Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle

Detalhes bibliográficos
Autor(a) principal: Augusto, Ronaldo de Carvalho
Data de Publicação: 2015
Outros Autores: Friani, Gabriela, Vasconcellos, Mauricio Carvalho de, Rodrigues, Maria de Lurdes de Azevedo, Mello-Silva, Clélia Christina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/14245
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.
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spelling Augusto, Ronaldo de CarvalhoFriani, GabrielaVasconcellos, Mauricio Carvalho deRodrigues, Maria de Lurdes de AzevedoMello-Silva, Clélia Christina2016-05-11T14:20:14Z2016-05-11T14:20:14Z2015AUGUSTO, Ronaldo de Carvalho et al. Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle. Open Journal of Veterinary Medicine, v. 5, p. 127-132, 2015.2165-3356https://www.arca.fiocruz.br/handle/icict/1424510.4236/ojvm.2015.560172165-3364engScientific Research PublishingSchistosoma mansoni: Phytochemical Effect on Aquatic Life Cycleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Universidade Federal Rural do Rio de Janeiro. Departamento de Parasitologia Animal. Curso de Pós-Graduação em Ciências Veterinárias. Seropédica, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Background: Two aspects need to be considered for schistosomiasis control: morbidity and transmission. In this context, many soluble substances have been tested and Euphorbia milii latex is one of the most promising Brazilian molluscicides. Phytochemical studies involving simulation of the applicability of this latex on all aquatic forms of the S. mansoni life cycle are rare in the literature. The aim of this work was to evaluate the effect of E. milii latex on S. mansoni in the egg, miracidium and different developmental stages in Biomphalaria glabrata. Methods: The laboratory study was designed to simulate the different forms of exposure of the life cycle stages of S. mansoni to the LC50 of E. milii latex; we tested the exposition from four situations of S. mansoni contact with the latex and observed the exposure on different snails’ infection stage too. All snails were analyzed weekly for cercarial shedding and reproductive biology. Results: The results showed that contact of S. mansoni eggs and miracidia with the LC50 of E. milii negatively influenced the development of the parasite life cycle in the intermediate host, with consequent reduction of cercarial shedding. The exposure of infected snails affected the reproductive biology and cercarial shedding in all intra-mollusk development stages of S. mansoni, but the reduction was greater in the first, fourth, fifth, sixth, seventh and eighth weeks of infection. The LC50 of E. milii latex had toxic action on eggs and miracidia, and the number of cercariae shed by snails during the study period declined by about 80%. Conclusions: We can conclude that the use of natural biodegradable compounds containing low concentrations of substances already characterized as having eco-toxicological potential can be an important tool to reduce the transmission of Schistosomiasis.SchistosomiasisCercariaeMiracidiaEggsEuphorbia miliiEsquistossomoseEsquistossomose mansoniinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALronaldo_augusto_etal_IOC_2015.pdfronaldo_augusto_etal_IOC_2015.pdfapplication/pdf304764https://www.arca.fiocruz.br/bitstream/icict/14245/2/ronaldo_augusto_etal_IOC_2015.pdfb1fc696dc10b20336beee03d3638aa68MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/14245/3/license.txt5a560609d32a3863062d77ff32785d58MD53TEXTronaldo_augusto_etal_IOC_2015.pdf.txtronaldo_augusto_etal_IOC_2015.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
title Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
spellingShingle Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
Augusto, Ronaldo de Carvalho
Schistosomiasis
Cercariae
Miracidia
Eggs
Euphorbia milii
Esquistossomose
Esquistossomose mansoni
title_short Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
title_full Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
title_fullStr Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
title_full_unstemmed Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
title_sort Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle
author Augusto, Ronaldo de Carvalho
author_facet Augusto, Ronaldo de Carvalho
Friani, Gabriela
Vasconcellos, Mauricio Carvalho de
Rodrigues, Maria de Lurdes de Azevedo
Mello-Silva, Clélia Christina
author_role author
author2 Friani, Gabriela
Vasconcellos, Mauricio Carvalho de
Rodrigues, Maria de Lurdes de Azevedo
Mello-Silva, Clélia Christina
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Augusto, Ronaldo de Carvalho
Friani, Gabriela
Vasconcellos, Mauricio Carvalho de
Rodrigues, Maria de Lurdes de Azevedo
Mello-Silva, Clélia Christina
dc.subject.en.pt_BR.fl_str_mv Schistosomiasis
Cercariae
Miracidia
Eggs
Euphorbia milii
topic Schistosomiasis
Cercariae
Miracidia
Eggs
Euphorbia milii
Esquistossomose
Esquistossomose mansoni
dc.subject.decs.pt_BR.fl_str_mv Esquistossomose
Esquistossomose mansoni
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2016-05-11T14:20:14Z
dc.date.available.fl_str_mv 2016-05-11T14:20:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AUGUSTO, Ronaldo de Carvalho et al. Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle. Open Journal of Veterinary Medicine, v. 5, p. 127-132, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/14245
dc.identifier.issn.none.fl_str_mv 2165-3356
dc.identifier.doi.none.fl_str_mv 10.4236/ojvm.2015.56017
dc.identifier.eissn.none.fl_str_mv 2165-3364
identifier_str_mv AUGUSTO, Ronaldo de Carvalho et al. Schistosoma mansoni: Phytochemical Effect on Aquatic Life Cycle. Open Journal of Veterinary Medicine, v. 5, p. 127-132, 2015.
2165-3356
10.4236/ojvm.2015.56017
2165-3364
url https://www.arca.fiocruz.br/handle/icict/14245
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Scientific Research Publishing
publisher.none.fl_str_mv Scientific Research Publishing
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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