Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/34311 |
Resumo: | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. |
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Sampaio, Felipe Maurício SoeiroWanke, BodoFreitas, Dayvison Francis SaraivaCoelho, Janice Mery Chicarino de OliveiraGalhardo, Maria Clara GutierrezLyra, Marcelo RosandiskiLourenço, Maria Cristina da SilvaPaes, Rodrigo de AlmeidaValle, Antonio Carlos Francesconi do2019-07-22T13:19:09Z2019-07-22T13:19:09Z2017SAMPAIO, Felipe Maurício Soeiro. Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil. Plos Neglected Tropical Diseases, p. 1-18, Feb. 2017.1935-2727https://www.arca.fiocruz.br/handle/icict/3431110.1371/journal.pntd.00053011935-2735engPublic Library of ScienceReview of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Mycetoma is caused by the subcutaneous inoculation of filamentous fungi or aerobic filamentous bacteria that form grains in the tissue. The purpose of this study is to describe the epidemiologic, clinic, laboratory, and therapeutic characteristics of patients with mycetoma at the Oswaldo Cruz Foundation in Rio de Janeiro, Brazil, between 1991 and 2014. Twenty-one cases of mycetoma were included in the study. There was a predominance of male patients (1.3:1) and the average patient age was 46 years. The majority of the cases were from the Southeast region of Brazil and the feet were the most affected anatomical region (80.95%). Eumycetoma prevailed over actinomycetoma (61.9% and 38.1% respectively). Eumycetoma patients had positive cultures in 8 of 13 cases, with isolation of Scedosporium apiospermum species complex (n = 3), Madurella mycetomatis (n = 2) and Acremonium spp. (n = 1). Two cases presented sterile mycelium and five were negative. Six of 8 actinomycetoma cases had cultures that were identified as Nocardia spp. (n = 3), Nocardia brasiliensis (n = 2), and Nocardia asteroides (n = 1). Imaging tests were performed on all but one patients, and bone destruction was identified in 9 cases (42.68%). All eumycetoma cases were treated with itraconazole monotherapy or combined with fluconazole, terbinafine, or amphotericin B. Actinomycetoma cases were treated with sulfamethoxazole plus trimethoprim or combined with cycles of amikacin sulphate. Surgical procedures were performed in 9 (69.2%) eumycetoma and in 3 (37.5%) actinomycetoma cases, with one amputation case in each group. Clinical cure occurred in 11 cases (7 for eumycetoma and 4 for actinomycetoma), and recurrence was documented in 4 of 21 cases. No deaths were recorded during the study. Despite of the scarcity of mycetoma in our institution the cases presented reflect the wide clinical spectrum and difficulties to take care of this neglected disease.MycetomaRio de JaneiroBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/34311/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Sampaio_Felipe_etal_INI_2017.pdfve_Sampaio_Felipe_etal_INI_2017.pdfapplication/pdf1737175https://www.arca.fiocruz.br/bitstream/icict/34311/2/ve_Sampaio_Felipe_etal_INI_2017.pdfb56b57983669486175819846a0001025MD52TEXTve_Sampaio_Felipe_etal_INI_2017.pdf.txtve_Sampaio_Felipe_etal_INI_2017.pdf.txtExtracted texttext/plain51107https://www.arca.fiocruz.br/bitstream/icict/34311/3/ve_Sampaio_Felipe_etal_INI_2017.pdf.txtd69163b35db14c3b30de0c548fc29d5bMD53icict/343112019-07-23 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| dc.title.pt_BR.fl_str_mv |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| title |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| spellingShingle |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil Sampaio, Felipe Maurício Soeiro Mycetoma Rio de Janeiro Brazil |
| title_short |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| title_full |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| title_fullStr |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| title_full_unstemmed |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| title_sort |
Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil |
| author |
Sampaio, Felipe Maurício Soeiro |
| author_facet |
Sampaio, Felipe Maurício Soeiro Wanke, Bodo Freitas, Dayvison Francis Saraiva Coelho, Janice Mery Chicarino de Oliveira Galhardo, Maria Clara Gutierrez Lyra, Marcelo Rosandiski Lourenço, Maria Cristina da Silva Paes, Rodrigo de Almeida Valle, Antonio Carlos Francesconi do |
| author_role |
author |
| author2 |
Wanke, Bodo Freitas, Dayvison Francis Saraiva Coelho, Janice Mery Chicarino de Oliveira Galhardo, Maria Clara Gutierrez Lyra, Marcelo Rosandiski Lourenço, Maria Cristina da Silva Paes, Rodrigo de Almeida Valle, Antonio Carlos Francesconi do |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Sampaio, Felipe Maurício Soeiro Wanke, Bodo Freitas, Dayvison Francis Saraiva Coelho, Janice Mery Chicarino de Oliveira Galhardo, Maria Clara Gutierrez Lyra, Marcelo Rosandiski Lourenço, Maria Cristina da Silva Paes, Rodrigo de Almeida Valle, Antonio Carlos Francesconi do |
| dc.subject.en.pt_BR.fl_str_mv |
Mycetoma Rio de Janeiro Brazil |
| topic |
Mycetoma Rio de Janeiro Brazil |
| description |
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. |
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2017 |
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2017 |
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2019-07-22T13:19:09Z |
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2019-07-22T13:19:09Z |
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info:eu-repo/semantics/publishedVersion |
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SAMPAIO, Felipe Maurício Soeiro. Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil. Plos Neglected Tropical Diseases, p. 1-18, Feb. 2017. |
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https://www.arca.fiocruz.br/handle/icict/34311 |
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1935-2727 |
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10.1371/journal.pntd.0005301 |
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1935-2735 |
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SAMPAIO, Felipe Maurício Soeiro. Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil. Plos Neglected Tropical Diseases, p. 1-18, Feb. 2017. 1935-2727 10.1371/journal.pntd.0005301 1935-2735 |
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