The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil

Detalhes bibliográficos
Autor(a) principal: Neiva, Vanessa Lima
Data de Publicação: 2021
Outros Autores: Toma, Helena Keiko, Aguiar, Lúcia Maria Abrantes, Lopes, Catarina Macedo, Dias, Letícia Paschoaletto, Gonçalves, Teresa Cristina Monte, Costa, Jane
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1371/journal. pntd.0009919
Texto Completo: https://www.arca.fiocruz.br/handle/icict/50199
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade Entomológica. Rio de Janeiro, RJ, Brasil.
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spelling Neiva, Vanessa LimaToma, Helena KeikoAguiar, Lúcia Maria AbrantesLopes, Catarina MacedoDias, Letícia PaschoalettoGonçalves, Teresa Cristina MonteCosta, Jane2021-12-07T13:22:03Z2021-12-07T13:22:03Z2021NEIVA, Vanessa Lima et al. The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil. Plos Negl. Trop. Dis, v. 15, n. 11, e0009919, p. 1 - 21, Nov. 2021.1935-2727https://www.arca.fiocruz.br/handle/icict/5019910.1371/journal. pntd.0009919engPublic Library of ScienceTrypanosoma cruziCiclos de transmissãoTriatoma brasiliensis brasiliensisSaúde humanaÁrea suscetível à desertificaçãoSeridó, Rio Grande do NorteTrypanosoma cruziTransmission cyclesTriatoma brasiliensis brasiliensisHuman healthArea susceptible desertificationSeridó, Rio Grande do NorteBrasilThe connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade Entomológica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Laboratório de Diagnóstico Molecular e Hematologia. Rio de Janeiro, RJ, Brasil.Secretaria de Estado da Saúde Pública. Natal, RN, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Vigilância Entomológica em Diptera e Hemiptera. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade Entomológica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Vigilância Entomológica em Diptera e Hemiptera. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade Entomológica. Rio de Janeiro, RJ, Brasil.An outbreak of Chagas disease, possibly involving its vector Triatoma brasiliensis brasiliensis, was identified in the state of Rio Grande do Norte (RN). Given the historical significance of this vector in public health, the study aimed to evaluate its role in the transmission dynamics of the protozoan Trypanosoma cruzi in an area undergoing desertification in the Serido´ region, RN, Brazil. We captured triatomines in sylvatic and anthropic ecotopes. Natural vector infection was determined using parasitological and molecular methods and we identified discrete typing units (DTUs) of T. cruzi by analyzing the COII gene of mtDNA, 24Sα rDNA, and mini-exon gene. Their blood meals sources were identified by amplification and sequencing of the mtDNA cytochrome b gene. A total of 952 T. b. brasiliensis were captured in peridomestic (69.9%) and sylvatic ecotopes (30.4%). A wide range of natural infection rates were observed in peridomestic (36.0% - 71.1%) and sylvatic populations (28.6% - 100.0%). We observed the circulation of TcI and TcII DTUs with a predominance of Tcl in sylvatic and peridomestic environments. Kerodon rupestris, rocky cavy (13/39), Homo sapiens, human (8/39), and Bos taurus, ox (6/39) were the most frequently detected blood meals sources. Thus, Triatoma b. brasiliensis is invading and colonizing the human dwellings. Furthermore, high levels of natural infection, coupled with the detection of TcI and TcII DTUs, and also the detection of K. rupestris and H. sapiens as blood meals sources of infected T. b. brasiliensis indicate a risk of T. cruzi transmission to human populations in areas undergoing desertification.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/50199/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALVanessaNeiva_TeresaGonçalves_etal_IOC_2021.pdfVanessaNeiva_TeresaGonçalves_etal_IOC_2021.pdfapplication/pdf1468077https://www.arca.fiocruz.br/bitstream/icict/50199/2/VanessaNeiva_TeresaGon%c3%a7alves_etal_IOC_2021.pdf466db730f70fda8d11569ea014171679MD52icict/501992021-12-07 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dc.title.pt_BR.fl_str_mv The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
title The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
spellingShingle The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
Neiva, Vanessa Lima
Trypanosoma cruzi
Ciclos de transmissão
Triatoma brasiliensis brasiliensis
Saúde humana
Área suscetível à desertificação
Seridó, Rio Grande do Norte
Trypanosoma cruzi
Transmission cycles
Triatoma brasiliensis brasiliensis
Human health
Area susceptible desertification
Seridó, Rio Grande do Norte
Brasil
title_short The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
title_full The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
title_fullStr The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
title_full_unstemmed The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
title_sort The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil
author Neiva, Vanessa Lima
author_facet Neiva, Vanessa Lima
Toma, Helena Keiko
Aguiar, Lúcia Maria Abrantes
Lopes, Catarina Macedo
Dias, Letícia Paschoaletto
Gonçalves, Teresa Cristina Monte
Costa, Jane
author_role author
author2 Toma, Helena Keiko
Aguiar, Lúcia Maria Abrantes
Lopes, Catarina Macedo
Dias, Letícia Paschoaletto
Gonçalves, Teresa Cristina Monte
Costa, Jane
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Neiva, Vanessa Lima
Toma, Helena Keiko
Aguiar, Lúcia Maria Abrantes
Lopes, Catarina Macedo
Dias, Letícia Paschoaletto
Gonçalves, Teresa Cristina Monte
Costa, Jane
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Ciclos de transmissão
Triatoma brasiliensis brasiliensis
Saúde humana
Área suscetível à desertificação
Seridó, Rio Grande do Norte
topic Trypanosoma cruzi
Ciclos de transmissão
Triatoma brasiliensis brasiliensis
Saúde humana
Área suscetível à desertificação
Seridó, Rio Grande do Norte
Trypanosoma cruzi
Transmission cycles
Triatoma brasiliensis brasiliensis
Human health
Area susceptible desertification
Seridó, Rio Grande do Norte
Brasil
dc.subject.en.pt_BR.fl_str_mv Trypanosoma cruzi
Transmission cycles
Triatoma brasiliensis brasiliensis
Human health
Area susceptible desertification
Seridó, Rio Grande do Norte
Brasil
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade Entomológica. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-12-07T13:22:03Z
dc.date.available.fl_str_mv 2021-12-07T13:22:03Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NEIVA, Vanessa Lima et al. The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil. Plos Negl. Trop. Dis, v. 15, n. 11, e0009919, p. 1 - 21, Nov. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/50199
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal. pntd.0009919
identifier_str_mv NEIVA, Vanessa Lima et al. The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Serido´, Rio Grande do Norte, Brazil. Plos Negl. Trop. Dis, v. 15, n. 11, e0009919, p. 1 - 21, Nov. 2021.
1935-2727
10.1371/journal. pntd.0009919
url https://www.arca.fiocruz.br/handle/icict/50199
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
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collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/50199/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/50199/2/VanessaNeiva_TeresaGon%c3%a7alves_etal_IOC_2021.pdf
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