Myeloid Metaplasia of Spleen in Hookworm Disease

Detalhes bibliográficos
Autor(a) principal: Cruz, W. O.
Data de Publicação: 1934
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48116
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
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spelling Cruz, W. O.2021-07-11T18:03:02Z2021-07-11T18:03:02Z1934CRUZ, W. O. Myeloid Metaplasia of Spleen in Hookworm Disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 28, n. 2, p. 1-5. jun. 1934.0074-0276https://www.arca.fiocruz.br/handle/icict/4811610.1590/S0074-027619340002000131678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Metaplasia mieloideBaçoDoença da minhocaMyeloid MetaplasiaSpleenHookworm DiseaseMyeloid Metaplasia of Spleen in Hookworm Diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.We investigated, in the liver and the spleen of ten pures cases of ankylostomiasis haemocytopoietic elements. We verified the weight of spleen in 23 cases of individuals from 3 to 60 years old. In no case did we meet with haemopoietic cells in liver. In seven cases we found in spleen elements of the red series at an advanced evolutional stage (orthochromatic erythroblasts with pyknotic nucleus). In some of these cases we observed megakaryocytes and numerous eosinophilous myelocytes.The three cases which did not show any myeloid metaplasia in spleen were from individuals of over 50 years. Nevertheless, in another case of an individual 59 years old this metaplasia was verified. In individuals of over 20 years, the average weight of spleen in nine cases appeared to be equal to the normal weight. In 14 other cases, between 3 and 14 years of age, the weight of this organ was always sensibly higher than in normal individuals of the corresponding age. These results suggest the possibility of the myeloid metaplasia being the fact responsible for the weight increase of spleen in young individuals victimatized by hookworm anaemia. The remarkable proliferation of orthochromatic erythroblasts shows that the degree and quickness of blood regeneration after iron administration are due, essentially, to the great quantity of haemoglobin previously formed in the spleen and bone marrow of ankylostomized organisms.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48116/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALWO_Cruz_IOC_ing_v28n2_jun1934.pdfWO_Cruz_IOC_ing_v28n2_jun1934.pdfapplication/pdf1741201https://www.arca.fiocruz.br/bitstream/icict/48116/2/WO_Cruz_IOC_ing_v28n2_jun1934.pdf36f256bb24314c79393eca9494e61d34MD52TEXTWO_Cruz_IOC_ing_v28n2_jun1934.pdf.txtWO_Cruz_IOC_ing_v28n2_jun1934.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Myeloid Metaplasia of Spleen in Hookworm Disease
title Myeloid Metaplasia of Spleen in Hookworm Disease
spellingShingle Myeloid Metaplasia of Spleen in Hookworm Disease
Cruz, W. O.
Metaplasia mieloide
Baço
Doença da minhoca
Myeloid Metaplasia
Spleen
Hookworm Disease
title_short Myeloid Metaplasia of Spleen in Hookworm Disease
title_full Myeloid Metaplasia of Spleen in Hookworm Disease
title_fullStr Myeloid Metaplasia of Spleen in Hookworm Disease
title_full_unstemmed Myeloid Metaplasia of Spleen in Hookworm Disease
title_sort Myeloid Metaplasia of Spleen in Hookworm Disease
author Cruz, W. O.
author_facet Cruz, W. O.
author_role author
dc.contributor.author.fl_str_mv Cruz, W. O.
dc.subject.other.pt_BR.fl_str_mv Metaplasia mieloide
Baço
Doença da minhoca
topic Metaplasia mieloide
Baço
Doença da minhoca
Myeloid Metaplasia
Spleen
Hookworm Disease
dc.subject.en.pt_BR.fl_str_mv Myeloid Metaplasia
Spleen
Hookworm Disease
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
publishDate 1934
dc.date.issued.fl_str_mv 1934
dc.date.accessioned.fl_str_mv 2021-07-11T18:03:02Z
dc.date.available.fl_str_mv 2021-07-11T18:03:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CRUZ, W. O. Myeloid Metaplasia of Spleen in Hookworm Disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 28, n. 2, p. 1-5. jun. 1934.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48116
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S0074-02761934000200013
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv CRUZ, W. O. Myeloid Metaplasia of Spleen in Hookworm Disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 28, n. 2, p. 1-5. jun. 1934.
0074-0276
10.1590/S0074-02761934000200013
1678-8060
url https://www.arca.fiocruz.br/handle/icict/48116
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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