Therapeutic potential of natural products in the treatment of schistosomiasis

Detalhes bibliográficos
Autor(a) principal: Azevedo, Carine Machado
Data de Publicação: 2023
Outros Autores: Meira, Cássio Santana, Silva, Jaqueline Wang da, Moura, Danielle Maria Nascimento, Oliveira, Sheilla Andrade de, Costa, Cícero Jádson da, Santos, Emanuelle de Souza, Soares, Milena Botelho Pereira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60850
Resumo: Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
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spelling Azevedo, Carine MachadoMeira, Cássio SantanaSilva, Jaqueline Wang daMoura, Danielle Maria NascimentoOliveira, Sheilla Andrade deCosta, Cícero Jádson daSantos, Emanuelle de SouzaSoares, Milena Botelho Pereira2023-10-19T15:06:17Z2023-10-19T15:06:17Z2023AZEVEDO, Carine Machado et al. Therapeutic Potential of Natural Products in the Treatment of Schistosomiasis. Molecules, v. 28, n. 19, p. 1-23, 2023.1420-3049https://www.arca.fiocruz.br/handle/icict/6085010.3390/molecules28196807engMDPIEsquistossomoseCompostos naturaisÓleo essencialFerramentas molecularesSchistosomiasisNatural compoundsEssential oilMolecular toolsEsquistossomoseÓleos VoláteisTherapeutic potential of natural products in the treatment of schistosomiasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação em Sistemas Avançados em Saúde (CIMATEC ISI SAS). Salvador, BA, Brasil.Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação em Sistemas Avançados em Saúde (CIMATEC ISI SAS). Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação em Sistemas Avançados em Saúde (CIMATEC ISI SAS). Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação em Sistemas Avançados em Saúde (CIMATEC ISI SAS). Salvador, BA, Brasil.It is estimated that 250 million people worldwide are affected by schistosomiasis. Disease transmission is related to the poor sanitation and hygiene habits that affect residents of impoverished regions in tropical and subtropical countries. The main species responsible for causing disease in humans are Schistosoma Mansoni, S. japonicum, and S. haematobium, each with different geographic distributions. Praziquantel is the drug predominantly used to treat this disease, which offers low effectiveness against immature and juvenile parasite forms. In addition, reports of drug resistance prompt the development of novel therapeutic approaches. Natural products represent an important source of new compounds, especially those obtained from plant sources. This review compiles data from several in vitro and in vivo studies evaluating various compounds and essential oils derived from plants with cercaricidal and molluscicidal activities against both juvenile and adult forms of the parasite. Finally, this review provides an important discussion on recent advances in molecular and computational tools deemed fundamental for more rapid and effective screening of new compounds, allowing for the optimization of time and resources.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60850/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAzevedo, Carine M. - Therapeutic potential.pdfAzevedo, Carine M. - Therapeutic potential.pdfapplication/pdf1859037https://www.arca.fiocruz.br/bitstream/icict/60850/2/Azevedo%2c%20Carine%20M.%20-%20Therapeutic%20potential.pdfe50c38014a5849f9f610d16c3e24f05fMD52icict/608502023-10-19 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dc.title.en_US.fl_str_mv Therapeutic potential of natural products in the treatment of schistosomiasis
title Therapeutic potential of natural products in the treatment of schistosomiasis
spellingShingle Therapeutic potential of natural products in the treatment of schistosomiasis
Azevedo, Carine Machado
Esquistossomose
Compostos naturais
Óleo essencial
Ferramentas moleculares
Schistosomiasis
Natural compounds
Essential oil
Molecular tools
Esquistossomose
Óleos Voláteis
title_short Therapeutic potential of natural products in the treatment of schistosomiasis
title_full Therapeutic potential of natural products in the treatment of schistosomiasis
title_fullStr Therapeutic potential of natural products in the treatment of schistosomiasis
title_full_unstemmed Therapeutic potential of natural products in the treatment of schistosomiasis
title_sort Therapeutic potential of natural products in the treatment of schistosomiasis
author Azevedo, Carine Machado
author_facet Azevedo, Carine Machado
Meira, Cássio Santana
Silva, Jaqueline Wang da
Moura, Danielle Maria Nascimento
Oliveira, Sheilla Andrade de
Costa, Cícero Jádson da
Santos, Emanuelle de Souza
Soares, Milena Botelho Pereira
author_role author
author2 Meira, Cássio Santana
Silva, Jaqueline Wang da
Moura, Danielle Maria Nascimento
Oliveira, Sheilla Andrade de
Costa, Cícero Jádson da
Santos, Emanuelle de Souza
Soares, Milena Botelho Pereira
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Azevedo, Carine Machado
Meira, Cássio Santana
Silva, Jaqueline Wang da
Moura, Danielle Maria Nascimento
Oliveira, Sheilla Andrade de
Costa, Cícero Jádson da
Santos, Emanuelle de Souza
Soares, Milena Botelho Pereira
dc.subject.other.en_US.fl_str_mv Esquistossomose
Compostos naturais
Óleo essencial
Ferramentas moleculares
topic Esquistossomose
Compostos naturais
Óleo essencial
Ferramentas moleculares
Schistosomiasis
Natural compounds
Essential oil
Molecular tools
Esquistossomose
Óleos Voláteis
dc.subject.en.en_US.fl_str_mv Schistosomiasis
Natural compounds
Essential oil
Molecular tools
dc.subject.decs.en_US.fl_str_mv Esquistossomose
Óleos Voláteis
description Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-10-19T15:06:17Z
dc.date.available.fl_str_mv 2023-10-19T15:06:17Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AZEVEDO, Carine Machado et al. Therapeutic Potential of Natural Products in the Treatment of Schistosomiasis. Molecules, v. 28, n. 19, p. 1-23, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60850
dc.identifier.issn.en_US.fl_str_mv 1420-3049
dc.identifier.doi.none.fl_str_mv 10.3390/molecules28196807
identifier_str_mv AZEVEDO, Carine Machado et al. Therapeutic Potential of Natural Products in the Treatment of Schistosomiasis. Molecules, v. 28, n. 19, p. 1-23, 2023.
1420-3049
10.3390/molecules28196807
url https://www.arca.fiocruz.br/handle/icict/60850
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60850/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60850/2/Azevedo%2c%20Carine%20M.%20-%20Therapeutic%20potential.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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