Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways

Detalhes bibliográficos
Autor(a) principal: Silva, Naylene C. S.
Data de Publicação: 2016
Outros Autores: Vale, Vladimir F., Franco, Paula F., Gontijo, Nelder F., Valenzuela, Jesus G., Pereira, Marcos H., Sant'Anna, Mauricio R. V., Rodrigues, Daniel S., Lima, Walter S., Fux, Blima, Araujo, Ricardo N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1186/s13071-016-1726-8
Texto Completo: https://www.arca.fiocruz.br/handle/icict/16590
Resumo: Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.
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spelling Silva, Naylene C. S.Vale, Vladimir F.Franco, Paula F.Gontijo, Nelder F.Valenzuela, Jesus G.Pereira, Marcos H.Sant'Anna, Mauricio R. V.Rodrigues, Daniel S.Lima, Walter S.Fux, BlimaAraujo, Ricardo N.2016-12-28T13:24:29Z2016-12-28T13:24:29Z2016SILVA, Naylene C. S. et al. Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical annd alternative complement pathways. Parasite & Vectors, v.9, n.445, 14p, 2016.1756-3305https://www.arca.fiocruz.br/handle/icict/1659010.1186/s13071-016-1726-8engBioMed CentralCaminho clássicoCaminho alternativoSalivaInibição do complementoRhipicephalus (Boophilus) microplusRhipicephalus (Boophilus) microplusSalivaComplement inhibitionClassical pathwayAlternative pathwaySaliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathwaysinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Simulídeos e Oncocercose. Rio de Janeiro, RJ, Brasil.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil.National Institute of Allergy and Infectious Diseases, NIH. Vector Molecular Biology Section. LMVR. Rockville, MD, USA.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.Empresa de Pesquisa Agropecuária de Minas Gerais. Fazenda Experimental Santa Rita. Prudente de Morais, MG.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.Universidade Federal do Espírito Santo. Departamento de Patologia. Vitória, ES, Brasil.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil.Rhipicephalus (Boophilus) microplus is the main ectoparasite affecting livestock worldwide. For a successful parasitism, ticks need to evade several immune responses of their hosts, including the activation of the complement system. In spite of the importance of R. microplus, previous work only identified one salivary molecule that blocks the complement system. The current study describes complement inhibitory activities induced by R. microplus salivary components and mechanisms elicited by putative salivary proteins on both classical and alternative complement pathways.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16590/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALvladimir2_vale_etal_IOC_2016.pdfvladimir2_vale_etal_IOC_2016.pdfapplication/pdf1407380https://www.arca.fiocruz.br/bitstream/icict/16590/2/vladimir2_vale_etal_IOC_2016.pdf44c0e6c82133635ffa1999c181a24071MD52TEXTvladimir2_vale_etal_IOC_2016.pdf.txtvladimir2_vale_etal_IOC_2016.pdf.txtExtracted texttext/plain66436https://www.arca.fiocruz.br/bitstream/icict/16590/3/vladimir2_vale_etal_IOC_2016.pdf.txt3cd9be127659db2375a0806f50f7a68bMD53icict/165902018-08-15 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dc.title.pt_BR.fl_str_mv Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
title Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
spellingShingle Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
Silva, Naylene C. S.
Caminho clássico
Caminho alternativo
Saliva
Inibição do complemento
Rhipicephalus (Boophilus) microplus
Rhipicephalus (Boophilus) microplus
Saliva
Complement inhibition
Classical pathway
Alternative pathway
title_short Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
title_full Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
title_fullStr Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
title_full_unstemmed Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
title_sort Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways
author Silva, Naylene C. S.
author_facet Silva, Naylene C. S.
Vale, Vladimir F.
Franco, Paula F.
Gontijo, Nelder F.
Valenzuela, Jesus G.
Pereira, Marcos H.
Sant'Anna, Mauricio R. V.
Rodrigues, Daniel S.
Lima, Walter S.
Fux, Blima
Araujo, Ricardo N.
author_role author
author2 Vale, Vladimir F.
Franco, Paula F.
Gontijo, Nelder F.
Valenzuela, Jesus G.
Pereira, Marcos H.
Sant'Anna, Mauricio R. V.
Rodrigues, Daniel S.
Lima, Walter S.
Fux, Blima
Araujo, Ricardo N.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Naylene C. S.
Vale, Vladimir F.
Franco, Paula F.
Gontijo, Nelder F.
Valenzuela, Jesus G.
Pereira, Marcos H.
Sant'Anna, Mauricio R. V.
Rodrigues, Daniel S.
Lima, Walter S.
Fux, Blima
Araujo, Ricardo N.
dc.subject.other.pt_BR.fl_str_mv Caminho clássico
Caminho alternativo
Saliva
Inibição do complemento
Rhipicephalus (Boophilus) microplus
topic Caminho clássico
Caminho alternativo
Saliva
Inibição do complemento
Rhipicephalus (Boophilus) microplus
Rhipicephalus (Boophilus) microplus
Saliva
Complement inhibition
Classical pathway
Alternative pathway
dc.subject.en.pt_BR.fl_str_mv Rhipicephalus (Boophilus) microplus
Saliva
Complement inhibition
Classical pathway
Alternative pathway
description Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Fisiologia de Insetos Hematófagos. Belo Horizonte, MG, Brasil.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-12-28T13:24:29Z
dc.date.available.fl_str_mv 2016-12-28T13:24:29Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Naylene C. S. et al. Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical annd alternative complement pathways. Parasite & Vectors, v.9, n.445, 14p, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/16590
dc.identifier.issn.pt_BR.fl_str_mv 1756-3305
dc.identifier.doi.none.fl_str_mv 10.1186/s13071-016-1726-8
identifier_str_mv SILVA, Naylene C. S. et al. Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical annd alternative complement pathways. Parasite & Vectors, v.9, n.445, 14p, 2016.
1756-3305
10.1186/s13071-016-1726-8
url https://www.arca.fiocruz.br/handle/icict/16590
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/16590/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/16590/2/vladimir2_vale_etal_IOC_2016.pdf
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