Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.

Detalhes bibliográficos
Autor(a) principal: Camandaroba, Edson Luiz Paes
Data de Publicação: 2002
Outros Autores: Lima, Clarissa M. Pinheiro, Andrade, Sonia Gumes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/4590
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Camandaroba, Edson Luiz PaesLima, Clarissa M. PinheiroAndrade, Sonia Gumes2012-09-05T20:48:03Z2012-09-05T20:48:03Z2002CAMANDAROBA, E.L.; LIMA, C.M.P.; ANDRADE, S.G.Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection. Revista do Instituto de Medicina Tropical de Sao Paulo, v. 44, n. 2, p. 97-103, mar.-apr. 2002.0036-4665https://www.arca.fiocruz.br/handle/icict/4590engTrypanosoma cruziOral transmissionExperimental intragastric infection; T.cruzi strains infectivityBiodemes.Doença de Chagas/transmissãoTrypanosoma cruzi/patogenicidadeAnimaisDoença de Chagas/parasitologiaDoença de Chagas/patologiaModelos Animais de DoençasCamundongosFatores de TempoOral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilOral transmission of Trypanosoma cruzi has been suspected when epidemic episodes of acute infection were observed in areas devoid of domiciled insect vectors. Considering that the distribution of T. cruzi biodemes differs in sylvatic and domestic cycles, results of studies on biodemes can be of interest regarding oral transmission. The infectivity of T. cruzi strains of different biodemes was tested in mice subjected to infection by the digestive route (gavage). Swiss mice were infected either with the Peruvian strain (Biodeme Type I, Z2b) or the Colombian strain (Biodeme Type III, Z1, or T. cruzi I); for control, intraperitoneal inoculation was performed in a group of mice. The Colombian strain revealed a similar high infectivity and pathogenicity when either route of infection was used. However, the Peruvian strain showed contrasting levels of infectivity and pathogenicity, being high by intraperitoneal inoculation and low when the gastric route was used. The higher infectivity of the Colombian strain (Biodeme Type III) by gastric inoculation is in keeping with its role in the epidemic episodes of acute Chagas disease registered in the literature, since strains belonging to Biodeme III are most often found in sylvatic hosts.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALCamandaroba EL Oral transmission of Chagas ....pdfCamandaroba EL Oral transmission of Chagas ....pdfapplication/pdf264731https://www.arca.fiocruz.br/bitstream/icict/4590/1/Camandaroba%20EL%20Oral%20transmission%20of%20Chagas%20....pdfb78bde151c91cab060aef6f71e860d0eMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/4590/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTCamandaroba EL Oral transmission of Chagas ....pdf.txtCamandaroba EL Oral transmission of Chagas ....pdf.txtExtracted texttext/plain27372https://www.arca.fiocruz.br/bitstream/icict/4590/5/Camandaroba%20EL%20Oral%20transmission%20of%20Chagas%20....pdf.txta40b3676b0221322afcf65924253a42cMD55THUMBNAILCamandaroba