Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta

Detalhes bibliográficos
Autor(a) principal: Garcia, Aparecida Gomes Pinto
Data de Publicação: 1963
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/3296
Resumo: Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratório de Anatomia Patológica. Rio de Janeiro, RJ, Brasil.
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spelling Garcia, Aparecida Gomes Pinto2011-11-01T16:37:04Z2011-11-01T16:37:04Z1963GARCIA, Aparecida Gomes Pinto. Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta. Pediatrics, Evanston, v. 32, n. 5, p. 895-901, nov. 1963.0031-4005https://www.arca.fiocruz.br/handle/icict/3296engFetal infection in chickenpox and alastrim, with histopathologic study of the placentainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratório de Anatomia Patológica. Rio de Janeiro, RJ, Brasil.Four cases of congenital viral disease are presented. Two cases were of chickenpox (a 2-day old infant and a macerated abortion) and two were of so-called alastrim, which is probably mitigated smallpox (macerated abortions). In all of them one special type of lesion was present: focal, irregularly sized areas of necrosis, with calcium deposits in the central part, sharply demarcated from the surrounding normal parenchyma and accompanied by slight or absent peripheral inflammatory reaction. In Case 1 (an infant who lived 2 days) such lesions were disseminated to all the viscera, especially the brain; the microscopic aspect was like that of congenital toxoplasmosis, and the microscopic examination revealed an essentially necrotizing inflammatory process with extensive calcification and glial reaction. The placenta, examined in two cases of alastrim and one of chickenpox, exhibited similar lesions both on gross and microscopic examination. On the surface and on the cut section there were numerous minute, irregularly spread yellowish areas. The histology showed the presence of tuberculoid-type granulomatous lesions in the villi and extensive areas of necrosis, the intervillous space being occupied by necrotic material and cellular debris. In one of the cases of alastrim (Case 3), there was predominance of the granulomatous lesions; in the other (Case 4), necrosis predominated; in Case 2, of chickenpox, beside the granulomatous lesions, there was extensive necrosis. In the decidual cells there were characteristic inclusions of both the virus diseases. Such placental lesions apparently have not previously been described.VaricelaDoenças FetaisComplicações Infecciosas na GravidezGranulomaRimPatologiaPlacentaRecém-nascidoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1648https://www.arca.fiocruz.br/bitstream/icict/3296/1/license.txte095249ac7cacefbfe39684dfe45e706MD51ORIGINAL1963 - Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta.pdfapplication/pdf1348884https://www.arca.fiocruz.br/bitstream/icict/3296/2/1963%20-%20%20Fetal%20infection%20in%20chickenpox%20and%20alastrim%2c%20with%20histopathologic%20study%20of%20the%20placenta.pdf8d1aba4834df7cf1a00210caeb1624f8MD52TEXT1963 - Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta.pdf.txt1963 - Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta.pdf.txtExtracted texttext/plain26328https://www.arca.fiocruz.br/bitstream/icict/3296/5/1963%20-%20%20Fetal%20infection%20in%20chickenpox%20and%20alastrim%2c%20with%20histopathologic%20study%20of%20the%20placenta.pdf.txt43c93a699908da582dbacfcd88cd5ddcMD55THUMBNAIL1963 - Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta.pdf.jpg1963 - Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta.pdf.jpgGenerated Thumbnailimage/jpeg1612https://www.arca.fiocruz.br/bitstream/icict/3296/4/1963%20-%20%20Fetal%20infection%20in%20chickenpox%20and%20alastrim%2c%20with%20histopathologic%20study%20of%20the%20placenta.pdf.jpgdc9decceeac631e0e725514ff4e19dc0MD54icict/32962018-08-29 21:32:05.593oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-08-30T00:32:05Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
title Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
spellingShingle Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
Garcia, Aparecida Gomes Pinto
Varicela
Doenças Fetais
Complicações Infecciosas na Gravidez
Granuloma
Rim
Patologia
Placenta
Recém-nascido
title_short Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
title_full Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
title_fullStr Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
title_full_unstemmed Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
title_sort Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta
author Garcia, Aparecida Gomes Pinto
author_facet Garcia, Aparecida Gomes Pinto
author_role author
dc.contributor.author.fl_str_mv Garcia, Aparecida Gomes Pinto
dc.subject.decs.pt_BR.fl_str_mv Varicela
Doenças Fetais
Complicações Infecciosas na Gravidez
Granuloma
Rim
Patologia
Placenta
Recém-nascido
topic Varicela
Doenças Fetais
Complicações Infecciosas na Gravidez
Granuloma
Rim
Patologia
Placenta
Recém-nascido
description Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratório de Anatomia Patológica. Rio de Janeiro, RJ, Brasil.
publishDate 1963
dc.date.issued.fl_str_mv 1963
dc.date.accessioned.fl_str_mv 2011-11-01T16:37:04Z
dc.date.available.fl_str_mv 2011-11-01T16:37:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GARCIA, Aparecida Gomes Pinto. Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta. Pediatrics, Evanston, v. 32, n. 5, p. 895-901, nov. 1963.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/3296
dc.identifier.issn.pt_BR.fl_str_mv 0031-4005
identifier_str_mv GARCIA, Aparecida Gomes Pinto. Fetal infection in chickenpox and alastrim, with histopathologic study of the placenta. Pediatrics, Evanston, v. 32, n. 5, p. 895-901, nov. 1963.
0031-4005
url https://www.arca.fiocruz.br/handle/icict/3296
dc.language.iso.fl_str_mv eng
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collection Repositório Institucional da FIOCRUZ (ARCA)
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