Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye

Detalhes bibliográficos
Autor(a) principal: Freitas, João Carlos Borges Rolim de
Data de Publicação: 1991
Outros Autores: Presgrave, Octavio Augusto França, Fingola, Fernando Faria, Menezes, Marco Antônio Carneiro, Vasconcellos, Mauricio Carvalho de, Schall, Virgínia Torres, Paumgartten, Francisco José Roma
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1590/S0074-02761991000600021
Texto Completo: https://www.arca.fiocruz.br/handle/icict/11968
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.
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spelling Freitas, João Carlos Borges Rolim dePresgrave, Octavio Augusto FrançaFingola, Fernando FariaMenezes, Marco Antônio CarneiroVasconcellos, Mauricio Carvalho deSchall, Virgínia TorresPaumgartten, Francisco José Roma2015-10-16T18:55:17Z2015-10-16T18:55:17Z1991FREITAS, João Carlos Borges Rolim de et al. Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 86, supl. 2, p. 87-88, 1991.0074-0276https://www.arca.fiocruz.br/handle/icict/1196810.1590/S0074-02761991000600021engInstituto Oswaldo CruzEuphorbia SplendensEsquistossomoseIrritação CutâneaIrritação OcularEuphorbia SplendensPlants MolluscicideSchistosomiasisSkin IrritationEye IrritationToxicologyEuphorbiaEsquistossomoseTestes de Irritação da PeleToxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eyeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.Aqueous solutions of the molluscicidal latex of Euphorbia splendens are irritant to the rabbit eye in concentrations higher than 0.35% and to the rabbit skin in concentrations higher than 0.5%. Although this irritant potential does not proclude its use as a molluscicide, special precautions are recommended for hanbdling and application of the product and the hazard of skin tumor-promoting potencial should be carefully investigated before its use for schistosomiasis vector control.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82354https://www.arca.fiocruz.br/bitstream/icict/11968/1/license.txt8b4c200b4e10021c5683c6ccaba07169MD51ORIGINALMIOC_86_87-88.pdfMIOC_86_87-88.pdfapplication/pdf114737https://www.arca.fiocruz.br/bitstream/icict/11968/2/MIOC_86_87-88.pdf8ed9681c306433f9840ecfdc3955bec0MD52TEXTMIOC_86_87-88.pdf.txtMIOC_86_87-88.pdf.txtExtracted texttext/plain2https://www.arca.fiocruz.br/bitstream/icict/11968/3/MIOC_86_87-88.pdf.txte1c06d85ae7b8b032bef47e42e4c08f9MD53icict/119682019-04-20 19:03:33.139oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-04-20T22:03:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en.fl_str_mv Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
title Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
spellingShingle Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
Freitas, João Carlos Borges Rolim de
Euphorbia Splendens
Esquistossomose
Irritação Cutânea
Irritação Ocular
Euphorbia Splendens
Plants Molluscicide
Schistosomiasis
Skin Irritation
Eye Irritation
Toxicology
Euphorbia
Esquistossomose
Testes de Irritação da Pele
title_short Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
title_full Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
title_fullStr Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
title_full_unstemmed Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
title_sort Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
author Freitas, João Carlos Borges Rolim de
author_facet Freitas, João Carlos Borges Rolim de
Presgrave, Octavio Augusto França
Fingola, Fernando Faria
Menezes, Marco Antônio Carneiro
Vasconcellos, Mauricio Carvalho de
Schall, Virgínia Torres
Paumgartten, Francisco José Roma
author_role author
author2 Presgrave, Octavio Augusto França
Fingola, Fernando Faria
Menezes, Marco Antônio Carneiro
Vasconcellos, Mauricio Carvalho de
Schall, Virgínia Torres
Paumgartten, Francisco José Roma
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, João Carlos Borges Rolim de
Presgrave, Octavio Augusto França
Fingola, Fernando Faria
Menezes, Marco Antônio Carneiro
Vasconcellos, Mauricio Carvalho de
Schall, Virgínia Torres
Paumgartten, Francisco José Roma
dc.subject.other.pt_BR.fl_str_mv Euphorbia Splendens
Esquistossomose
Irritação Cutânea
Irritação Ocular
topic Euphorbia Splendens
Esquistossomose
Irritação Cutânea
Irritação Ocular
Euphorbia Splendens
Plants Molluscicide
Schistosomiasis
Skin Irritation
Eye Irritation
Toxicology
Euphorbia
Esquistossomose
Testes de Irritação da Pele
dc.subject.en.en.fl_str_mv Euphorbia Splendens
Plants Molluscicide
Schistosomiasis
Skin Irritation
Eye Irritation
Toxicology
dc.subject.decs.pt_BR.fl_str_mv Euphorbia
Esquistossomose
Testes de Irritação da Pele
description Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Farmacologia e Toxicologia. Rio de Janeiro, RJ, Brasil.
publishDate 1991
dc.date.issued.fl_str_mv 1991
dc.date.accessioned.fl_str_mv 2015-10-16T18:55:17Z
dc.date.available.fl_str_mv 2015-10-16T18:55:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv FREITAS, João Carlos Borges Rolim de et al. Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 86, supl. 2, p. 87-88, 1991.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/11968
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761991000600021
identifier_str_mv FREITAS, João Carlos Borges Rolim de et al. Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 86, supl. 2, p. 87-88, 1991.
0074-0276
10.1590/S0074-02761991000600021
url https://www.arca.fiocruz.br/handle/icict/11968
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz
publisher.none.fl_str_mv Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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