Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)

Sousa Jr., Ivanildo P.; Oliveira, Maria de Lourdes Aguiar; Burlandy, Fernanda M.; Machado, Raiana S.; Oliveira, Silas S.; Tavares, Fernando N.; Gomes Neto, Francisco; Costa, Eliane V. da; Silva, Edson E. da

Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)

Detalhes bibliográficos
Autor(a) principal:	Sousa Jr., Ivanildo P.
Data de Publicação:	2020
Outros Autores:	Oliveira, Maria de Lourdes Aguiar, Burlandy, Fernanda M., Machado, Raiana S., Oliveira, Silas S., Tavares, Fernando N., Gomes Neto, Francisco, Costa, Eliane V. da, Silva, Edson E. da
Tipo de documento:	Artigo
Idioma:	eng
Título da fonte:	Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo:	https://www.arca.fiocruz.br/handle/icict/44713
Resumo:	Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.

Metadados do item

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spelling	Sousa Jr., Ivanildo P.Oliveira, Maria de Lourdes AguiarBurlandy, Fernanda M.Machado, Raiana S.Oliveira, Silas S.Tavares, Fernando N.Gomes Neto, FranciscoCosta, Eliane V. daSilva, Edson E. da2020-12-03T13:56:44Z2020-12-03T13:56:44Z2020SOUSA JR., Ivanildo P. et al. Molecular characterization and epidemiological aspects of non-polio enteroviruses isolated from acute flaccid paralysis in Brasil: a historical series (2005-2017). Emerging Microbes & Infections, v. 9, p. 2536-2546, Dec. 2020.2222-1751https://www.arca.fiocruz.br/handle/icict/4471310.1080/22221751.2020.1850181engTaylor & FrancisEnterovírus não-poliomieliteParalisia flácido agudaEnterovirusEpidemiologia molecularVigilância da poliomieliteNon-polio enterovirusAcute flaccid paralysisEnterovirusMolecular epidemiologyPoliomyelitis surveillanceMolecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Instituto Evandro Chagas. Seção de Virologia. Laboratório de Referência Regional em Enteroviroses. Ananindeua, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.Due to the advanced stage of polio eradication, the possible role of non-polio enteroviruses (NPEVs) associated to acute flaccid paralysis (AFP) cases has been highlighted. In this study, we described epidemiological aspects of NPEVs infections associated to AFP and explore the viral genetic diversity, information still scarce in Brazil. From 2005 to 2017, 6707 stool samples were collected in the scope of the Brazilian Poliomyelitis Surveillance Program. NPEVs were isolated in 359 samples (5.3%) and 341 (94.9%) were genotyped. About 46 different NPEV types were identified with the following detection pattern EV-B > EV-A > EV-C. The major EV-types were CVA2, CV4, EV-A71, CVB3, CVB5, E6, E7, E11, CVA13 and EV-C99, which corresponds to 51.6% of the total. Uncommon types, such as CVA12, EV-90 and CVA11, were also identified. Different E6 genogroups were observed, prevailing the GenIII, despite periods of co-circulation, and replacement of genogroups along time. CVA2 sequences were classified as genotype C and data suggested its dispersion in South-American countries. CVA13 viruses belonged to cluster B and Venezuelan viruses composed a new putative cluster. This study provides extensive information on enterovirus diversity associated with AFP, reinforcing the need of tailoring current surveillance strategies to timely monitor emergence/re-emergence of NPEVs.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/44713/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALEdsonESilva_IvanildoSousa_etal_IOC_2020.pdfEdsonESilva_IvanildoSousa_etal_IOC_2020.pdfapplication/pdf1581437https://www.arca.fiocruz.br/bitstream/icict/44713/2/EdsonESilva_IvanildoSousa_etal_IOC_2020.pdf50c158d3e7f97063cbc4ccbe6e5fea7aMD52TEXTEdsonESilva_IvanildoSousa_etal_IOC_2020.pdf.txtEdsonESilva_IvanildoSousa_etal_IOC_2020.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
title	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
