Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25656 |
Resumo: | Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) under the notice number 020/201- Research Program: shared health management ± (PPSUS) of Bahia (award number: EFP00006943). |
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Teixeira, Rozana SantosRamos, Regina TerseFerreira, Tatiane AnunciaçãoMachado, Vinícius RamosPerdiz, Marya IzadoraLyra, Isa MenezesNascimento, Valma LopesBoa Sorte, NeyAndrade, Bruno de BezerrilLadeia, Ana Marice Teixeira2018-04-06T14:13:18Z2018-04-06T14:13:18Z2017TEIXEIRA, Rozana Santos et al. Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. PLoS One, v. 12, n. 9, p. e0184076, 2017.1932-6203https://www.arca.fiocruz.br/handle/icict/2565610.1371/journal.pone.0184076Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) under the notice number 020/201- Research Program: shared health management ± (PPSUS) of Bahia (award number: EFP00006943).Bahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil / Federal University of Bahia. School of Medicine. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Salvador, BA, BrazilBahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil / Federal University of Bahia. School of Medicine. Salvador, BA, BrazilBahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil /Bahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil /University Salvador. Laureate International Universities. Salvador, BA, BrazilHematology and Hemotherapy Foundation of Bahia. Salvador, BA, BrazilBahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, BrazilBahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil / University Salvador. Laureate International Universities. Salvador, BA, Brazil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brazil / University of Salvador. Salvador, BA, Brazil / Fundação José Silveira. Multinational Organization Network Sponsoring Translational and Epidemiological Research Initiative. Salvador, BA, BrazilBahia Foundation for the Development of Sciences. Bahiana School of Medicine Public Health. Salvador, BA, Brazil / Catholic University of Salvador. Salvador, BA, BrazilHematological changes can drive damage of endothelial cells, which potentially lead to an early endothelial dysfunction in patients with sickle cell anemia (SCA). An association may exist between endothelial dysfunction and several clinical manifestations of SCA. The present study aims to evaluate the links between changes in endothelial function and clinical and laboratory parameters in children and adolescents with SCA.engPublic Library of ScienceAnemia FalciformeCélulas endoteliaisReticulócitosUltrassonografia DopplerAdolescenteCriançaAnemia SickleEndothelial CellsReticulocytesUltrasonography, DopplerAdolescentChildAssociations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25656/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALTeixeira RS Associations between endothelial....pdfTeixeira RS Associations between 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14:33:02.172oai:www.arca.fiocruz.br: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ório 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dc.title.pt_BR.fl_str_mv |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
title |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
spellingShingle |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia Teixeira, Rozana Santos Anemia Falciforme Células endoteliais Reticulócitos Ultrassonografia Doppler Adolescente Criança Anemia Sickle Endothelial Cells Reticulocytes Ultrasonography, Doppler Adolescent Child |
title_short |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
title_full |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
title_fullStr |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
title_full_unstemmed |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
title_sort |
Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia |
author |
Teixeira, Rozana Santos |
author_facet |
Teixeira, Rozana Santos Ramos, Regina Terse Ferreira, Tatiane Anunciação Machado, Vinícius Ramos Perdiz, Marya Izadora Lyra, Isa Menezes Nascimento, Valma Lopes Boa Sorte, Ney Andrade, Bruno de Bezerril Ladeia, Ana Marice Teixeira |
author_role |
author |
author2 |
Ramos, Regina Terse Ferreira, Tatiane Anunciação Machado, Vinícius Ramos Perdiz, Marya Izadora Lyra, Isa Menezes Nascimento, Valma Lopes Boa Sorte, Ney Andrade, Bruno de Bezerril Ladeia, Ana Marice Teixeira |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Teixeira, Rozana Santos Ramos, Regina Terse Ferreira, Tatiane Anunciação Machado, Vinícius Ramos Perdiz, Marya Izadora Lyra, Isa Menezes Nascimento, Valma Lopes Boa Sorte, Ney Andrade, Bruno de Bezerril Ladeia, Ana Marice Teixeira |
dc.subject.other.pt_BR.fl_str_mv |
Anemia Falciforme Células endoteliais Reticulócitos Ultrassonografia Doppler Adolescente Criança |
topic |
Anemia Falciforme Células endoteliais Reticulócitos Ultrassonografia Doppler Adolescente Criança Anemia Sickle Endothelial Cells Reticulocytes Ultrasonography, Doppler Adolescent Child |
dc.subject.en.pt_BR.fl_str_mv |
Anemia Sickle Endothelial Cells Reticulocytes Ultrasonography, Doppler Adolescent Child |
description |
Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) under the notice number 020/201- Research Program: shared health management ± (PPSUS) of Bahia (award number: EFP00006943). |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2018-04-06T14:13:18Z |
dc.date.available.fl_str_mv |
2018-04-06T14:13:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
TEIXEIRA, Rozana Santos et al. Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. PLoS One, v. 12, n. 9, p. e0184076, 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/25656 |
dc.identifier.issn.pt_BR.fl_str_mv |
1932-6203 |
dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pone.0184076 |
identifier_str_mv |
TEIXEIRA, Rozana Santos et al. Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. PLoS One, v. 12, n. 9, p. e0184076, 2017. 1932-6203 10.1371/journal.pone.0184076 |
url |
https://www.arca.fiocruz.br/handle/icict/25656 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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Public Library of Science |
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Public Library of Science |
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