Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis

Detalhes bibliográficos
Autor(a) principal: Rodrigues, A. B. F
Data de Publicação: 2010
Outros Autores: Ristow, Paula, Santos, A. S. O, Lilenbaum, W, Fonseca, L. S, Carvalho, C. B, Carvalho, E. C. Q
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/6050
Resumo: Universidade Estadual do Norte Fluminense Darcy Ribeiro. Campos dos Goytacazes, RJ, Brasil
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spelling Rodrigues, A. B. FRistow, PaulaSantos, A. S. OLilenbaum, WFonseca, L. SCarvalho, C. BCarvalho, E. C. Q2012-12-20T20:37:23Z2012-12-20T20:37:23Z2010RODRIGUES, A. B. F. et al. Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 62, n. 6, p. 1495-1498, dez. 2010.0102-0935https://www.arca.fiocruz.br/handle/icict/6050porBovinoParatuberculoseHepatiteHistopatologiaBovineParatuberculosisHepatitisHistopathologyHepatite/patologiaMycobacterium/patogenicidadeParatuberculoseBovinosHepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Estadual do Norte Fluminense Darcy Ribeiro. Campos dos Goytacazes, RJ, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilInstituto Federal de Educação do Pará . Belém, PA, BrasilUniversidade Federal Fluminense. Niterói, RJ, BrasilUniversidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, BrasilUniversidade Estadual do Norte Fluminense Darcy Ribeiro. Campos dos Goytacazes, RJ, BrasilUniversidade Estadual do Norte Fluminense Darcy Ribeiro. Campos dos Goytacazes, RJ, BrasilSamples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection of acid-fast bacilli (AFB), and submitted to immunohistochemistry (IHC). Macroscopic changes were observed in the small intestines, with thickening and corrugation of the mucosa. The main microscopic changes were found in small intestines, lymph vessels in the mesentery, and mesenteric lymph nodes characterized by enteritis, lymphangiectasia, and lymphadenitis. Liver presented with granulomatous hepatitis, an uncommon histopathological feature for paratuberculosis. The clinical features associated with positive culture of Mycobacterium avium subsp. paratuberculosis and detection of AFB by ZN and IHC in the cytoplasm of macrophages (epithelioid) in the intestinal mucosa and submucosa, lymph nodes, and liver were important to confirm the diagnosis of paratuberculosis.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALRodrigues ABF Hepatite granulomatosa....pdfRodrigues ABF Hepatite granulomatosa....pdfapplication/pdf211308https://www.arca.fiocruz.br/bitstream/icict/6050/1/Rodrigues%20ABF%20Hepatite%20granulomatosa....pdf271f4c0a1e7a3fcd08d2ba926ec67560MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/6050/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTRodrigues ABF Hepatite granulomatosa....pdf.txtRodrigues ABF Hepatite granulomatosa....pdf.txtExtracted texttext/plain14823https://www.arca.fiocruz.br/bitstream/icict/6050/5/Rodrigues%20ABF%20Hepatite%20granulomatosa....pdf.txt0926b00fd9f919e9730a9c8b45c62c9cMD55THUMBNAILRodrigues ABF Hepatite granulomatosa....pdf.jpgRodrigues ABF Hepatite granulomatosa....pdf.jpgGenerated Thumbnailimage/jpeg1679https://www.arca.fiocruz.br/bitstream/icict/6050/4/Rodrigues%20ABF%20Hepatite%20granulomatosa....pdf.jpg69c71bbabe683a9a23f90d12633a82b9MD54icict/60502023-03-15 14:32:57.739oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:57Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
title Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
spellingShingle Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
Rodrigues, A. B. F
Bovino
Paratuberculose
Hepatite
Histopatologia
Bovine
Paratuberculosis
Hepatitis
Histopathology
Hepatite/patologia
Mycobacterium/patogenicidade
Paratuberculose
Bovinos
title_short Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
title_full Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
title_fullStr Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
title_full_unstemmed Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
title_sort Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
author Rodrigues, A. B. F
author_facet Rodrigues, A. B. F
Ristow, Paula
Santos, A. S. O
Lilenbaum, W
Fonseca, L. S
Carvalho, C. B
Carvalho, E. C. Q
author_role author
author2 Ristow, Paula
Santos, A. S. O
Lilenbaum, W
Fonseca, L. S
Carvalho, C. B
Carvalho, E. C. Q
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rodrigues, A. B. F
Ristow, Paula
Santos, A. S. O
Lilenbaum, W
Fonseca, L. S
Carvalho, C. B
Carvalho, E. C. Q
dc.subject.other.pt_BR.fl_str_mv Bovino
Paratuberculose
Hepatite
Histopatologia
topic Bovino
Paratuberculose
Hepatite
Histopatologia
Bovine
Paratuberculosis
Hepatitis
Histopathology
Hepatite/patologia
Mycobacterium/patogenicidade
Paratuberculose
Bovinos
dc.subject.en.pt_BR.fl_str_mv Bovine
Paratuberculosis
Hepatitis
Histopathology
dc.subject.decs.pt_BR.fl_str_mv Hepatite/patologia
Mycobacterium/patogenicidade
Paratuberculose
Bovinos
description Universidade Estadual do Norte Fluminense Darcy Ribeiro. Campos dos Goytacazes, RJ, Brasil
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-12-20T20:37:23Z
dc.date.available.fl_str_mv 2012-12-20T20:37:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RODRIGUES, A. B. F. et al. Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 62, n. 6, p. 1495-1498, dez. 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/6050
dc.identifier.issn.none.fl_str_mv 0102-0935
identifier_str_mv RODRIGUES, A. B. F. et al. Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 62, n. 6, p. 1495-1498, dez. 2010.
0102-0935
url https://www.arca.fiocruz.br/handle/icict/6050
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