Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/48763 |
Resumo: | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil. |
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Slavov, Svetoslav NanevGiovanetti, MartaBezerra, Rafael dos SantosFonseca, VagnerSantos, Elaine VieiraRodrigues, Evandra StrazzaAdelino, Talita Émile RibeiroXavier, JoilsonBorges, Josiane SerranoEvaristo, MarianeLima, Mauricio TeixeiraPereira, Glauco de CarvalhoYamamoto, Aparecida YulieClé, Diego VillaCalado, Rodrigo TocantinsCovas, Dimas TadeuAlcantara, Luiz Carlos JuniorKashima, Simone2021-08-26T14:03:34Z2021-08-26T14:03:34Z2021SLAVOV, Svetoslav Nanev et al. Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil . Infection, Genetics and Evolution, v. 93, 104976, 4 p, June 021.1567-1348https://www.arca.fiocruz.br/handle/icict/4876310.1016/j.meegid.2021.104976engElsevierSARS-CoV-2COVID-19Variantes de preocupaçãoVOCGenoma inteiroP.1SARS-CoV-2COVID-19Variants of concernVOCP.1Whole genomePhylogenyMolecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil / KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), College of Health Sciences, University of KwaZuluNatal. Durban 4001, South Africa.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Universidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil / Fundação Ezequiel Dias. Laboratório Central de Saúde Pùblica. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, BrasilUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.Fundação Ezequiel Dias. Laboratório Central de Saúde Pùblica. Belo Horizonte, MG, BrasilFundação Ezequiel Dias. Laboratório Central de Saúde Pùblica. Belo Horizonte, MG, BrasilUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Imagens Médicas, Hematologia e Oncologia. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Imagens Médicas, Hematologia e Oncologia. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil / Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Imagens Médicas, Hematologia e Oncologia. Ribeirão Preto, SP, Brasil..Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil / Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Imagens Médicas, Hematologia e Oncologia. Ribeirão Preto, SP, Brasil..Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil.The Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of an unprecedented worldwide pandemic. Brazil demonstrates one of the highest numbers of confirmed SARS-CoV-2 cases, and Sao ˜ Paulo State is the epicenter of the pandemics in the country. Nevertheless, little is known about the SARS-CoV-2 circulation in other cities in the State than S˜ ao Paulo city. The objective of this study was to analyze phyloge netically SARS-CoV-2 strains circulating in city of Ribeir˜ ao Preto at the beginning of the pandemic and during the actual second wave. Twenty-nine nasopharyngeal SARS-CoV-2 RNA positive samples were sequenced by nano pore technology (18 obtained at the initial period of the pandemic and 11 during the second wave) and analyzed them phylogenetically. The performed analysis demonstrated that the majority of the strains obtained in the initial period of the pandemic in Ribeir˜ ao Preto belonged mainly to the B1.1.33 lineage (61.1%), but B.1.1 (27.8%) and B.1.1.28 (11.1%) lineages were also identified. In contrast, the second wave strains were composed exclusively by the Brazilian variant of concern (VOC) P.1 (91%) and P.2 (9%) lineages. The obtained phyloge netic results were suggestive of successive SARS-CoV-2 lineage substitution in this Brazilian region by the P.1 VOC. The performed study examines the SARS-CoV-2 genotypes in Ribeir˜ ao Preto city via genomic surveillance data. The obtained findings can contribute for continuous long-term genomic surveillance of SARS-CoV-2 due to the accelerated dynamics of viral lineage substitution, predict further waves and examine lineage behavior during SARS-CoV-2 vaccination.