Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/30961 |
Resumo: | Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil. |
| id |
CRUZ_233f1e3570a0291d81d710e7a3a79971 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/30961 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Costa, Elis R. DallaRibeiro, Marta O.Silva, Márcia S. N.Arnold, Liane S.Rostirolla, Diana C.Cafrune, Patricia I.Espinoza, Roger C.Palaci, MoisesTelles, Maria A.Ritacco, VivianaSuffys, Philip N.Lopes, Maria L.Campelo, Creuza L.Miranda, Silvana S.Kremer, KristinSilva, Pedro E. Almeida daFonseca, Leila de SouzaHo, John L.Kritski, Afrânio L.Rossetti, Maria L. R.2019-01-10T13:50:36Z2019-01-10T13:50:36Z2009DALLA COSTA, Elis R. et al. Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America. BMC Microbiology, v. 9, n. 39, p. 1-11, Feb. 2009.1471-2180https://www.arca.fiocruz.br/handle/icict/3096110.1186/1471-2180-9-39engBioMed CentralMycobacterium tuberculosisMutaçõesGenes katG, oxyR-ahpC e inhALinhagens clínicasAmílias de espoligotiposAmérica do SulTuberculoseMycobacterium tuberculosisOxyR-ahpC and inhA genesMutationsSpoligotype familiesTuberculosisSouth AmericaClinical strainsCorrelations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South Americainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleOswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Luterana University of Brazil. Rio de Janeiro, RJ, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Federal University of Rio Grande do Sul. Porto Alegre, RS, Brazil.Blufstein Clinic Laboratory. Lima, Peru.Federal University of Espírito Santo. Vitória, ES, Brazil.Adolfo Lutz Institute. São Paulo, SP, Brazil.Instittuto Nacional Enfermedades Infecciosas. Servicio de Micobacterias. Argentina.Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil.Evandro Chagas Institute. Manaus, AM, Brazil.LACEN. Fortaleza, CE, Brazil.Federal University of Minas Gerais. Belo Horizonte, MG, Brazil.National Institute for Public Health and the Environment. Mycobacteria Reference Unit. Amsterdã, Netherlands.Federal Foundation of Rio Grande. Porto Alegre, RS, Brazil.Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil.Cornell University, Ithaca. New York, USA.Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil.State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Luterana University of Brazil. Rio de Janeiro, RJ, Brazil / Fundação Estadual de Produção e Pesquisa em Saúde. Centro de Desenvolvimento Científico e Tecnológico. Porto Alegre, RS, Brazil.Mutations associated with resistance to rifampin or streptomycin have been reported for W/Beijing and Latin American Mediterranean (LAM) strain families of Mycobacterium tuberculosis. A few studies with limited sample sizes have separately evaluated mutations in katG, ahpC and inhA genes that are associated with isoniazid (INH) resistance. Increasing prevalence of INH resistance, especially in high tuberculosis (TB) prevalent countries is worsening the burden of TB control programs, since similar transmission rates are noted for INH susceptible and resistant M. tuberculosis strains.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30961/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALphylip_suffys_etal_IOC_2009.pdfphylip_suffys_etal_IOC_2009.pdfapplication/pdf282699https://www.arca.fiocruz.br/bitstream/icict/30961/2/phylip_suffys_etal_IOC_2009.pdf5838fe1def904e3c6d21ec114499e546MD52TEXTphylip_suffys_etal_IOC_2009.pdf.txtphylip_suffys_etal_IOC_2009.pdf.txtExtracted texttext/plain48331https://www.arca.fiocruz.br/bitstream/icict/30961/3/phylip_suffys_etal_IOC_2009.pdf.txt8f33e43f2989e73d69ee7dcae0182580MD53icict/309612023-09-05 10:02:12.852oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-05T13:02:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| title |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| spellingShingle |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America Costa, Elis R. Dalla Mycobacterium tuberculosis Mutações Genes katG, oxyR-ahpC e inhA Linhagens clínicas Amílias de espoligotipos América do Sul Tuberculose Mycobacterium tuberculosis OxyR-ahpC and inhA genes Mutations Spoligotype families Tuberculosis South America Clinical strains |