spellingShingle	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017) Sousa Jr., Ivanildo P. Enterovírus não-poliomielite Paralisia flácido aguda Enterovirus Epidemiologia molecular Vigilância da poliomielite Non-polio enterovirus Acute flaccid paralysis Enterovirus Molecular epidemiology Poliomyelitis surveillance
title_short	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
title_full	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
title_fullStr	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
title_full_unstemmed	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
title_sort	Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)
author	Sousa Jr., Ivanildo P.
author_facet	Sousa Jr., Ivanildo P. Oliveira, Maria de Lourdes Aguiar Burlandy, Fernanda M. Machado, Raiana S. Oliveira, Silas S. Tavares, Fernando N. Gomes Neto, Francisco Costa, Eliane V. da Silva, Edson E. da
author_role	author
author2	Oliveira, Maria de Lourdes Aguiar Burlandy, Fernanda M. Machado, Raiana S. Oliveira, Silas S. Tavares, Fernando N. Gomes Neto, Francisco Costa, Eliane V. da Silva, Edson E. da
author2_role	author author author author author author author author
dc.contributor.author.fl_str_mv	Sousa Jr., Ivanildo P. Oliveira, Maria de Lourdes Aguiar Burlandy, Fernanda M. Machado, Raiana S. Oliveira, Silas S. Tavares, Fernando N. Gomes Neto, Francisco Costa, Eliane V. da Silva, Edson E. da
dc.subject.other.pt_BR.fl_str_mv	Enterovírus não-poliomielite Paralisia flácido aguda Enterovirus Epidemiologia molecular Vigilância da poliomielite
topic	Enterovírus não-poliomielite Paralisia flácido aguda Enterovirus Epidemiologia molecular Vigilância da poliomielite Non-polio enterovirus Acute flaccid paralysis Enterovirus Molecular epidemiology Poliomyelitis surveillance
dc.subject.en.pt_BR.fl_str_mv	Non-polio enterovirus Acute flaccid paralysis Enterovirus Molecular epidemiology Poliomyelitis surveillance
description	Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil.
publishDate	2020
dc.date.accessioned.fl_str_mv	2020-12-03T13:56:44Z
dc.date.available.fl_str_mv	2020-12-03T13:56:44Z
dc.date.issued.fl_str_mv	2020
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv	info:eu-repo/semantics/article
format	article
status_str	publishedVersion
dc.identifier.citation.fl_str_mv	SOUSA JR., Ivanildo P. et al. Molecular characterization and epidemiological aspects of non-polio enteroviruses isolated from acute flaccid paralysis in Brasil: a historical series (2005-2017). Emerging Microbes & Infections, v. 9, p. 2536-2546, Dec. 2020.
dc.identifier.uri.fl_str_mv	https://www.arca.fiocruz.br/handle/icict/44713
dc.identifier.issn.pt_BR.fl_str_mv	2222-1751
dc.identifier.doi.none.fl_str_mv	10.1080/22221751.2020.1850181
identifier_str_mv	SOUSA JR., Ivanildo P. et al. Molecular characterization and epidemiological aspects of non-polio enteroviruses isolated from acute flaccid paralysis in Brasil: a historical series (2005-2017). Emerging Microbes & Infections, v. 9, p. 2536-2546, Dec. 2020. 2222-1751 10.1080/22221751.2020.1850181
url	https://www.arca.fiocruz.br/handle/icict/44713
dc.language.iso.fl_str_mv	eng
language	eng
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	Taylor & Francis
publisher.none.fl_str_mv	Taylor & Francis
dc.source.none.fl_str_mv	reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ
instname_str	Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str	FIOCRUZ
institution	FIOCRUZ
reponame_str	Repositório Institucional da FIOCRUZ (ARCA)
collection	Repositório Institucional da FIOCRUZ (ARCA)
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repository.name.fl_str_mv	Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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Molecular characterization and epidemiological aspects of non-polioenteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005-2017)

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