Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy

Detalhes bibliográficos
Autor(a) principal: Leite, A. C. C. B.
Data de Publicação: 2004
Outros Autores: Silva, M. T. T., Alamy, A. H., Afonso, C. R., Lima, M. A., Serpa, M. J. A., Nascimento, O. J., Araújo, A. Q. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32991
Resumo: 2020-05-08
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spelling Leite, A. C. C. B.Silva, M. T. T.Alamy, A. H.Afonso, C. R.Lima, M. A.Serpa, M. J. A.Nascimento, O. J.Araújo, A. Q. C.2019-05-08T13:03:43Z2019-05-08T13:03:43Z2004LEITE, Ana C. C. L. et al. Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy. Journal of Neurology, v. 251, n. 7, p. 877-881, July 2004.0340-5354https://www.arca.fiocruz.br/handle/icict/3299110.1007/s00415-004-0455-71432-1459engSpringer VerlagPeripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-05-08Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Fluminense Federal University. Service of Neurology. Niterói, RJ, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Fluminense Federal University. Service of Neurology. Niterói, RJ, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Centro de Referência em Neuroinfecções e HTLV. Rio de Janeiro, RJ, Brasil.Tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) is the classical neurological manifestation of HTLV-I. Only a few studies have described isolated peripheral neuropathy (PN) among HTLV-I infected individuals. 335 infected individuals without TSP/HAM were evaluated for the presence of PN and 45 of them showed evidences of peripheral nervous system involvement. Of these 21 patients had isolated PN, defined by clinical and/or electrophysiological criteria. Sural nerve biopsies revealed inflammatory infiltrates in 2, axonal degeneration in 2 and segmental demyelination in 1. Therefore, peripheral neuropathy can be found as an isolated manifestation of HTLV-I infection. We conclude that HTLV-I infection should be investigated in patients with PN of unknown origin.HTLV-IPeripheral neuropathyTSP/HAMinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32991/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Leite_Ana_etal_INI_2004.pdfve_Leite_Ana_etal_INI_2004.pdfapplication/pdf262218https://www.arca.fiocruz.br/bitstream/icict/32991/2/ve_Leite_Ana_etal_INI_2004.pdfb9255fd7655f75f883a268ed226b69e3MD52TEXTve_Leite_Ana_etal_INI_2004.pdf.txtve_Leite_Ana_etal_INI_2004.pdf.txtExtracted texttext/plain19930https://www.arca.fiocruz.br/bitstream/icict/32991/3/ve_Leite_Ana_etal_INI_2004.pdf.txt7cc13bb9b5612054097272f7d4491405MD53icict/329912021-03-24 16:32:31.486oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:31Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
title Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
spellingShingle Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
Leite, A. C. C. B.
HTLV-I
Peripheral neuropathy
TSP/HAM
title_short Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
title_full Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
title_fullStr Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
title_full_unstemmed Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
title_sort Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
author Leite, A. C. C. B.
author_facet Leite, A. C. C. B.
Silva, M. T. T.
Alamy, A. H.
Afonso, C. R.
Lima, M. A.
Serpa, M. J. A.
Nascimento, O. J.
Araújo, A. Q. C.
author_role author
author2 Silva, M. T. T.
Alamy, A. H.
Afonso, C. R.
Lima, M. A.
Serpa, M. J. A.
Nascimento, O. J.
Araújo, A. Q. C.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Leite, A. C. C. B.
Silva, M. T. T.
Alamy, A. H.
Afonso, C. R.
Lima, M. A.
Serpa, M. J. A.
Nascimento, O. J.
Araújo, A. Q. C.
dc.subject.en.pt_BR.fl_str_mv HTLV-I
Peripheral neuropathy
TSP/HAM
topic HTLV-I
Peripheral neuropathy
TSP/HAM
description 2020-05-08
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2019-05-08T13:03:43Z
dc.date.available.fl_str_mv 2019-05-08T13:03:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LEITE, Ana C. C. L. et al. Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy. Journal of Neurology, v. 251, n. 7, p. 877-881, July 2004.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32991
dc.identifier.issn.pt_BR.fl_str_mv 0340-5354
dc.identifier.doi.none.fl_str_mv 10.1007/s00415-004-0455-7
dc.identifier.eissn.none.fl_str_mv 1432-1459
identifier_str_mv LEITE, Ana C. C. L. et al. Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy. Journal of Neurology, v. 251, n. 7, p. 877-881, July 2004.
0340-5354
10.1007/s00415-004-0455-7
1432-1459
url https://www.arca.fiocruz.br/handle/icict/32991
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Springer Verlag
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