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48763/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLuizCAlcantara_MartaGiovanetti_JoilsonXavier__etal_IOC_2021.pdfLuizCAlcantara_MartaGiovanetti_JoilsonXavier__etal_IOC_2021.pdfapplication/pdf1169774https://www.arca.fiocruz.br/bitstream/icict/48763/2/LuizCAlcantara_MartaGiovanetti_JoilsonXavier__etal_IOC_2021.pdfce213b1d96adb895dccf4e0e3dcccd27MD52TEXTLuizCAlcantara_MartaGiovanetti_JoilsonXavier__etal_IOC_2021.pdf.txtLuizCAlcantara_MartaGiovanetti_JoilsonXavier__etal_IOC_2021.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| title |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| spellingShingle |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil Slavov, Svetoslav Nanev SARS-CoV-2 COVID-19 Variantes de preocupação VOC Genoma inteiro P.1 SARS-CoV-2 COVID-19 Variants of concern VOC P.1 Whole genome Phylogeny |
| title_short |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| title_full |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| title_fullStr |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| title_full_unstemmed |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| title_sort |
Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil |
| author |
Slavov, Svetoslav Nanev |
| author_facet |
Slavov, Svetoslav Nanev Giovanetti, Marta Bezerra, Rafael dos Santos Fonseca, Vagner Santos, Elaine Vieira Rodrigues, Evandra Strazza Adelino, Talita Émile Ribeiro Xavier, Joilson Borges, Josiane Serrano Evaristo, Mariane Lima, Mauricio Teixeira Pereira, Glauco de Carvalho Yamamoto, Aparecida Yulie Clé, Diego Villa Calado, Rodrigo Tocantins Covas, Dimas Tadeu Alcantara, Luiz Carlos Junior Kashima, Simone |
| author_role |
author |
| author2 |
Giovanetti, Marta Bezerra, Rafael dos Santos Fonseca, Vagner Santos, Elaine Vieira Rodrigues, Evandra Strazza Adelino, Talita Émile Ribeiro Xavier, Joilson Borges, Josiane Serrano Evaristo, Mariane Lima, Mauricio Teixeira Pereira, Glauco de Carvalho Yamamoto, Aparecida Yulie Clé, Diego Villa Calado, Rodrigo Tocantins Covas, Dimas Tadeu Alcantara, Luiz Carlos Junior Kashima, Simone |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Slavov, Svetoslav Nanev Giovanetti, Marta Bezerra, Rafael dos Santos Fonseca, Vagner Santos, Elaine Vieira Rodrigues, Evandra Strazza Adelino, Talita Émile Ribeiro Xavier, Joilson Borges, Josiane Serrano Evaristo, Mariane Lima, Mauricio Teixeira Pereira, Glauco de Carvalho Yamamoto, Aparecida Yulie Clé, Diego Villa Calado, Rodrigo Tocantins Covas, Dimas Tadeu Alcantara, Luiz Carlos Junior Kashima, Simone |
| dc.subject.other.pt_BR.fl_str_mv |
SARS-CoV-2 COVID-19 Variantes de preocupação VOC Genoma inteiro P.1 |
| topic |
SARS-CoV-2 COVID-19 Variantes de preocupação VOC Genoma inteiro P.1 SARS-CoV-2 COVID-19 Variants of concern VOC P.1 Whole genome Phylogeny |
| dc.subject.en.pt_BR.fl_str_mv |
SARS-CoV-2 COVID-19 Variants of concern VOC P.1 Whole genome Phylogeny |
| description |
Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brasil. |
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2021 |
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2021-08-26T14:03:34Z |
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2021-08-26T14:03:34Z |
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2021 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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SLAVOV, Svetoslav Nanev et al. Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil . Infection, Genetics and Evolution, v. 93, 104976, 4 p, June 021. |
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https://www.arca.fiocruz.br/handle/icict/48763 |
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1567-1348 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.meegid.2021.104976 |
| identifier_str_mv |
SLAVOV, Svetoslav Nanev et al. Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil . Infection, Genetics and Evolution, v. 93, 104976, 4 p, June 021. 1567-1348 10.1016/j.meegid.2021.104976 |
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eng |
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openAccess |
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Elsevier |
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Elsevier |
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