Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region

Detalhes bibliográficos
Autor(a) principal: Spitz, Natália
Data de Publicação: 2015
Outros Autores: Mello, Francisco C. A., Araujo, Natalia Motta
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/11507
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.
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spelling Spitz, NatáliaMello, Francisco C. A.Araujo, Natalia Motta2015-08-19T13:49:24Z2015-08-19T13:49:24Z2015SPITZ, Natália; MELLO, Francisco C. A.; ARAUJO, Natalia Motta. Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region. Mem Inst Oswaldo Cruz, v.110, n.1, p.151-153, Feb, 2015.1678-8060https://www.arca.fiocruz.br/handle/icict/1150710.1590/0074-02760140426engFundação Oswaldo CruzRegião AmazônicaHBVComplete genomeAmino acid residuesGenetic distancesubgenotype D3Vírus da Hepatite BGenótipoFull-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Regioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/11507/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALnatalia_spitz_etal_IOC_2015.pdfapplication/pdf957110https://www.arca.fiocruz.br/bitstream/icict/11507/2/natalia_spitz_etal_IOC_2015.pdf49b0311b1ec6502d936b592ed417f3f0MD52TEXTnatalia_spitz_etal_IOC_2015.pdf.txtnatalia_spitz_etal_IOC_2015.pdf.txtExtracted texttext/plain12409https://www.arca.fiocruz.br/bitstream/icict/11507/3/natalia_spitz_etal_IOC_2015.pdf.txt4dea13ade1265d3a8653ccdf777ee999MD53icict/115072022-06-24 13:11:03.828oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:11:03Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
title Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
spellingShingle Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
Spitz, Natália
Região Amazônica
HBV
Complete genome
Amino acid residues
Genetic distance
subgenotype D3
Vírus da Hepatite B
Genótipo
title_short Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
title_full Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
title_fullStr Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
title_full_unstemmed Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
title_sort Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
author Spitz, Natália
author_facet Spitz, Natália
Mello, Francisco C. A.
Araujo, Natalia Motta
author_role author
author2 Mello, Francisco C. A.
Araujo, Natalia Motta
author2_role author
author
dc.contributor.author.fl_str_mv Spitz, Natália
Mello, Francisco C. A.
Araujo, Natalia Motta
dc.subject.other.pt_BR.fl_str_mv Região Amazônica
topic Região Amazônica
HBV
Complete genome
Amino acid residues
Genetic distance
subgenotype D3
Vírus da Hepatite B
Genótipo
dc.subject.en.pt_BR.fl_str_mv HBV
Complete genome
Amino acid residues
Genetic distance
subgenotype D3
dc.subject.decs.pt_BR.fl_str_mv Vírus da Hepatite B
Genótipo
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.accessioned.fl_str_mv 2015-08-19T13:49:24Z
dc.date.available.fl_str_mv 2015-08-19T13:49:24Z
dc.date.issued.fl_str_mv 2015
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SPITZ, Natália; MELLO, Francisco C. A.; ARAUJO, Natalia Motta. Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region. Mem Inst Oswaldo Cruz, v.110, n.1, p.151-153, Feb, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/11507
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/0074-02760140426
identifier_str_mv SPITZ, Natália; MELLO, Francisco C. A.; ARAUJO, Natalia Motta. Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region. Mem Inst Oswaldo Cruz, v.110, n.1, p.151-153, Feb, 2015.
1678-8060
10.1590/0074-02760140426
url https://www.arca.fiocruz.br/handle/icict/11507
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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