EL Oral transmission of Chagas ....pdf.jpgCamandaroba EL Oral transmission of Chagas ....pdf.jpgGenerated Thumbnailimage/jpeg1977https://www.arca.fiocruz.br/bitstream/icict/4590/4/Camandaroba%20EL%20Oral%20transmission%20of%20Chagas%20....pdf.jpga35aab66610f92483df75ff806b219d4MD54icict/45902023-03-15 14:34:03.113oai:www.arca.fiocruz.br:icict/4590TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGFzc2luYXIgZSBlbnRyZWdhciBlc3RhIGxpY2Vuw6dhLCBvL2EgU3IuL1NyYS4gKGF1dG9yIG91IGRldGVudG9yIGRvcyBkaXJlaXRvcyBkbyBhdXRvcik6CgpBbyBjb25jb3JkYXIgZSBhY2VpdGFyIGVzdGEgbGljZW7Dp2Egdm9jw6ogKGF1dG9yIG91IGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyk6CgphKSBEZWNsYXJhIHF1ZSBjb25oZWNlIGEgcG9sw610aWNhIGRlIGNvcHlyaWdodCBkYSBlZGl0b3JhIGRvIHNldSBkb2N1bWVudG8uCgpiKSBEZWNsYXJhIHF1ZSBjb25oZWNlIGUgYWNlaXRhIGFzIERpcmV0cml6ZXMgcGFyYSBvIFJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIEZ1bmRhw6fDo28gT3N3YWxkbyBDcnV6IChGSU9DUlVaKS4KCmMpIENvbmNlZGUgw6AgRklPQ1JVWiBvIGRpcmVpdG8gbsOjby1leGNsdXNpdm8gZGUgYXJxdWl2YXIsIHJlcHJvZHV6aXIsIGNvbnZlcnRlciAoY29tbyBkZWZpbmlkbyBhIHNlZ3VpciksIGNvbXVuaWNhcgogCmUvb3UgZGlzdHJpYnVpciBubyBSZXBvc2l0w7NyaW8gZGEgRklPQ1JVWiwgbyBkb2N1bWVudG8gZW50cmVndWUgKGluY2x1aW5kbyBvIHJlc3Vtby9hYnN0cmFjdCkgZW0gZm9ybWF0byBkaWdpdGFsIG91IAoKcG9yIHF1YWxxdWVyIG91dHJvIG1laW8uCgpkKSBEZWNsYXJhIHF1ZSBhdXRvcml6YSBhIEZJT0NSVVogYSBhcnF1aXZhciBtYWlzIGRlIHVtYSBjw7NwaWEgZGVzdGUgZG9jdW1lbnRvIGUgY29udmVydMOqLWxvLCBzZW0gYWx0ZXJhciBvIHNldSBjb250ZcO6ZG8sIAoKcGFyYSBxdWFscXVlciBmb3JtYXRvIGRlIGFycXVpdm8sIG1laW8gb3Ugc3Vwb3J0ZSwgcGFyYSBlZmVpdG9zIGRlIHNlZ3VyYW7Dp2EsIHByZXNlcnZhw6fDo28gKGJhY2t1cCkgZSBhY2Vzc28uCgplKSBEZWNsYXJhIHF1ZSBvIGRvY3VtZW50byBzdWJtZXRpZG8gw6kgbyBzZXUgdHJhYmFsaG8gb3JpZ2luYWwsIGUgcXVlIGRldMOpbSBvIGRpcmVpdG8gZGUgY29uY2VkZXIgYSB0ZXJjZWlyb3Mgb3MgZGlyZWl0b3MgCgpjb250aWRvcyBuZXN0YSBsaWNlbsOnYS4gRGVjbGFyYSB0YW1iw6ltIHF1ZSBhIGVudHJlZ2EgZG8gZG9jdW1lbnRvIG7Do28gaW5mcmluZ2Ugb3MgZGlyZWl0b3MgZGUgcXVhbHF1ZXIgb3V0cmEgcGVzc29hIG91IGVudGlkYWRlLgoKZikgRGVjbGFyYSBxdWUsIG5vIGNhc28gZG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyBjb250ZXIgbWF0ZXJpYWwgZG8gcXVhbCBuw6NvIGRldMOpbSBvcyBkaXJlaXRvcyBkZSBhdXRvciwgb2J0ZXZlIGEgYXV0b3JpemHDp8OjbyAKCmlycmVzdHJpdGEgZG8gcmVzcGVjdGl2byBkZXRlbnRvciBkZXNzZXMgZGlyZWl0b3MsIHBhcmEgY2VkZXIgYSBGSU9DUlVaIG9zIGRpcmVpdG9zIHJlcXVlcmlkb3MgcG9yIGVzdGEgTGljZW7Dp2EgZSBhdXRvcml6YXIgYSAKCnV0aWxpesOhLWxvcyBsZWdhbG1lbnRlLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGVzc2UgbWF0ZXJpYWwgY3Vqb3MgZGlyZWl0b3Mgc8OjbyBkZSB0ZXJjZWlyb3MgZXN0w6EgY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyAKCm5vIHRleHRvIG91IGNvbnRlw7pkbyBkbyBkb2N1bWVudG8gZW50cmVndWUuCgpnKSBTRSBPIERPQ1VNRU5UTyBFTlRSRUdVRSDDiSBCQVNFQURPIEVNIFRSQUJBTEhPIEZJTkFOQ0lBRE8gT1UgQVBPSUFETyBQT1IgT1VUUkEgSU5TVElUVUnDh8ODTyBRVUUgTsODTyBBIEZJT0NSVVosIERFQ0xBUkEgUVVFIENVTVBSSVUgCgpRVUFJU1FVRVIgT0JSSUdBw4fDlUVTIEVYSUdJREFTIFBFTE8gUkVTUEVDVElWTyBDT05UUkFUTyBPVSBBQ09SRE8uIEEgRklPQ1JVWiBpZGVudGlmaWNhcsOhIGNsYXJhbWVudGUgbyhzKSBub21lKHMpIGRvKHMpIGF1dG9yKGVzKSBkb3MgCgpkaXJlaXRvcyBkbyBkb2N1bWVudG8gZW50cmVndWUgZSBuw6NvIGZhcsOhIHF1YWxxdWVyIGFsdGVyYcOnw6NvLCBwYXJhIGFsw6ltIGRvIHByZXZpc3RvIG5hIGFsw61uZWEgYykuCg==Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:03Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
title Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
spellingShingle Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
Camandaroba, Edson Luiz Paes
Trypanosoma cruzi
Oral transmission
Experimental intragastric infection; T.cruzi strains infectivity
Biodemes.
Doença de Chagas/transmissão
Trypanosoma cruzi/patogenicidade
Animais
Doença de Chagas/parasitologia
Doença de Chagas/patologia
Modelos Animais de Doenças
Camundongos
Fatores de Tempo
title_short Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
title_full Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
title_fullStr Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
title_full_unstemmed Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
title_sort Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection.
author Camandaroba, Edson Luiz Paes
author_facet Camandaroba, Edson Luiz Paes
Lima, Clarissa M. Pinheiro
Andrade, Sonia Gumes
author_role author
author2 Lima, Clarissa M. Pinheiro
Andrade, Sonia Gumes
author2_role author
author
dc.contributor.author.fl_str_mv Camandaroba, Edson Luiz Paes
Lima, Clarissa M. Pinheiro
Andrade, Sonia Gumes
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Oral transmission
Experimental intragastric infection; T.cruzi strains infectivity
Biodemes.
topic Trypanosoma cruzi
Oral transmission
Experimental intragastric infection; T.cruzi strains infectivity
Biodemes.
Doença de Chagas/transmissão
Trypanosoma cruzi/patogenicidade
Animais
Doença de Chagas/parasitologia
Doença de Chagas/patologia
Modelos Animais de Doenças
Camundongos
Fatores de Tempo
dc.subject.decs.pt_BR.fl_str_mv Doença de Chagas/transmissão
Trypanosoma cruzi/patogenicidade
Animais
Doença de Chagas/parasitologia
Doença de Chagas/patologia
Modelos Animais de Doenças
Camundongos
Fatores de Tempo
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2012-09-05T20:48:03Z
dc.date.available.fl_str_mv 2012-09-05T20:48:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CAMANDAROBA, E.L.; LIMA, C.M.P.; ANDRADE, S.G.Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection. Revista do Instituto de Medicina Tropical de Sao Paulo, v. 44, n. 2, p. 97-103, mar.-apr. 2002.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/4590
dc.identifier.issn.none.fl_str_mv 0036-4665
identifier_str_mv CAMANDAROBA, E.L.; LIMA, C.M.P.; ANDRADE, S.G.Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection. Revista do Instituto de Medicina Tropical de Sao Paulo, v. 44, n. 2, p. 97-103, mar.-apr. 2002.
0036-4665
url https://www.arca.fiocruz.br/handle/icict/4590
dc.language.iso.fl_str_mv eng
language eng
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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