| title_short |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| title_full |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| title_fullStr |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| title_full_unstemmed |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| title_sort |
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America |
| author |
Costa, Elis R. Dalla |
| author_facet |
Costa, Elis R. Dalla Ribeiro, Marta O. Silva, Márcia S. N. Arnold, Liane S. Rostirolla, Diana C. Cafrune, Patricia I. Espinoza, Roger C. Palaci, Moises Telles, Maria A. Ritacco, Viviana Suffys, Philip N. Lopes, Maria L. Campelo, Creuza L. Miranda, Silvana S. Kremer, Kristin Silva, Pedro E. Almeida da Fonseca, Leila de Souza Ho, John L. Kritski, Afrânio L. Rossetti, Maria L. R. |
| author_role |
author |
| author2 |
Ribeiro, Marta O. Silva, Márcia S. N. Arnold, Liane S. Rostirolla, Diana C. Cafrune, Patricia I. Espinoza, Roger C. Palaci, Moises Telles, Maria A. Ritacco, Viviana Suffys, Philip N. Lopes, Maria L. Campelo, Creuza L. Miranda, Silvana S. Kremer, Kristin Silva, Pedro E. Almeida da Fonseca, Leila de Souza Ho, John L. Kritski, Afrânio L. Rossetti, Maria L. R. |
| author2_role |
author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Costa, Elis R. Dalla Ribeiro, Marta O. Silva, Márcia S. N. Arnold, Liane S. Rostirolla, Diana C. Cafrune, Patricia I. Espinoza, Roger C. Palaci, Moises Telles, Maria A. Ritacco, Viviana Suffys, Philip N. Lopes, Maria L. Campelo, Creuza L. Miranda, Silvana S. Kremer, Kristin Silva, Pedro E. Almeida da Fonseca, Leila de Souza Ho, John L. Kritski, Afrânio L. Rossetti, Maria L. R. |
| dc.subject.other.pt_BR.fl_str_mv |
Mycobacterium tuberculosis Mutações Genes katG, oxyR-ahpC e inhA Linhagens clínicas Amílias de espoligotipos América do Sul Tuberculose |
| topic |
Mycobacterium tuberculosis Mutações Genes katG, oxyR-ahpC e inhA Linhagens clínicas Amílias de espoligotipos América do Sul Tuberculose Mycobacterium tuberculosis OxyR-ahpC and inhA genes Mutations Spoligotype families Tuberculosis South America Clinical strains |
| dc.subject.en.pt_BR.fl_str_mv |
Mycobacterium tuberculosis OxyR-ahpC and inhA genes Mutations Spoligotype families Tuberculosis South America Clinical strains |
| description |
Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil. |
| publishDate |
2009 |
| dc.date.issued.fl_str_mv |
2009 |
| dc.date.accessioned.fl_str_mv |
2019-01-10T13:50:36Z |
| dc.date.available.fl_str_mv |
2019-01-10T13:50:36Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
DALLA COSTA, Elis R. et al. Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America. BMC Microbiology, v. 9, n. 39, p. 1-11, Feb. 2009. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/30961 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1471-2180 |
| dc.identifier.doi.none.fl_str_mv |
10.1186/1471-2180-9-39 |
| identifier_str_mv |
DALLA COSTA, Elis R. et al. Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America. BMC Microbiology, v. 9, n. 39, p. 1-11, Feb. 2009. 1471-2180 10.1186/1471-2180-9-39 |
| url |
https://www.arca.fiocruz.br/handle/icict/30961 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
BioMed Central |
| publisher.none.fl_str_mv |
BioMed Central |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/30961/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/30961/2/phylip_suffys_etal_IOC_2009.pdf https://www.arca.fiocruz.br/bitstream/icict/30961/3/phylip_suffys_etal_IOC_2009.pdf.txt |
| bitstream.checksum.fl_str_mv |
5a560609d32a3863062d77ff32785d58 5838fe1def904e3c6d21ec114499e546 8f33e43f2989e73d69ee7dcae0182580 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813009006439956480 |