Andrade, Cecília Vianna de
Russomano, Fábio Bastos
Rodrigues, Luana Lorena Silva
Oliveira, N. S.
Provance Junior, David William
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Nicol, Alcina Frederica
Andrade, Cecília Vianna de
Russomano, Fábio Bastos
Rodrigues, Luana Lorena Silva
Oliveira, N. S.
Provance Junior, David William
dc.subject.other.pt_BR.fl_str_mv Papillomavirus Humano
Vacinação
Eventos adversos
topic Papillomavirus Humano
Vacinação
Eventos adversos
Human papillomavirus
Vaccination
Adverse events
dc.subject.en.pt_BR.fl_str_mv Human papillomavirus
Vaccination
Adverse events
description Laboratory of Interdisciplinary Medical Research (LIPMED)
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-04-25T15:56:52Z
dc.date.available.fl_str_mv 2016-04-25T15:56:52Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NICOL, Alcina Frederica et al. HPV vaccines: a controversial issue?. Brazilian Journal of Medical and Biological Research, v. 49, n. 5, p. 1-5, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13963
dc.identifier.issn.none.fl_str_mv 0100-879X
dc.identifier.doi.none.fl_str_mv 10.1590/1414-431X20155060
dc.identifier.eissn.pt_BR.fl_str_mv 1414-431X
identifier_str_mv NICOL, Alcina Frederica et al. HPV vaccines: a controversial issue?. Brazilian Journal of Medical and Biological Research, v. 49, n. 5, p. 1-5, 2016.
0100-879X
10.1590/1414-431X20155060
1414-431X
url https://www.arca.fiocruz.br/handle/icict/13963
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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