Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial

Detalhes bibliográficos
Autor(a) principal: O'Connor, Jemma
Data de Publicação: 2017
Outros Autores: Vjecha, Michael J, Phillips, Andrew N, Angus, Brian, Cooper, David, Grinsztejn, Beatriz, Lopardo, Gustavo, Das, Satyajit, Wood, Robin, Wilkin, Aimee, Klinker, Hartwig, Kantipong, Pacharee, Klingman, Karin L, Jilich, David, Herieka, Elbushra, Denning, Eileen, Abubakar, Ibrahim, Gordin, Fred, Lundgren, Jens D
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25427
Resumo: University College London. Research Department of Infection and Population Health, London, UK.
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spelling O'Connor, JemmaVjecha, Michael JPhillips, Andrew NAngus, BrianCooper, DavidGrinsztejn, BeatrizLopardo, GustavoDas, SatyajitWood, RobinWilkin, AimeeKlinker, HartwigKantipong, PachareeKlingman, Karin LJilich, DavidHerieka, ElbushraDenning, EileenAbubakar, IbrahimGordin, FredLundgren, Jens D2018-03-20T15:30:59Z2018-03-20T15:30:59Z2017O'Connor, J. et. al. Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial. Lancet HIV. v.4, n.3, mar. 2017, p. 105-112.2405-4704https://www.arca.fiocruz.br/handle/icict/2542710.1016/S2352-3018(16)30216-8porElsivierAntígenos CD4Terapia Antirretroviral de Alta AtividadeInfecções BacterianasAntiretroviral Therapy, Highly ActiveBacterial InfectionsAntígenos CD4Terapia Antirretroviral de Alta AtividadeInfecções BacterianasEffect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity College London. Research Department of Infection and Population Health, London, UK.Veterans Affairs Medical Center, Washington, DC, USA.Research Department of Infection and Population Health, University College London, London, UK.Oxford Centre for Clinical Tropical Medicine, Nuffield Department of Medicine, Oxford University, Oxford, UK.The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.Instituto Nacional de Infectologia Evandro Chagas. STD and AIDS Clinical Research Laboratory, Rio de Janeiro, Brazil.Fundación Centro de Estudios Infectológicos, Buenos Aires, Argentina.HIV and GU Medicine, Coventry and Warwickshire Partnership Trust, University of Warwick, Coventry, UKDesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa.Section on Infectious Diseases, Wake Forest University School of Medicine, Winston-Salem, NC, USA.University of Würzburg Medical Center, Department of Internal Medicine II, Würzburg, GermanyChaingrai Prachanukroh Hospital, Chaingrai, ThailandDivision of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USADepartment of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University and Na Bulovce Hospital, Prague, Czech RepublicRoyal Bournemouth Hospital, Bournemouth, UK.Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA.Institute for Global Health, University College London, London, UKVeterans Affairs Medical Center, Washington, DC, USA; The George Washington University, Washington, DC, USA.Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.The effects of antiretroviral therapy on risk of severe bacterial infections in people with high CD4 cell counts have not been well described. In this study, we aimed to quantify the effects of immediate versus deferred ART on the risk of severe bacterial infection in people with high CD4 cell counts in a preplanned analysis of the START trial.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/25427/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALEffect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections.pdfEffect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections.pdfapplication/pdf603934https://www.arca.fiocruz.br/bitstream/icict/25427/2/Effect%20of%20immediate%20initiation%20of%20antiretroviral%20therapy%20on%20risk%20of%20severe%20bacterial%20infections.pdf89950b4155dbb3a30a581b961e0c931aMD52TEXTEffect of immediate initiation of antiretroviral therapy 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dc.title.pt_BR.fl_str_mv Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
title Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
spellingShingle Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
O'Connor, Jemma
Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
Antiretroviral Therapy, Highly Active
Bacterial Infections
Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
title_short Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
title_full Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
title_fullStr Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
title_full_unstemmed Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
title_sort Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial
author O'Connor, Jemma
author_facet O'Connor, Jemma
Vjecha, Michael J
Phillips, Andrew N
Angus, Brian
Cooper, David
Grinsztejn, Beatriz
Lopardo, Gustavo
Das, Satyajit
Wood, Robin
Wilkin, Aimee
Klinker, Hartwig
Kantipong, Pacharee
Klingman, Karin L
Jilich, David
Herieka, Elbushra
Denning, Eileen
Abubakar, Ibrahim
Gordin, Fred
Lundgren, Jens D
author_role author
author2 Vjecha, Michael J
Phillips, Andrew N
Angus, Brian
Cooper, David
Grinsztejn, Beatriz
Lopardo, Gustavo
Das, Satyajit
Wood, Robin
Wilkin, Aimee
Klinker, Hartwig
Kantipong, Pacharee
Klingman, Karin L
Jilich, David
Herieka, Elbushra
Denning, Eileen
Abubakar, Ibrahim
Gordin, Fred
Lundgren, Jens D
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv O'Connor, Jemma
Vjecha, Michael J
Phillips, Andrew N
Angus, Brian
Cooper, David
Grinsztejn, Beatriz
Lopardo, Gustavo
Das, Satyajit
Wood, Robin
Wilkin, Aimee
Klinker, Hartwig
Kantipong, Pacharee
Klingman, Karin L
Jilich, David
Herieka, Elbushra
Denning, Eileen
Abubakar, Ibrahim
Gordin, Fred
Lundgren, Jens D
dc.subject.other.pt_BR.fl_str_mv Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
topic Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
Antiretroviral Therapy, Highly Active
Bacterial Infections
Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
dc.subject.en.pt_BR.fl_str_mv Antiretroviral Therapy, Highly Active
Bacterial Infections
dc.subject.decs.pt_BR.fl_str_mv Antígenos CD4
Terapia Antirretroviral de Alta Atividade
Infecções Bacterianas
description University College London. Research Department of Infection and Population Health, London, UK.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-03-20T15:30:59Z
dc.date.available.fl_str_mv 2018-03-20T15:30:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv O'Connor, J. et. al. Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial. Lancet HIV. v.4, n.3, mar. 2017, p. 105-112.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25427
dc.identifier.issn.pt_BR.fl_str_mv 2405-4704
dc.identifier.doi.none.fl_str_mv 10.1016/S2352-3018(16)30216-8
identifier_str_mv O'Connor, J. et. al. Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial. Lancet HIV. v.4, n.3, mar. 2017, p. 105-112.
2405-4704
10.1016/S2352-3018(16)30216-8
url https://www.arca.fiocruz.br/handle/icict/25427
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