Chagas disease in the Amazon Region

Detalhes bibliográficos
Autor(a) principal: Aguilar, Hugo Marcelo
Data de Publicação: 2007
Outros Autores: Abad-Franch, Fernando, Dias, João Carlos Pinto, Junqueira, Angela Cristina Verissimo, Coura, José Rodrigues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/1938
Resumo: Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.
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spelling Aguilar, Hugo MarceloAbad-Franch, FernandoDias, João Carlos PintoJunqueira, Angela Cristina VerissimoCoura, José Rodrigues2011-04-22T20:55:02Z2011-04-22T20:55:02Z2007AGUILAR, Hugo Marcelo et al. Chagas disease in the Amazon Region. Memória do Instituto Oswaldo Cruz, Rio de Janeiro, v. 102, suppl. 1, p. 47-55, 2007.0074-0276https://www.arca.fiocruz.br/handle/icict/1938engChagas disease in the Amazon Regioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.The risk that Chagas disease becomes established as a major endemic threat in Amazonia (the world´s largest tropical biome, today inhabited by over 30 million people) relates to a complex set of interacting biological and social determinants. These include intense immigration from endemic areas (possibly introducing parasites and vectors), extensive landscape transformation with uncontrolled deforestation, and the great diversity of wild Trypanosoma cruzi reservoir hosts and vectors (25 species in nine genera), which maintain intense sylvatic transmission cycles. Invasion of houses by adventitious vectors (with infection rates > 60%) is common, and focal adaptation of native triatomines to artificial structures has been reported. Both acute (~ 500) and chronic cases of autochthonous human Chagas disease have been documented beyond doubt in the region. Continuous, low-intensity transmission seems to occur throughout the Amazon, and generates a hypoendemic pattern with seropositivity rates of ~ 1-3%. Discrete foci also exist in which transmission is more intense (e.g., in localized outbreaks probably linked to oral transmission) and prevalence rates higher. Early detection-treatment of acute cases is crucial for avoiding further dispersion of endemic transmission of Chagas disease in Amazonia, and will require the involvement of malaria control and primary health care systems. Comprehensive eco-epidemiological research, including prevalence surveys or the characterization of transmission dynamics in different ecological settings, is still needed. The International Initiative for Chagas Disesae Surveillance and Prevention in the Amazon provides the framework for building up the political and scientific cooperation networks required to confront the challenge of preventing Chagas disease in Amazonia.Chagas diseaseTrypanosoma cruziepidemiologysurveillanceAmazoniainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALChagas disease in the Amazon Region.pdfChagas disease in the Amazon Region.pdfapplication/pdf505204https://www.arca.fiocruz.br/bitstream/icict/1938/1/Chagas%20disease%20in%20the%20Amazon%20Region.pdf2c95c1c6ed6c4bcb7315f7fb059308b1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/1938/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTChagas disease in the Amazon Region.pdf.txtChagas disease in the Amazon Region.pdf.txtExtracted texttext/plain48792https://www.arca.fiocruz.br/bitstream/icict/1938/5/Chagas%20disease%20in%20the%20Amazon%20Region.pdf.txt5ad47bf9d6831d62f10e0560f283b9c7MD55THUMBNAILChagas disease in the Amazon Region.pdf.jpgChagas disease in the Amazon Region.pdf.jpgGenerated Thumbnailimage/jpeg2364https://www.arca.fiocruz.br/bitstream/icict/1938/4/Chagas%20disease%20in%20the%20Amazon%20Region.pdf.jpg4a237e8b28e0fed69d412826ab4ff712MD54icict/19382020-07-17 16:14:39.788oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-07-17T19:14:39Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Chagas disease in the Amazon Region
title Chagas disease in the Amazon Region
spellingShingle Chagas disease in the Amazon Region
Aguilar, Hugo Marcelo
Chagas disease
Trypanosoma cruzi
epidemiology
surveillance
Amazonia
title_short Chagas disease in the Amazon Region
title_full Chagas disease in the Amazon Region
title_fullStr Chagas disease in the Amazon Region
title_full_unstemmed Chagas disease in the Amazon Region
title_sort Chagas disease in the Amazon Region
author Aguilar, Hugo Marcelo
author_facet Aguilar, Hugo Marcelo
Abad-Franch, Fernando
Dias, João Carlos Pinto
Junqueira, Angela Cristina Verissimo
Coura, José Rodrigues
author_role author
author2 Abad-Franch, Fernando
Dias, João Carlos Pinto
Junqueira, Angela Cristina Verissimo
Coura, José Rodrigues
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Aguilar, Hugo Marcelo
Abad-Franch, Fernando
Dias, João Carlos Pinto
Junqueira, Angela Cristina Verissimo
Coura, José Rodrigues
dc.subject.en.pt_BR.fl_str_mv Chagas disease
Trypanosoma cruzi
epidemiology
surveillance
Amazonia
topic Chagas disease
Trypanosoma cruzi
epidemiology
surveillance
Amazonia
description Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2011-04-22T20:55:02Z
dc.date.available.fl_str_mv 2011-04-22T20:55:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv AGUILAR, Hugo Marcelo et al. Chagas disease in the Amazon Region. Memória do Instituto Oswaldo Cruz, Rio de Janeiro, v. 102, suppl. 1, p. 47-55, 2007.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/1938
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv AGUILAR, Hugo Marcelo et al. Chagas disease in the Amazon Region. Memória do Instituto Oswaldo Cruz, Rio de Janeiro, v. 102, suppl. 1, p. 47-55, 2007.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/1938
dc.language.iso.fl_str_mv eng
language eng
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