Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil

Detalhes bibliográficos
Autor(a) principal: Oliveira, Jacqueline Ferreira de
Data de Publicação: 2022
Outros Autores: Ávila, Renata Eliane de, Oliveira, Neimy Ramos de, Sampaio, Natália da Cunha Severino, Botelho, Maiara, Gonçalves, Fabíola Araújo, Ferreira Neto, Cirilo José, Milagres, Ana Carolina de Almeida, Gomes, Tatiane Cristina Caldeira, Pereira, Tássia Lopardi, Souza, Renan Pedra de, Molina, Israel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56760
Resumo: Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil
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spelling Oliveira, Jacqueline Ferreira deÁvila, Renata Eliane deOliveira, Neimy Ramos deSampaio, Natália da Cunha SeverinoBotelho, MaiaraGonçalves, Fabíola AraújoFerreira Neto, Cirilo JoséMilagres, Ana Carolina de AlmeidaGomes, Tatiane Cristina CaldeiraPereira, Tássia LopardiSouza, Renan Pedra deMolina, Israel2023-01-30T16:28:48Z2023-01-30T16:28:48Z2022OLIVEIRA, Jacqueline Ferreira de et al. Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil. Int J Infect Dis., v. 122, p. 1044-1051, 2022. doi: 10.1016/j.ijid.2022.07.063.1201-9712https://www.arca.fiocruz.br/handle/icict/56760engElsevierPersistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilInfectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilCritical Care Unit. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilCritical Care Unit. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilEpidemiology Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilEpidemiology Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilInfectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilInfectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilCritical Care. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilInfectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, BrazilIntegrative Biology Laboratory. Genetics, Ecology and Evolution Department. Biological Science Institute. Federal University of Minas Gerais. Belo Horizonte, MG, BrazilInsRené Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, BrazilObjectives: COVID-19 has been associated with long-term consequences to patient wellness and quality of life. Data on post-COVID-19 conditions are scarce in developing countries. This study aimed to investigate long COVID in a cohort of hospitalized patients in Brazil. Methods: Surviving patients discharged from the hospital between July 1, 2020 and March 31, 2021 were assessed between 2 and 12 months after acute onset of COVID-19. The outcomes were the prevalence of persistent symptoms, risk factors associated with long COVID, and quality of life as assessed by the EuroQol 5D-3L questionnaire. Results: Of 439 participants, most (84%) reported at least one long COVID symptom, at a median of 138 days (interquartile range [IQR] 90-201) after disease onset. Fatigue (63.1%), dyspnea (53.7%), arthralgia (56.1%), and depression/anxiety (55.1%) were the most prevalent symptoms. In multivariate analysis, dysgeusia (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.18-3.44, P <0.001) and intensive care unit (ICU) admission (OR 2.6, 95% CI 1.19-6.56, P = 0.03) were independently associated with long COVID. Fifty percent of patients reported a worsened clinical condition and quality of life. Conclusion: Long-term outcomes of SARS-CoV-2 infection in a low- to middle-income country were relevant. Fatigue was the most common persistent symptom. ICU admission was an independent factor associated with long COVID. Dysgeusia could be a potential predictor of long COVID.BrazilCOVID-19DysgeusiaLong COVIDQuality of lifeRisk factorsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALPersistent symptoms, quality of life, and risk factors in long COVID.pdfPersistent symptoms, quality of life, and risk factors in long COVID.pdfapplication/pdf566806https://www.arca.fiocruz.br/bitstream/icict/56760/2/Persistent%20symptoms%2c%20quality%20of%20life%2c%20and%20risk%20factors%20in%20long%20COVID.pdfcdf05b3b6ead7c7e8f4eb03399304c4eMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56760/1/license.txt5a560609d32a3863062d77ff32785d58MD51icict/567602023-01-30 13:28:49.018oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-01-30T16:28:49Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en_US.fl_str_mv Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
title Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
spellingShingle Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
Oliveira, Jacqueline Ferreira de
Brazil
COVID-19
Dysgeusia
Long COVID
Quality of life
Risk factors
title_short Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
title_full Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
title_fullStr Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
title_full_unstemmed Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
title_sort Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
author Oliveira, Jacqueline Ferreira de
author_facet Oliveira, Jacqueline Ferreira de
Ávila, Renata Eliane de
Oliveira, Neimy Ramos de
Sampaio, Natália da Cunha Severino
Botelho, Maiara
Gonçalves, Fabíola Araújo
Ferreira Neto, Cirilo José
Milagres, Ana Carolina de Almeida
Gomes, Tatiane Cristina Caldeira
Pereira, Tássia Lopardi
Souza, Renan Pedra de
Molina, Israel
author_role author
author2 Ávila, Renata Eliane de
Oliveira, Neimy Ramos de
Sampaio, Natália da Cunha Severino
Botelho, Maiara
Gonçalves, Fabíola Araújo
Ferreira Neto, Cirilo José
Milagres, Ana Carolina de Almeida
Gomes, Tatiane Cristina Caldeira
Pereira, Tássia Lopardi
Souza, Renan Pedra de
Molina, Israel
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Jacqueline Ferreira de
Ávila, Renata Eliane de
Oliveira, Neimy Ramos de
Sampaio, Natália da Cunha Severino
Botelho, Maiara
Gonçalves, Fabíola Araújo
Ferreira Neto, Cirilo José
Milagres, Ana Carolina de Almeida
Gomes, Tatiane Cristina Caldeira
Pereira, Tássia Lopardi
Souza, Renan Pedra de
Molina, Israel
dc.subject.en.en_US.fl_str_mv Brazil
COVID-19
Dysgeusia
Long COVID
Quality of life
Risk factors
topic Brazil
COVID-19
Dysgeusia
Long COVID
Quality of life
Risk factors
description Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-01-30T16:28:48Z
dc.date.available.fl_str_mv 2023-01-30T16:28:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, Jacqueline Ferreira de et al. Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil. Int J Infect Dis., v. 122, p. 1044-1051, 2022. doi: 10.1016/j.ijid.2022.07.063.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56760
dc.identifier.issn.en_US.fl_str_mv 1201-9712
identifier_str_mv OLIVEIRA, Jacqueline Ferreira de et al. Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil. Int J Infect Dis., v. 122, p. 1044-1051, 2022. doi: 10.1016/j.ijid.2022.07.063.
1201-9712
url https://www.arca.fiocruz.br/handle/icict/56760
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56760/2/Persistent%20symptoms%2c%20quality%20of%20life%2c%20and%20risk%20factors%20in%20long%20COVID.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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