Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody

Detalhes bibliográficos
Autor(a) principal: Pontes, Larissa Queiroz
Data de Publicação: 2019
Outros Autores: Bezerra, Marcus Rafael Lobo, Fonseca, Marcela Helena Gambim, Lourenzoni, Marcos Roberto, Furtado, Gilvan Pessoa
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32703
Resumo: Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.
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spelling Pontes, Larissa QueirozBezerra, Marcus Rafael LoboFonseca, Marcela Helena GambimLourenzoni, Marcos RobertoFurtado, Gilvan Pessoa2019-04-24T13:26:24Z2019-04-24T13:26:24Z2019PONTES, L. Q. et al. Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 99.https://www.arca.fiocruz.br/handle/icict/3270310.35259/isi.sact.2019_32703Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.Universidade Federal do Ceará. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Fiocruz Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Fiocruz Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Fiocruz Ceará. Fortaleza, CE, Brasil.engFiocruz/Instituto de Tecnologia em ImunobiológicosEngenharia de AnticorposMutagênese Sítio-DirigidaRituximabAntibody engineeringSite-directed mutagenesisRituximabMutagênese Sítio-DirigidaRituximabConstruction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibodyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32703/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALBIO_14.pdfapplication/pdf64380https://www.arca.fiocruz.br/bitstream/icict/32703/2/BIO_14.pdfdcfa93c6c24d55715a6c947691388677MD52TEXTBIO_14.pdf.txtBIO_14.pdf.txtExtracted texttext/plain3310https://www.arca.fiocruz.br/bitstream/icict/32703/3/BIO_14.pdf.txtc43dde845069760a96c293aa1904fc87MD53icict/327032023-04-26 17:00:44.042oai:www.arca.fiocruz.br:icict/32703Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-26T20:00:44Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
title Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
spellingShingle Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
Pontes, Larissa Queiroz
Engenharia de Anticorpos
Mutagênese Sítio-Dirigida
Rituximab
Antibody engineering
Site-directed mutagenesis
Rituximab
Mutagênese Sítio-Dirigida
Rituximab
title_short Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
title_full Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
title_fullStr Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
title_full_unstemmed Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
title_sort Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
author Pontes, Larissa Queiroz
author_facet Pontes, Larissa Queiroz
Bezerra, Marcus Rafael Lobo
Fonseca, Marcela Helena Gambim
Lourenzoni, Marcos Roberto
Furtado, Gilvan Pessoa
author_role author
author2 Bezerra, Marcus Rafael Lobo
Fonseca, Marcela Helena Gambim
Lourenzoni, Marcos Roberto
Furtado, Gilvan Pessoa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pontes, Larissa Queiroz
Bezerra, Marcus Rafael Lobo
Fonseca, Marcela Helena Gambim
Lourenzoni, Marcos Roberto
Furtado, Gilvan Pessoa
dc.subject.other.pt_BR.fl_str_mv Engenharia de Anticorpos
Mutagênese Sítio-Dirigida
Rituximab
topic Engenharia de Anticorpos
Mutagênese Sítio-Dirigida
Rituximab
Antibody engineering
Site-directed mutagenesis
Rituximab
Mutagênese Sítio-Dirigida
Rituximab
dc.subject.en.pt_BR.fl_str_mv Antibody engineering
Site-directed mutagenesis
Rituximab
dc.subject.decs.pt_BR.fl_str_mv Mutagênese Sítio-Dirigida
Rituximab
description Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-04-24T13:26:24Z
dc.date.available.fl_str_mv 2019-04-24T13:26:24Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.citation.fl_str_mv PONTES, L. Q. et al. Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 99.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32703
dc.identifier.doi.none.fl_str_mv 10.35259/isi.sact.2019_32703
identifier_str_mv PONTES, L. Q. et al. Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 99.
10.35259/isi.sact.2019_32703
url https://www.arca.fiocruz.br/handle/icict/32703
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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