Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/13770 |
Resumo: | Federal University of Rondônia. Department of Biology. Laboratory of Insect Bioecology. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Porto Velho, RO, Brazil. |
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Trindade, Frances T.T.Soares, Ângela A.Moura, Andréa A. deRego, Tiago B.Soares, Andreimar M.Stábeli, Rodrigo G.Calderon, Leonardo A.Silva, Alexandre de Almeida e2016-04-14T15:10:54Z2016-04-14T15:10:54Z2014Silva, A. A., et al. Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti. The Journal of Venomous Animals and Toxins Including Tropical Diseases (Online), v. 20, p. 28, 2014.https://www.arca.fiocruz.br/handle/icict/13770doi:10.1186/1678-9199-20-28engJournal of Venomous Animals and Toxins including Tropical DiseasesInsecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegyptiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Rondônia. Department of Biology. Laboratory of Insect Bioecology. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Center for the Study of Biomolecules Applicable to Health. Department of Medicine. Federal University of Rondônia. Porto Velho, RO, Brazil.Federal University of Rondônia. Department of Biology. Laboratory of Insect Bioecology. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Porto Velho, RO, Brazil.Background: Mosquitoes are important vectors of several diseases, including malaria and dengue, and control measures are mostly performed using chemical insecticides. Unfortunately, mosquito resistance to commonly applied insecticides is widespread. There fore, a prospection for new molecules with insecticidal activity based on Amazon biodiversity using the anurans Leptodactylus knudseni and Phyllomedusa vaillantii was performed against the mosquito species Anopheles darlingi and Aedes aegypti. Methods: The granular secretion from anuran skin was obtained by manual stimulation, and lethal concentrations (LCs) for larvicidal and adulticidal tests were calculated using concentrations from 1-100 ppm. The skin secretions from the anuran species tested caused significant mortality within the first 24 hours on adults and larvae, but differed within the mosquito species. Results: The skin secretions from the anuran species tested caused significant mortality within the first 24 hours on adults and larvae, but differed within the mosquito species. The calculated LC50 of L. knudseni skin secretions against An. darlingi was 0.15 and 0.2 ppm for adults and larvae, respectively, but much higher for Ae. aegypti, i.e., 19 and 38 ppm, respectively. Interestingly, the calculated LCs50 of P. vaillantii against both mosquito species in adults were similar, 1.8 and 2.1 ppm, respectively, but the LC50 for An. darlingi larvae was much lower (0.4 ppm) than for Ae aegypti (2.1 ppm). Conclusions: The present experiments indicate that skin secretions from L. knudseni and P. vaillantii contain bioactive molecules with potent insecticide activity. The isolation and characterization of skin secretions components will provide new insights for potential insecticidal molecules.Vector controlAnuran amphibiansDengueMalariainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13770/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALInsecticidal activity of Leptodactylus knudseni.pdfInsecticidal activity of Leptodactylus knudseni.pdfapplication/pdf649448https://www.arca.fiocruz.br/bitstream/icict/13770/2/Insecticidal%20activity%20of%20Leptodactylus%20knudseni.pdf8b320993fbfe6137b630148a7c6c33eeMD52TEXTInsecticidal activity of Leptodactylus knudseni.pdf.txtInsecticidal activity of Leptodactylus knudseni.pdf.txtExtracted 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Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| title |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| spellingShingle |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti Trindade, Frances T.T. Vector control Anuran amphibians Dengue Malaria |
| title_short |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| title_full |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| title_fullStr |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| title_full_unstemmed |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| title_sort |
Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti |
| author |
Trindade, Frances T.T. |
| author_facet |
Trindade, Frances T.T. Soares, Ângela A. Moura, Andréa A. de Rego, Tiago B. Soares, Andreimar M. Stábeli, Rodrigo G. Calderon, Leonardo A. Silva, Alexandre de Almeida e |
| author_role |
author |
| author2 |
Soares, Ângela A. Moura, Andréa A. de Rego, Tiago B. Soares, Andreimar M. Stábeli, Rodrigo G. Calderon, Leonardo A. Silva, Alexandre de Almeida e |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Trindade, Frances T.T. Soares, Ângela A. Moura, Andréa A. de Rego, Tiago B. Soares, Andreimar M. Stábeli, Rodrigo G. Calderon, Leonardo A. Silva, Alexandre de Almeida e |
| dc.subject.en.pt_BR.fl_str_mv |
Vector control Anuran amphibians Dengue Malaria |
| topic |
Vector control Anuran amphibians Dengue Malaria |
| description |
Federal University of Rondônia. Department of Biology. Laboratory of Insect Bioecology. Porto Velho, RO, Brazil. / Oswaldo Cruz Foundation. Porto Velho, RO, Brazil. |
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2014 |
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2014 |
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2016-04-14T15:10:54Z |
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2016-04-14T15:10:54Z |
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info:eu-repo/semantics/article |
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Silva, A. A., et al. Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti. The Journal of Venomous Animals and Toxins Including Tropical Diseases (Online), v. 20, p. 28, 2014. |
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https://www.arca.fiocruz.br/handle/icict/13770 |
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doi:10.1186/1678-9199-20-28 |
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Silva, A. A., et al. Insecticidal activity of Leptodactylus knudseni and Phyllomedusa vaillantii crude skin secretions against the mosquitoes Anopheles darlingi and Aedes aegypti. The Journal of Venomous Animals and Toxins Including Tropical Diseases (Online), v. 20, p. 28, 2014. doi:10.1186/1678-9199-20-28 |
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Journal of Venomous Animals and Toxins including Tropical Diseases |
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Journal of Venomous Animals and Toxins including Tropical Diseases |
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